EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding protein 1)NFX1 NFX2Q1298612
Translocon-associated protein subunit beta (TRAP-beta) (Signal sequence receptor subunit beta) (SSR-beta)SSR2 TRAPB HSD25P4330812
Transmembrane protein 258TMEM258 C11orf10 HSPC005P6116512
Transportin-2 (Karyopherin beta-2b)TNPO2O1478712
Trifunctional enzyme subunit alpha, mitochondrial (78 kDa gastrin-binding protein) (TP-alpha) [Includes: Long-chain enoyl-CoA hydratase (EC; Long chain 3-hydroxyacyl-CoA dehydrogenase (EC]HADHA HADHP4093912
Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)]GART PGFT PRGSP2210212
TSC22 domain family protein 1 (Cerebral protein 2) (Regulatory protein TSC-22) (TGFB-stimulated clone 22 homolog) (Transforming growth factor beta-1-induced transcript 4 protein)TSC22D1 KIAA1994 TGFB1I4 TSC22 hucep-2Q1571412
Tubulin beta-6 chain (Tubulin beta class V)TUBB6Q9BUF512
Tubulin-specific chaperone D (Beta-tubulin cofactor D) (tfcD) (SSD-1) (Tubulin-folding cofactor D)TBCD KIAA0988 SSD1 TFCD PP1096Q9BTW912
U6 snRNA-associated Sm-like protein LSm4 (Glycine-rich protein) (GRP)LSM4Q9Y4Z012
Ubiquitin-conjugating enzyme E2 G2 (EC (Ubiquitin carrier protein G2) (Ubiquitin-protein ligase G2)UBE2G2P6060412
Ubiquitin-like protein 5UBL5Q9BZL112
UBX domain-containing protein 1 (SAPK substrate protein 1) (UBA/UBX 33.3 kDa protein)UBXN1 SAKS1Q0432312
UDP-glucose 4-epimerase (EC (Galactowaldenase) (UDP-galactose 4-epimerase)GALEQ1437612
Uncharacterized protein C8orf59C8orf59Q8N0T112
UPF0449 protein C19orf25C19orf25Q9UFG512
UV excision repair protein RAD23 homolog A (HR23A) (hHR23A)RAD23AP5472512
V-type proton ATPase subunit B, brain isoform (V-ATPase subunit B 2) (Endomembrane proton pump 58 kDa subunit) (HO57) (Vacuolar proton pump subunit B 2)ATP6V1B2 ATP6B2 VPP3P2128112
Vigilin (High density lipoprotein-binding protein) (HDL-binding protein)HDLBP HBP VGLQ0034112
WW domain-binding protein 1 (WBP-1)WBP1Q96G2712
Zinc finger protein 148 (Transcription factor ZBP-89) (Zinc finger DNA-binding protein 89)ZNF148 ZBP89Q9UQR112
Zinc finger protein 160 (Zinc finger protein HZF5) (Zinc finger protein Kr18) (HKr18)ZNF160 KIAA1611Q9HCG112
Zinc finger Ran-binding domain-containing protein 2 (Zinc finger protein 265) (Zinc finger, splicing)ZRANB2 ZIS ZNF265O9521812
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1 (EC 1.14.11.-) (Termination and polyadenylation 1 homolog)OGFOD1 KIAA1612 TPA1Q8N54311
28S ribosomal protein S29, mitochondrial (MRP-S29) (S29mt) (Death-associated protein 3) (DAP-3) (Ionizing radiation resistance conferring protein)DAP3 MRPS29P5139811
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC (3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H)HIBCHQ6NVY111
39S ribosomal protein L12, mitochondrial (L12mt) (MRP-L12) (5c5-2)MRPL12 RPML12P5281511
39S ribosomal protein L18, mitochondrial (L18mt) (MRP-L18)MRPL18 HSPC071Q9H0U611
39S ribosomal protein L20, mitochondrial (L20mt) (MRP-L20)MRPL20Q9BYC911
39S ribosomal protein L43, mitochondrial (L43mt) (MRP-L43) (Mitochondrial ribosomal protein bMRP36a)MRPL43Q8N98311
40S ribosomal protein S19RPS19P3901911
40S ribosomal protein S21RPS21P6322011
60S ribosomal protein L18aRPL18AQ0254311
60S ribosomal protein L23 (60S ribosomal protein L17)RPL23P6282911
60S ribosomal protein L35RPL35P4276611
60S ribosomal protein L36a-likeRPL36ALQ969Q011
60S ribosomal protein L37 (G1.16)RPL37P6192711
Acetyl-coenzyme A synthetase, cytoplasmic (EC (Acetate--CoA ligase) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) (Acyl-activating enzyme)ACSS2 ACAS2Q9NR1911
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL-6-interacting protein 1) (Aip-1)ARL6IP1 ARL6IP KIAA0069Q1504111
Aldo-keto reductase family 1 member C2 (EC 1.-.-.-) (3-alpha-HSD3) (Chlordecone reductase homolog HAKRD) (Dihydrodiol dehydrogenase 2) (DD-2) (DD2) (Dihydrodiol dehydrogenase/bile acid-binding protein) (DD/BABP) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC (Type III 3-alpha-hydroxysteroid dehydrogenase) (EC DDH2P5289511
Alpha-actinin-4 (F-actin cross-linking protein) (Non-muscle alpha-actinin 4)ACTN4O4370711
Alpha-adducin (Erythrocyte adducin subunit alpha)ADD1 ADDAP3561111
Amyloid-like protein 2 (APLP-2) (APPH) (Amyloid protein homolog) (CDEI box-binding protein) (CDEBP)APLP2 APPL2Q0648111
Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc finger MYND domain-containing protein 13)ANKMY1 TSAL1 ZMYND13Q9P2S611
Annexin A11 (56 kDa autoantigen) (Annexin XI) (Annexin-11) (Calcyclin-associated annexin 50) (CAP-50)ANXA11 ANX11P5099511
Apoptosis regulator BAX (Bcl-2-like protein 4) (Bcl2-L-4)BAX BCL2L4Q0781211
Armadillo repeat-containing protein 10 (Splicing variant involved in hepatocarcinogenesis protein)ARMC10 SVH PSEC0198Q8N2F611
Aspartate beta-hydroxylase domain-containing protein 1 (EC 1.14.11.-)ASPHD1Q5U4P211
Aspartate--tRNA ligase, cytoplasmic (EC (Aspartyl-tRNA synthetase) (AspRS) (Cell proliferation-inducing gene 40 protein)DARS PIG40P1486811
ATP synthase subunit s, mitochondrial (ATP synthase-coupling factor B) (FB) (Mitochondrial ATP synthase regulatory component factor B)ATP5S ATPWQ9976611
ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein)ABCF1 ABC50Q8NE7111
ATP-dependent DNA helicase Q1 (EC (DNA helicase, RecQ-like type 1) (RecQ1) (DNA-dependent ATPase Q1) (RecQ protein-like 1)RECQL RECQ1 RECQL1P4606311
Aurora kinase A-interacting protein (AURKA-interacting protein) (28S ribosomal protein S38, mitochondrial) (MRP-S38)AURKAIP1 AIP AKIP MRPS38Q9NWT811
B-cell CLL/lymphoma 7 protein family member CBCL7CQ8WUZ011
BAG family molecular chaperone regulator 5 (BAG-5) (Bcl-2-associated athanogene 5)BAG5 KIAA0873Q9UL1511
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)BCL2L1 BCL2L BCLXQ0781711
Biliverdin reductase A (BVR A) (EC (Biliverdin-IX alpha-reductase)BLVRA BLVR BVRP5300411
BolA-like protein 3BOLA3Q53S3311
C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (Cancer/testis antigen 89) (CT89) (Human lung cancer oncogene 6 protein) (HLC-6) (JNK-associated leucine-zipper protein) (JLP) (Mitogen-activated protein kinase 8-interacting protein 4) (Proliferation-inducing protein 6) (Protein highly expressed in testis) (PHET) (Sperm surface protein) (Sperm-associated antigen 9) (Sperm-specific protein) (Sunday driver 1)SPAG9 HSS KIAA0516 MAPK8IP4 SYD1 HLC6O6027111
C-X-C chemokine receptor type 4 (CXC-R4) (CXCR-4) (FB22) (Fusin) (HM89) (LCR1) (Leukocyte-derived seven transmembrane domain receptor) (LESTR) (NPYRL) (Stromal cell-derived factor 1 receptor) (SDF-1 receptor) (CD antigen CD184)CXCR4P6107311
Calcium and integrin-binding protein 1 (CIB) (Calcium- and integrin-binding protein) (CIBP) (Calmyrin) (DNA-PKcs-interacting protein) (Kinase-interacting protein) (KIP) (SNK-interacting protein 2-28) (SIP2-28)CIB1 CIB KIP PRKDCIPQ9982811
Caldesmon (CDM)CALD1 CAD CDMQ0568211
Calpain-3 (EC (Calcium-activated neutral proteinase 3) (CANP 3) (Calpain L3) (Calpain p94) (Muscle-specific calcium-activated neutral protease 3) (New calpain 1) (nCL-1)CAPN3 CANP3 CANPL3 NCL1P2080711
Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin)CNN2Q9943911
Catalase (EC
CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)CD81 TAPA1 TSPAN28P6003311
CD82 antigen (C33 antigen) (IA4) (Inducible membrane protein R2) (Metastasis suppressor Kangai-1) (Suppressor of tumorigenicity 6 protein) (Tetraspanin-27) (Tspan-27) (CD antigen CD82)CD82 KAI1 SAR2 ST6 TSPAN27P2770111
CDC28 protein kinase regulatory subunit 1B, isoform CRA_b (cDNA, FLJ92030, Homo sapiens CDC28 protein kinase regulatory subunit 1B (CKS1B),mRNA)CKS1B hCG_1739274Q5T17811
Cell division cycle protein 123 homolog (Protein D123) (HT-1080) (PZ32)CDC123 C10orf7 D123O7579411
Cell division cycle protein 20 homolog (p55CDC)CDC20Q1283411
Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog)CPSF4 CPSF30 NAR NEB1O9563911
Clustered mitochondria protein homologCLUH KIAA0664O7515311
Codanin-1CDAN1 UNQ664/PRO1295Q8IWY911
Coronin-1B (Coronin-2)CORO1BQ9BR7611
Cyclin-dependent kinase 2-associated protein 1 (CDK2-associated protein 1) (Deleted in oral cancer 1) (DOC-1) (Putative oral cancer suppressor)CDK2AP1 CDKAP1 DOC1O1451911
Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1) (Melanoma differentiation-associated protein 6) (MDA-6) (p21)CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1P3893611
Cyclin-dependent kinases regulatory subunit 2 (CKS-2)CKS2P3355211
Cyclin-Y (Cyc-Y) (Cyclin box protein 1) (Cyclin fold protein 1) (cyclin-X)CCNY C10orf9 CBCP1 CFP1Q8ND7611
Cysteine--tRNA ligase, cytoplasmic (EC (Cysteinyl-tRNA synthetase) (CysRS)CARSP4958911
Cytochrome b-c1 complex subunit 6, mitochondrial (Complex III subunit 6) (Complex III subunit VIII) (Cytochrome c1 non-heme 11 kDa protein) (Mitochondrial hinge protein) (Ubiquinol-cytochrome c reductase complex 11 kDa protein)UQCRHP0791911
Cytochrome b-c1 complex subunit 8 (Complex III subunit 8) (Complex III subunit VIII) (Ubiquinol-cytochrome c reductase complex 9.5 kDa protein) (Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C)UQCRQO1494911
Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC (Complex III subunit 5) (Cytochrome b-c1 complex subunit 5) (Rieske iron-sulfur protein) (RISP) (Ubiquinol-cytochrome c reductase iron-sulfur subunit) [Cleaved into: Cytochrome b-c1 complex subunit 11 (Complex III subunit IX) (Ubiquinol-cytochrome c reductase 8 kDa protein)]UQCRFS1P4798511
Cytochrome c oxidase copper chaperoneCOX17Q1406111
D(1B) dopamine receptor (D(5) dopamine receptor) (D1beta dopamine receptor) (Dopamine D5 receptor)DRD5 DRD1B DRD1L2P2191811
D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC PGDH3O4317511
Death domain-associated protein 6 (Daxx) (hDaxx) (ETS1-associated protein 1) (EAP1) (Fas death domain-associated protein)DAXX BING2 DAP6Q9UER711
Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1-related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND domain-containing protein 5)DEAF1 SPN ZMYND5O7539811
Deoxynucleotidyltransferase terminal-interacting protein 2 (Estrogen receptor-binding protein) (LPTS-interacting protein 2) (LPTS-RP2) (Terminal deoxynucleotidyltransferase-interacting factor 2) (TdIF2) (TdT-interacting factor 2)DNTTIP2 ERBP TDIF2Q5QJE611
Developmentally-regulated GTP-binding protein 1 (DRG-1) (Neural precursor cell expressed developmentally down-regulated protein 3) (NEDD-3)DRG1 NEDD3Q9Y29511
Diamine acetyltransferase 1 (EC (Polyamine N-acetyltransferase 1) (Putrescine acetyltransferase) (Spermidine/spermine N(1)-acetyltransferase 1) (SSAT) (SSAT-1)SAT1 SATP2167311
DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD)DFFA DFF1 DFF45 H13O0027311
Double-strand-break repair protein rad21 homolog (hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog)RAD21 HR21 KIAA0078 NXP1O6021611
Drebrin-like protein (Cervical SH3P7) (Cervical mucin-associated protein) (Drebrin-F) (HPK1-interacting protein of 55 kDa) (HIP-55) (SH3 domain-containing protein 7)DBNL CMAP SH3P7 PP5423Q9UJU611
Dual specificity protein phosphatase 22 (EC (EC (JNK-stimulatory phosphatase-1) (JSP-1) (Low molecular weight dual specificity phosphatase 2) (LMW-DSP2) (Mitogen-activated protein kinase phosphatase x) (MAP kinase phosphatase x) (MKP-x)DUSP22 JSP1 LMWDSP2 MKPXQ9NRW411
Dual specificity protein phosphatase 23 (EC (EC (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z)DUSP23 LDP3 VHZQ9BVJ711
Dual specificity protein phosphatase 6 (EC (EC (Dual specificity protein phosphatase PYST1) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3)DUSP6 MKP3 PYST1Q1682811
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)DYRK1A DYRK MNB MNBHQ1362711
Dynactin subunit 5 (Dynactin subunit p25)DCTN5Q9BTE111
Dysbindin domain-containing protein 1DBNDD1Q9H9R911
Dystrobrevin alpha (DTN-A) (Alpha-dystrobrevin) (Dystrophin-related protein 3)DTNA DRP3Q9Y4J811
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