EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Histone H2A type 1-CHist1h2acC0HKE26
Histone H2A type 1-DHist1h2adC0HKE36
Histone H2A type 1-EHist1h2aeC0HKE46
Histone H2A type 1-GHist1h2agC0HKE56
Histone H2A type 1-IHist1h2aiC0HKE66
Histone H2A type 1-NHist1h2anC0HKE76
Histone H2A type 1-OHist1h2aoC0HKE86
Histone H2A type 1-PHist1h2apC0HKE96
Histone H2B type 3-BHist3h2bb Hist3h2bb-psQ8CGP06
Host cell factor 1 (HCF) (HCF-1) (C1 factor) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6]Hcfc1Q611916
Hsc70-interacting proteinSt13F8WJK86
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HCDH) (EC 1.1.1.35) (Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase) (Short-chain 3-hydroxyacyl-CoA dehydrogenase)Hadh Hadhsc Mschad SchadQ614256
Immunoglobulin superfamily member 8Igsf8G3UYZ16
Inactive peptidyl-prolyl cis-trans isomerase FKBP6 (Inactive PPIase FKBP6) (36 kDa FK506-binding protein) (36 kDa FKBP) (FKBP-36) (FK506-binding protein 6) (FKBP-6) (Immunophilin FKBP36)Fkbp6 Fkbp36Q91XW86
Inositol (Myo)-1(Or 4)-monophosphatase 1 (Inositol (Myo)-1(Or 4)-monophosphatase 1, isoform CRA_a) (Inositol monophosphatase 1) (Myo-inositol monophosphatase 1) (Putative uncharacterized protein)Impa1 mCG_1639Q924B06
Integrator complex subunit 11 (Int11) (EC 3.1.27.-) (Cleavage and polyadenylation-specific factor 3-like protein) (CPSF3-like protein)Ints11 Cpsf3lQ9CWS46
Integrator complex subunit 6 (Int6) (DBI-1) (Protein DDX26)Ints6 Dbi1 Ddx26Q6PCM26
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain]Itga7Q617386
Integrin betaItgb5Q6PE706
Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Serine/threonine-protein kinase TIK) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)Eif2ak2 Pkr Prkr TikQ039636
Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PKR-associated protein X) (PKR-associating protein X) (RAX) (Protein activator of the interferon-induced protein kinase) (Protein kinase, interferon-inducible double-stranded RNA-dependent activator)Prkra RaxQ9WTX26
Interferon-stimulated gene 20 kDa protein (EC 3.1.13.1) (Promyelocytic leukemia nuclear body-associated protein ISG20) (Protein DnaQL)Isg20Q9JL166
Isoleucine--tRNA ligase, mitochondrial (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS)Iars2Q8BIJ66
Isopentenyl-diphosphate Delta-isomerase 1 (EC 5.3.3.2) (Isopentenyl pyrophosphate isomerase 1) (IPP isomerase 1) (IPPI1)Idi1P580446
Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Type-II keratin Kb7)Krt7 Krt2-7Q9DCV76
Kinesin heavy chain isoform 5A (Kinesin heavy chain neuron-specific 1) (Neuronal kinesin heavy chain) (NKHC)Kif5a Kiaa4086 Kif5 Nkhc1P331756
Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2)Kif5c Nkhc2P287386
Kinesin-like protein KIF16BKif16b Kiaa1590B1AVY76
Kinesin-like protein KIF1CKif1cO350716
Kinesin-like protein KIF20B (Kinesin family member 20B) (Kinesin-related motor interacting with PIN1) (M-phase phosphoprotein 1) (MPP1)Kif20b Mphosph1Q80WE46
Kinesin-like protein KIF2C (Mitotic centromere-associated kinesin) (MCAK)Kif2cQ922S86
L-dopachrome tautomerase (DCT) (DT) (EC 5.3.3.12) (DOPAchrome conversion factor) (DOPAchrome isomerase) (DOPAchrome oxidoreductase) (L-dopachrome Delta-isomerase) (SLATY locus protein) (Tyrosinase-related protein 2) (TRP-2) (TRP2)Dct Tyrp-2 Tyrp2P298126
Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1)Lrch1 Chdc1 Kiaa1016P620466
Leucine-rich repeat and calponin homology domain-containing protein 3Lrch3Q8BVU06
Leucine-rich repeat protein SHOC-2 (Protein soc-2 homolog) (Protein sur-8 homolog)Shoc2O885206
LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN)Lima1 D15Ertd366e EplinQ9ERG06
Lipolysis-stimulated lipoprotein receptor (Lipolysis-stimulated receptor) (Liver-specific bHLH-Zip transcription factor) (Liver-specific gene on mouse chromosome 7 protein)Lsr Lisch7Q99KG56
Lipoma HMGIC fusion partnerLhfpQ8BM866
Liprin-beta-2 (Coiled-coil-like protein 1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2)Ppfibp2 Cclp1O357116
Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)Lrp2A2ARV46
Lysosomal Pro-X carboxypeptidase (EC 3.4.16.2) (Proline carboxypeptidase) (Prolylcarboxypeptidase) (PRCP)PrcpQ7TMR06
Lysyl oxidase homolog 2 (EC 1.4.3.13) (Lysyl oxidase-like protein 2)Loxl2P580226
Lysyl oxidase homolog 3 (EC 1.4.3.-) (EC 1.4.3.13) (Lysyl oxidase-like protein 3) (Lysyl oxidase-related protein 2)Loxl3 Lor2Q9Z1756
Macrophage mannose receptor 1 (MMR) (CD antigen CD206)Mrc1Q618306
Macrosialin (CD antigen CD68)Cd68P319966
Major facilitator superfamily domain-containing protein 1Mfsd1Q9DC376
Maleylacetoacetate isomerase (MAAI) (EC 5.2.1.2) (GSTZ1-1) (Glutathione S-transferase zeta 1) (EC 2.5.1.18)Gstz1 MaaiQ9WVL06
Mannose-1-phosphate guanyltransferase alpha (GDP-mannose pyrophosphorylase A) (GTP-mannose-1-phosphate guanylyltransferase alpha)GmppaQ922H46
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (EC 3.2.1.113) (Man(9)-alpha-mannosidase) (Man9-mannosidase) (Mannosidase alpha class 1A member 1) (Processing alpha-1,2-mannosidase IA) (Alpha-1,2-mannosidase IA)Man1a1 Man1aP457006
MCG140784 (Putative uncharacterized protein) (Trypsin 10) (Trypsinogen 10)Try10 Tcrb-V20 trypsinogen mCG_140784Q792Z16
Melan-AMlanaQ2TA506
Melanocyte protein PMEL (Putative uncharacterized protein) (Silver) (Silver, isoform CRA_a)Pmel Si mCG_18669Q9CZB26
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1)Magi1 Baiap1 Bap1Q6RHR96
Membrane-associated transporter protein (Melanoma antigen AIM1) (Protein AIM-1) (Protein underwhite) (Solute carrier family 45 member 2)Slc45a2 Aim1 Matp uwP583556
Metal transporter CNNM3 (Ancient conserved domain-containing protein 3) (mACDP3) (Cyclin-M3)Cnnm3 Acdp3Q32NY46
Metalloproteinase inhibitor 1 (Collagenase inhibitor 16C8 fibroblast) (Erythroid-potentiating activity) (EPA) (TPA-S1) (TPA-induced protein) (Tissue inhibitor of metalloproteinases 1) (TIMP-1)Timp1 Timp Timp-1P120326
Metalloreductase STEAP2 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 2)Steap2Q8BWB66
Metastasis-associated protein MTA1Mta1Q8K4B06
Metastasis-associated protein MTA1 (Metastasis-associated protein MTA1 isoform 2)Mta1F8WHY86
Methionine aminopeptidase 2 (MAP 2) (MetAP 2) (EC 3.4.11.18) (Initiation factor 2-associated 67 kDa glycoprotein) (p67) (p67eIF2) (Peptidase M)Metap2 Mnpep P67eif2O086636
Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18) (EC 1.2.1.27) (Aldehyde dehydrogenase family 6 member A1)Aldh6a1Q9EQ206
Microtubule-associated protein 1B (MAP-1B) (MAP1(X)) (MAP1.2) [Cleaved into: MAP1B heavy chain; MAP1 light chain LC1]Map1b Mtap1b Mtap5P148736
Microtubule-associated protein 1S (MAP-1S) (BPY2-interacting protein 1) (Microtubule-associated protein 8) [Cleaved into: MAP1S heavy chain; MAP1S light chain]Map1s Bpy2ip1 Map8 Mtap1sQ8C0526
Microtubule-associated proteins 1A/1B light chain 3A (Autophagy-related protein LC3 A) (Autophagy-related ubiquitin-like modifier LC3 A) (MAP1 light chain 3-like protein 1) (MAP1A/MAP1B light chain 3 A) (MAP1A/MAP1B LC3 A) (Microtubule-associated protein 1 light chain 3 alpha)Map1lc3aQ91VR76
Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta)Map1lc3b Map1alc3 Map1lc3Q9CQV66
Mitochondrial carrier homolog 2Mtch2Q791V56
Mitochondrial-processing peptidase subunit beta (EC 3.4.24.64) (Beta-MPP) (P-52)PmpcbQ9CXT86
MKI67 FHA domain-interacting nucleolar phosphoprotein (Nucleolar protein interacting with the FHA domain of pKI-67) (mNIFK)Nifk Mki67ipQ91VE66
Multidrug resistance-associated protein 5 (ATP-binding cassette sub-family C member 5) (Multi-specific organic anion transporter C) (MOAT-C) (SMRP)Abcc5 Abcc5a Mrp5Q9R1X56
Multiple PDZ domain protein (Multi-PDZ domain protein 1)Mpdz Mupp1Q8VBX66
MuskelinMkln1O890506
Myosin light chain 6B (Smooth muscle and nonmuscle myosin light chain alkali 6B)Myl6bQ8CI436
N-alpha-acetyltransferase 40 (EC 2.3.1.257) (N-acetyltransferase 11) (N-alpha-acetyltransferase D) (NatD) (Protein acetyltransferase 1)Naa40 Nat11 Patt1Q8VE106
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (Cell death regulatory protein GRIM-19) (Complex I-B16.6) (CI-B16.6) (Gene associated with retinoic and interferon-induced mortality 19 protein) (GRIM-19) (Gene associated with retinoic and IFN-induced mortality 19 protein) (NADH-ubiquinone oxidoreductase B16.6 subunit)Ndufa13 Grim19Q9ERS26
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (Complex I-19kD) (CI-19kD) (Complex I-PGIV) (CI-PGIV) (NADH-ubiquinone oxidoreductase 19 kDa subunit)Ndufa8Q9DCJ56
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (Complex I-PDSW) (CI-PDSW) (NADH-ubiquinone oxidoreductase PDSW subunit)Ndufb10Q9DCS96
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-51kD) (CI-51kD) (NADH-ubiquinone oxidoreductase 51 kDa subunit)Ndufv1Q91YT06
Nardilysin (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C) (Nardilysin convertase)Nrdc Nrd1Q8BHG16
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)Nedd8 Nedd-8P295956
NeogeninNeo1 NgnP977986
Nephronectin (Preosteoblast EGF-like repeat protein with MAM domain)Npnt Neph1 PoemQ91V886
Netrin receptor UNC5C (Protein unc-5 homolog 3) (Protein unc-5 homolog C) (Rostral cerebellar malformation protein)Unc5c Rcm Unc5h3O087476
Neurogenic locus notch homolog protein 2 (Notch gene homolog 2 (Drosophila), isoform CRA_a)Notch2 mCG_11101G5E8J06
Neuronal cell adhesion molecule (Nr-CAM) (Neuronal surface protein Bravo) (mBravo) (NgCAM-related cell adhesion molecule) (Ng-CAM-related)Nrcam Kiaa0343Q810U46
Neutral ceramidase (N-CDase) (NCDase) (EC 3.5.1.23) (Acylsphingosine deacylase 2) (N-acylsphingosine amidohydrolase 2) [Cleaved into: Neutral ceramidase soluble form]Asah2Q9JHE36
Nodal modulator 1Nomo1Q6GQT96
Nostrin (Disabled homolog 2-interacting protein 2) (Dab2-interacting protein 2) (Nitric oxide synthase trafficker) (eNOS-trafficking inducer)Nostrin Daip2Q6WKZ76
Nuclear mitotic apparatus protein 1Numa1E9Q7G06
Nuclear pore complex protein Nup85 (85 kDa nucleoporin) (FROUNT) (Nucleoporin Nup85) (Pericentrin-1)Nup85 Pcnt1Q8R4806
Nuclear pore glycoprotein p62 (62 kDa nucleoporin) (Nucleoporin Nup62)Nup62Q638506
Nucleolysin TIAR (TIA-1-related protein)Tial1P703186
Nucleoporin Nup43 (Nup107-160 subcomplex subunit Nup43)Nup43P592356
Nucleoprotein TPR (NPC-associated intranuclear protein) (Translocated promoter region and nuclear basket protein)TprF6ZDS46
NudC domain-containing protein 1Nudcd1Q6PIP56
Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor)OgfrQ99PG26
PaladinPald1 PaldP702616
Palmitoyl-protein thioesterase 1 (PPT-1) (EC 3.1.2.22) (Palmitoyl-protein hydrolase 1)Ppt1 Cln1 PptO885316
PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma)Pdlim7 EnigmaQ3TJD76
Pentraxin-related protein PTX3 (Pentaxin-related protein PTX3) (Tumor necrosis factor-inducible gene 14 protein) (TSG-14)Ptx3 Tsg14P487596
Peptidyl-prolyl cis-trans isomerase E (PPIase E) (EC 5.2.1.8) (Cyclophilin E) (Cyclophilin-33) (Rotamase E)Ppie Cyp33Q9QZH36
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