EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
Nucleotide sugar epimerase/dehydratase WbpMwbpM PA3141Q9HZ863
Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein (OppA)HP_1252O258453
Oligopeptide-binding protein OppA (Stage 0 sporulation protein KA)oppA spo0KA BSU11430P241413
OmpA domain proteinMXAN_5598Q1D0T63
OmpA family proteinfopA FTN_0756A0Q5Y23
OmpA family proteinFTN_0346A0Q4T73
OmpA family proteinPP_1121Q88NT33
OmpA family proteinPP_1502Q88MR73
OmpA family proteinPP_4198Q88FA03
OmpA family proteinPP_4669Q88DZ93
OmpA family proteinPP_1122Q88NT23
OmpA/MotB domain-containing proteinyiaD PP_0773Q88PS53
Orotidine 5'-phosphate decarboxylase (EC (OMP decarboxylase) (OMPDCase) (OMPdecase)pyrF BE932_02265 SY51_07890A0A061YJC83
Osmotically-inducible putative lipoprotein OsmE (Activator of ntr-like gene protein)osmE anr b1739 JW1728P0ADB13
Outer membrane copper receptor OprCoprC PP_4838Q88DI73
Outer membrane efflux proteinPP_4923Q88DA43
Outer membrane efflux protein, tolCtolC FTN_1703A0Q8J53
Outer membrane ferripyoverdine receptor FpvA, TonB-dependentfpvA PP_4217Q88F813
Outer membrane fibronectin-binding proteincadF Cj1478cQ0P8D93
Outer membrane lipoproteinslyB PP_1131Q88NS33
Outer membrane lipoprotein SlyBslyB b1641 JW1633P0A9053
Outer membrane porin FoprF PP_2089Q88L463
Outer membrane protein (Omp2)HP_0025O248703
Outer membrane protein (Omp3)HP_0079O249083
Outer membrane protein 3b (A), protease VII (Protease)ompT EC958_0673 UG58_01860W8ZNZ03
Outer membrane protein assembly factor BamAbamA Cj0129cQ0PC083
Outer membrane protein assembly factor BamAbamA bamA-I PP_1599Q88MH23
Outer membrane protein assembly factor BamAbamA Smlt1498B2FIA03
Outer membrane protein assembly factor BamA (Omp85)bamA yaeT yzzN yzzY b0177 JW0172P0A9403
Outer membrane protein assembly factor BamBbamB PP_0856Q88PJ43
Outer membrane protein assembly factor BamDbamD yfiO b2595 JW2577P0AC023
Outer membrane protein assembly factor BamDbamD PP_0622Q88Q733
Outer membrane protein assembly factor BamDbamD yfiO Z3889 ECs3458P0AC043
Outer membrane protein assembly factor BamEbamE PP_4731Q88DT83
Outer membrane protein assembly factor BamEbamE smpA b2617 JW2598P0A9373
Outer membrane protein C (Outer membrane protein 1B) (Porin OmpC)ompC Z3473 ECs3104Q8XE413
Outer membrane protein F (Outer membrane protein 1A) (Outer membrane protein B) (Outer membrane protein IA) (Porin OmpF)ompF cmlB coa cry tolF b0929 JW0912P029313
Outer membrane protein H.8NMB1533P570263
Outer membrane protein H1oprH PP_1185Q88NM23
Outer membrane protein induced after carbon starvation (Slp family outer membrane lipoprotein)slp slp_1 AC789_1c38740 ERS150876_00023A0A0E1LDD53
Outer membrane protein Omp38omp38 A1S_2840A3M8K23
Outer membrane protein OmpHompH FTN_1481A0Q7Y33
Outer membrane protein OprGoprG PP_0504Q88QI83
Outer membrane protein slpslp b3506 JW3474P371943
Outer membrane protein Slp (Outer membrane protein induced after carbon starvation)slp ECs4377 Z4908Q8X5P53
Outer membrane protein WompW yciD b1256 JW1248P0A9153
Outer membrane protein W (Putative outer membrane protein)yciD ompW ECs1756 Z2034Q8XCB63
Outer membrane protein XompX Z1036 ECs0892P0A9193
Outer-membrane lipoprotein LolBlolB PP_0724Q88PX43
Outer-membrane lipoprotein LolBlolB Smlt0873B2FQ173
Outer-membrane porin D (EC 3.4.21.-)oprQ PP_0268Q88R663
Outer-membrane porin E (EC 3.4.21.-)oprE PP_0234Q88R993
Oxidative stress defense proteinBE932_12665 ERS085366_00819 SY51_16390A0A061KYU03
OxidoreductaseBE932_03525 SY51_09070A0A066SVM53
Oxygen-independent coproporphyrinogen III oxidase (CPO) (EC (Coproporphyrinogen III dehydrogenase) (CPDH)hemN PA1546P779153
Paraquat-inducible protein BPP_0599Q88Q963
Penicillin acylase family proteinMXAN_2906Q1D8A63
Penicillin-binding protein 1A/1B (PBP1) [Includes: Penicillin-insensitive transglycosylase (EC (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (EC (DD-transpeptidase)]ponA BSU22320P397933
Penicillin-binding protein 1B (PBP-1b) (PBP1b) (Murein polymerase)mrcB PA4700G3XD313
Penicillin-binding protein 3 (PBP 3) (PSPB20) (Penicillin-binding protein C)pbpC ycsM yzsA BSU04140P429713
Penicillin-binding protein activator LpoA (PBP activator LpoA) (Lipoprotein activator of PBP from the outer membrane A)lpoA yraM b3147 JW3116P454643
Penicillin-binding protein activator LpoB (PBP activator LpoB)lpoB BET08_26000 BK337_21960 BUE81_21320A0A0A6UCV43
Peptidase U35PP_1566Q88MK53
Peptidase, M36 (Fungalysin) family (EC 3.4.-.-)MXAN_3564Q1D6G93
Peptidase, S1A (Chymotrypsin) subfamily (EC 3.4.21.-)MXAN_1650Q1DBS13
Peptidase, S9C (Acylaminoacyl-peptidase) subfamily (EC 3.4.-.-)MXAN_6601Q1CY033
Peptide ABC transporter substrate-binding proteinBY96_03865A0A027U4C03
Peptide deformylase (PDF) (EC (Polypeptide deformylase)def BET08_18245 BK337_16925 BUE81_25685A0A0A6R6143
Peptide methionine sulfoxide reductase MsrA/MsrB [Includes: Thioredoxin; Peptide methionine sulfoxide reductase MsrA (Protein-methionine-S-oxide reductase) (EC (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase); Peptide methionine sulfoxide reductase MsrB (EC (Peptide-methionine (R)-S-oxide reductase)]msrAB pilB NMB0044Q9K1N83
Peptidoglycan-associated lipoproteinpal oprL pal1 PP_1223P0A1383
Peptidoglycan-associated lipoproteinpal Z0909 ECs0776P0A9133
Peptidoglycan-associated lipoprotein, OmpA familypal FTN_0357A0Q4U83
Peptidoglycan-binding protein (Peptidoglycan-binding protein LysM) (Putative peptidoglycan-binding protein) (Putative uncharacterized protein)ygaU A5958_16710 AA102_05120 ACN77_20570 ACN81_20545 ACN87_06915 ACU90_16385 AKG99_02960 AM270_01505 AMK83_09495 AML07_11840 AML35_05900 APZ14_09895 ARC77_09540 AU473_08610 AUS26_10540 BE957_09465 BHS81_16050 BK251_07065 BK292_15255 BMT53_21820 BMT61_21555 BMT91_21415 BWP17_12870 ECs3526 ERS085374_03231 ERS085379_00719 ERS085383_02332 ERS085386_03319 ERS085404_02124 ERS150876_01340 FORC28_1241 GJ12_17380 HW42_17915 PU06_25570 RG28_08305 UN86_27175C3SYE73
Peptidyl-prolyl cis-trans isomerase (EC
Peptidyl-prolyl cis-trans isomerase (EC PP_1714Q88M603
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC UC41_08760A0A0D8WE883
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC (Cyclophilin A) (Rotamase A)ppiA Z4724 ECs4214P0AFL53
Peptidyl-tRNA hydrolase (PTH) (EC BE932_30690 SY51_07025A0A066T1033
Peptidylprolyl isomerase (EC
Peptidylprolyl isomerase (EC SY51_02310A0A066T5W93
Periplasmic cystine-binding proteinfliY PP_0227Q88RA63
Periplasmic nitrate reductase (EC Cj0780Q9PPD93
Periplasmic protein DcrBdcrB A4T50_11545 APU18_01205 BE932_16325 BK373_21180 BMT49_24170 BV389_25590 ERS085406_01776 MJ49_12930 SY51_19815 UN91_22025 WM48_19205E2QFX63
Periplasmic serine endoprotease DegP (EC (Heat shock protein DegP) (Protease Do)degP htrA ptd b0161 JW0157P0C0V03
Peroxiredoxin (Thiol peroxidase) (EC BV389_21970 UN91_14120A0A0F3UGQ53
Persistence and stress-resistance toxin PasT (Ribosome association toxin RatA)pasT ratA yfjG c3141Q8FEY43
Phage minor tail protein G (Tail protein)BE932_30155 SY51_06490A0A066SWW03
Phage portal protein (Plasmid partitioning protein ParB)BE932_30110 SY51_06445A0A061Y8553
Phage portal protein, HK97 familyPP_1565Q88MK63
Phage protein (Prophage protein)A5958_01720 AML07_04010 APT94_26570 APZ14_29570 AUS26_02580 BE957_11000 BWP17_26980 ERS085383_05319 ERS085386_05300 ERS085404_04777 FORC28_1805 FORC28_2485A0A066RBP13
Phage tail proteinBE932_30195 SY51_06530A0A066T1C83
Phage tail tape meausure protein, lambda familyPP_1577Q88MJ43
Phenylalanine--tRNA ligase beta subunit (EC (Phenylalanyl-tRNA synthetase beta subunit) (PheRS)pheT PA2739Q9I0A43
Phosphatase NagDECSE_0735B6HYN33
Phosphate acetyltransferase (EC (Phosphotransacetylase)pta E2348C_2437B7UFV53
Phosphate acetyltransferase (EC (Phosphotransacetylase)pta A4T50_04540 APU18_03110 BE932_09095 ERS085406_01042 SY51_13135E2QPF83
Phosphate import ATP-binding protein PstB 2 (EC (ABC phosphate transporter 2) (Phosphate-transporting ATPase 2)pstB2 spr1254Q8DPB43
Phosphate-binding protein PstSpstS A4T40_24515 AC067_07110 BK334_16130 ECONIH1_21940 MS6198_42910A0A0A1AC883
Phosphate-specific transport system accessory protein PhoUphoU A4T40_24535 AML35_24020 APT94_10120 ARC77_15530 AU473_02330 BE949_21380 BE963_09855 BHF46_03315 BIQ85_21170 BK248_08325 BK334_16150 BK375_10315 BK383_23325 BK400_01075 BMT94_11670 BMT97_04470 BUE82_25030 BV389_10035 BWP17_17305 BXT93_11130 ECONIH1_21920 ECs4660 ERS085366_03563 ERS085383_02594 ERS085404_03547 GJ11_23800 HMPREF3040_01853 JD73_04815 MS6198_42870 SM09_04711 UC41_07960 UN91_09845C3SLE73
Phospho-2-dehydro-3-deoxyheptonate aldolase (EC (3-deoxy-D-arabino-heptulosonate 7-phosphate synthase) (DAHP synthase) (Phospho-2-keto-3-deoxyheptonate aldolase)BE932_27430 BK248_02350 BK400_14395 SY51_03850A0A061KPI63
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