EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
Protein crumbs homolog 3CRB3 UNQ588/PRO1158Q9BUF711
Protein FAM115AFAM115A KIAA0738Q9Y4C211
Protein kinase C delta type (EC (Tyrosine-protein kinase PRKCD) (EC (nPKC-delta) [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit (Sphingosine-dependent protein kinase-1) (SDK1)]PRKCDQ0565511
Protein LSM12 homologLSM12Q3MHD211
Protein transport protein Sec61 subunit gammaSEC61GP6005911
Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial (EC (Endopeptidase Clp)CLPPQ1674011
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC (ATP-dependent RNA helicase #46) (DEAH box protein 15)DHX15 DBP1 DDX15O4314311
Ras-related protein Rab-6A (Rab-6)RAB6A RAB6P2034011
Ribonuclease inhibitor (Placental ribonuclease inhibitor) (Placental RNase inhibitor) (Ribonuclease/angiogenin inhibitor 1) (RAI)RNH1 PRI RNHP1348911
Ribosome biogenesis protein BRX1 homolog (Brix domain-containing protein 2)BRIX1 BRIX BXDC2Q8TDN611
RNA-binding motif protein, X chromosome (Glycoprotein p43) (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G) [Cleaved into: RNA-binding motif protein, X chromosome, N-terminally processed]RBMX HNRPG RBMXP1P3815911
RNA-binding protein PNO1PNO1Q9NRX111
RuvB-like 1 (EC (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)RUVBL1 INO80H NMP238 TIP49 TIP49AQ9Y26511
Serine protease HTRA1 (EC 3.4.21.-) (High-temperature requirement A serine peptidase 1) (L56) (Serine protease 11)HTRA1 HTRA PRSS11Q9274311
Serine/threonine-protein kinase Kist (EC (Kinase interacting with stathmin) (PAM COOH-terminal interactor protein 2) (P-CIP2) (U2AF homology motif kinase 1)UHMK1 KIS KISTQ8TAS111
Serine/threonine-protein kinase ULK1 (EC (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)ULK1 KIAA0722O7538511
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma (Protein phosphatase subunit G5PR) (Rhabdomyosarcoma antigen MU-RMS-40.6A/6C)PPP2R3C C14orf10 G5PRQ969Q611
Signal peptidase complex catalytic subunit SEC11A (EC (Endopeptidase SP18) (Microsomal signal peptidase 18 kDa subunit) (SPase 18 kDa subunit) (SEC11 homolog A) (SEC11-like protein 1) (SPC18)SEC11A SEC11L1 SPC18 SPCS4AP6781211
Signal recognition particle subunit SRP72 (SRP72) (Signal recognition particle 72 kDa protein)SRP72O7609411
Solute carrier family 25 member 39SLC25A39 CGI-69 PRO2163Q9BZJ411
Sorting and assembly machinery component 50 homolog (Transformation-related gene 3 protein) (TRG-3)SAMM50 CGI-51 SAM50 TRG3Q9Y51211
Spermidine synthase (SPDSY) (EC (Putrescine aminopropyltransferase)SRM SPS1 SRML1P1962311
StAR-related lipid transfer protein 7, mitochondrial (Gestational trophoblastic tumor protein 1) (START domain-containing protein 7) (StARD7)STARD7 GTT1Q9NQZ511
Stress-associated endoplasmic reticulum protein 1 (Ribosome-attached membrane protein 4)SERP1 RAMP4Q9Y6X111
Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial (EC (GTP-specific succinyl-CoA synthetase subunit beta) (Succinyl-CoA synthetase beta-G chain) (SCS-betaG)SUCLG2Q96I9911
Supervillin (Archvillin) (p205/p250)SVILO9542511
T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (hTRiC5)CCT3 CCTG TRIC5P4936811
Transcriptional enhancer factor TEF-3 (TEA domain family member 4) (TEAD-4) (Transcription factor 13-like 1) (Transcription factor RTEF-1)TEAD4 RTEF1 TCF13L1 TEF3Q1556111
Transcriptional repressor p66-alpha (Hp66alpha) (GATA zinc finger domain-containing protein 2A)GATAD2AQ86YP411
Transforming protein RhoA (Rho cDNA clone 12) (h12)RHOA ARH12 ARHA RHO12P6158611
Translocon-associated protein subunit delta (TRAP-delta) (Signal sequence receptor subunit delta) (SSR-delta)SSR4 TRAPDP5157111
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (EC (tRNA(m1A58)-methyltransferase subunit TRMT61A) (tRNA(m1A58)MTase subunit TRMT61A)TRMT61A C14orf172 TRM61Q96FX711
Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain)TUBB4B TUBB2CP6837111
Twinfilin-1 (Protein A6) (Protein tyrosine kinase 9)TWF1 PTK9Q1279211
Tyrosine-protein kinase Yes (EC (Proto-oncogene c-Yes) (p61-Yes)YES1 YESP0794711
Tyrosine-protein phosphatase non-receptor type 6 (EC (Hematopoietic cell protein-tyrosine phosphatase) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Protein-tyrosine phosphatase SHP-1) (SH-PTP1)PTPN6 HCP PTP1CP2935011
Ubiquitin-conjugating enzyme E2 D2 (EC (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1)UBE2D2 PUBC1 UBC4 UBC5B UBCH4 UBCH5BP6283711
Ubiquitin-conjugating enzyme E2 S (EC (E2-EPF) (Ubiquitin carrier protein S) (Ubiquitin-conjugating enzyme E2-24 kDa) (Ubiquitin-conjugating enzyme E2-EPF5) (Ubiquitin-protein ligase S)UBE2S E2EPF OK/SW-cl.73Q1676311
Ubiquitin-like modifier-activating enzyme 1 (Protein A1S9) (Ubiquitin-activating enzyme E1)UBA1 A1S9T UBE1P2231411
Uncharacterized membrane protein C19orf24C19orf24Q9BVV811
UPF0420 protein C16orf58C16orf58Q96GQ511
V-type proton ATPase subunit H (V-ATPase subunit H) (Nef-binding protein 1) (NBP1) (Protein VMA13 homolog) (V-ATPase 50/57 kDa subunits) (Vacuolar proton pump subunit H) (Vacuolar proton pump subunit SFD)ATP6V1H CGI-11Q9UI1211
Vacuolar fusion protein CCZ1 homolog B (Vacuolar fusion protein CCZ1 homolog-like)CCZ1B C7orf28BP8679011
Vacuolar protein sorting-associated protein 29 (hVPS29) (EC (PEP11 homolog) (Vesicle protein sorting 29)VPS29 DC15 DC7 MDS007Q9UBQ011
Vesicle-trafficking protein SEC22b (ER-Golgi SNARE of 24 kDa) (ERS-24) (ERS24) (SEC22 vesicle-trafficking protein homolog B) (SEC22 vesicle-trafficking protein-like 1)SEC22B SEC22L1O7539611
Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3)CACNB3 CACNLB3P5428411
Zinc finger protein 36, C3H1 type-like 1 (Butyrate response factor 1) (EGF-response factor 1) (ERF-1) (Protein TIS11B)ZFP36L1 BERG36 BRF1 ERF1 RNF162B TIS11BQ0735211
Zinc finger protein 765ZNF765Q7L2R611
26S protease regulatory subunit 4 (P26s4) (26S proteasome AAA-ATPase subunit RPT2) (Proteasome 26S subunit ATPase 1)PSMC1P6219110
26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5) (26S proteasome regulatory subunit p55)PSMD12O0023210
26S proteasome non-ATPase regulatory subunit 8 (26S proteasome regulatory subunit RPN12) (26S proteasome regulatory subunit S14) (p31)PSMD8P4855610
28S ribosomal protein S10, mitochondrial (MRP-S10) (S10mt)MRPS10 MSTP040P8266410
28S ribosomal protein S18b, mitochondrial (MRP-S18-b) (Mrps18-b) (S18mt-b) (28S ribosomal protein S18-2, mitochondrial) (MRP-S18-2)MRPS18B C6orf14 HSPC183 PTD017Q9Y67610
3-oxo-5-beta-steroid 4-dehydrogenase (EC (Aldo-keto reductase family 1 member D1) (Delta(4)-3-ketosteroid 5-beta-reductase) (Delta(4)-3-oxosteroid 5-beta-reductase)AKR1D1 SRD5B1P5185710
39S ribosomal protein L23, mitochondrial (L23mt) (MRP-L23) (L23 mitochondrial-related protein) (Ribosomal protein L23-like)MRPL23 L23MRP RPL23LQ1654010
39S ribosomal protein L27, mitochondrial (L27mt) (MRP-L27)MRPL27 HSPC250Q9P0M910
40S ribosomal protein S17-likeRPS17LP0CW2210
40S ribosomal protein S8RPS8 OK/SW-cl.83P6224110
40S ribosomal protein SA (37 kDa laminin receptor precursor) (37LRP) (37/67 kDa laminin receptor) (LRP/LR) (67 kDa laminin receptor) (67LR) (Colon carcinoma laminin-binding protein) (Laminin receptor 1) (LamR) (Laminin-binding protein precursor p40) (LBP/p40) (Multidrug resistance-associated protein MGr1-Ag) (NEM/1CHD4)RPSA LAMBR LAMR1P0886510
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (6PF-2-K/Fru-2,6-P2ase 3) (PFK/FBPase 3) (6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme) (Renal carcinoma antigen NY-REN-56) (iPFK-2) [Includes: 6-phosphofructo-2-kinase (EC; Fructose-2,6-bisphosphatase (EC]PFKFB3Q1687510
60S ribosomal protein L30RPL30P6288810
60S ribosomal protein L39RPL39P6289110
A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47)AKAP13 BRX HT31 LBCQ1280210
A-kinase anchor protein 8 (AKAP-8) (A-kinase anchor protein 95 kDa) (AKAP 95)AKAP8 AKAP95O4382310
Activating signal cointegrator 1 complex subunit 1 (ASC-1 complex subunit p50) (Trip4 complex subunit p50)ASCC1 CGI-18Q8N9N210
Activin receptor type-1B (EC (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)ACVR1B ACVRLK4 ALK4P3689610
Adapter molecule crk (Proto-oncogene c-Crk) (p38)CRKP4610810
ADP/ATP translocase 1 (ADP,ATP carrier protein 1) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) (Adenine nucleotide translocator 1) (ANT 1) (Solute carrier family 25 member 4)SLC25A4 ANT1P1223510
Aldehyde dehydrogenase family 1 member A3 (EC (Aldehyde dehydrogenase 6) (Retinaldehyde dehydrogenase 3) (RALDH-3) (RalDH3)ALDH1A3 ALDH6P4789510
Alpha-2 globin chain (Delta globin) (HCG1745306, isoform CRA_b)HBA2 hCG_1745306D1MGQ210
Amyloid beta A4 precursor protein-binding family A member 3 (Adapter protein X11gamma) (Neuron-specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3)APBA3 MINT3 X11L2O9601810
AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216)ZFAND5 ZA20D2 ZNF216O7608010
AP-3 complex subunit beta-1 (Adapter-related protein complex 3 subunit beta-1) (Adaptor protein complex AP-3 subunit beta-1) (Beta-3A-adaptin) (Clathrin assembly protein complex 3 beta-1 large chain)AP3B1 ADTB3AO0020310
Apoptosis inhibitor 5 (API-5) (Antiapoptosis clone 11 protein) (AAC-11) (Cell migration-inducing gene 8 protein) (Fibroblast growth factor 2-interacting factor) (FIF) (Protein XAGL)API5 MIG8Q9BZZ510
Arginine/serine-rich protein PNISR (PNN-interacting serine/arginine-rich protein) (SR-related protein) (SR-rich protein) (Serine/arginine-rich-splicing regulatory protein 130) (SRrp130) (Splicing factor, arginine/serine-rich 130) (Splicing factor, arginine/serine-rich 18)PNISR C6orf111 SFRS18 SRRP130 HSPC261 HSPC306Q8TF0110
Asparagine--tRNA ligase, cytoplasmic (EC (Asparaginyl-tRNA synthetase) (AsnRS)NARSO4377610
Aspartate aminotransferase, mitochondrial (mAspAT) (EC (EC (Fatty acid-binding protein) (FABP-1) (Glutamate oxaloacetate transaminase 2) (Kynurenine aminotransferase 4) (Kynurenine aminotransferase IV) (Kynurenine--oxoglutarate transaminase 4) (Kynurenine--oxoglutarate transaminase IV) (Plasma membrane-associated fatty acid-binding protein) (FABPpm) (Transaminase A)GOT2P0050510
ATM interactor (ATM/ATR-substrate CHK2-interacting zinc finger protein) (ASCIZ) (Zinc finger protein 822)ATMIN KIAA0431 ZNF822O4331310
ATP-binding cassette sub-family E member 1 (2'-5'-oligoadenylate-binding protein) (HuHP68) (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I)ABCE1 RLI RNASEL1 RNASELI RNS4I OK/SW-cl.40P6122110
ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC transporter 2)ABCF2 HUSSY-18Q9UG6310
Aurora kinase B (EC (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)AURKB AIK2 AIM1 AIRK2 ARK2 STK1 STK12 STK5Q96GD410
Bcl2 antagonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl-2-like protein 8) (Bcl2-L-8) (Bcl-XL/Bcl-2-associated death promoter)BAD BBC6 BCL2L8Q9293410
Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR transformylase); IMP cyclohydrolase (EC (ATIC) (IMP synthase) (Inosinicase)]ATIC PURH OK/SW-cl.86P3193910
Brain acid soluble protein 1 (22 kDa neuronal tissue-enriched acidic protein) (Neuronal axonal membrane protein NAP-22)BASP1 NAP22P8072310
C-C motif chemokine 3-like 1 (G0/G1 switch regulatory protein 19-2) (LD78-beta(1-70)) (PAT 464.2) (Small-inducible cytokine A3-like 1) (Tonsillar lymphocyte LD78 beta protein) [Cleaved into: LD78-beta(3-70); LD78-beta(5-70)]CCL3L1 D17S1718 G0S19-2 SCYA3L1; CCL3L3P1661910
C-Maf-inducing protein (c-Mip) (Truncated c-Maf-inducing protein) (Tc-Mip)CMIP KIAA1694 TCMIPQ8IY2210
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)CANXP2782410
cAMP-dependent protein kinase type II-alpha regulatory subunitPRKAR2A PKR2 PRKAR2P1386110
Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC
Caspase-4 (CASP-4) (EC (ICE(rel)-II) (Protease ICH-2) (Protease TX) [Cleaved into: Caspase-4 subunit 1; Caspase-4 subunit 2]CASP4 ICH2P4966210
CD2 antigen cytoplasmic tail-binding protein 2 (CD2 cytoplasmic domain-binding protein 2) (CD2 tail-binding protein 2) (U5 snRNP 52K protein) (U5-52K)CD2BP2 KIAA1178O9540010
Cdc42 effector protein 3 (Binder of Rho GTPases 2) (MSE55-related Cdc42-binding protein)CDC42EP3 BORG2 CEP3Q9UKI210
Cdc42 effector protein 5 (Binder of Rho GTPases 3)CDC42EP5 BORG3 CEP5Q6NZY710
Centrin-2 (Caltractin isoform 1)CETN2 CALT CEN2P4120810
Charged multivesicular body protein 2b (CHMP2.5) (Chromatin-modifying protein 2b) (CHMP2b) (Vacuolar protein sorting-associated protein 2-2) (Vps2-2) (hVps2-2)CHMP2B CGI-84Q9UQN310
Chloride intracellular channel protein 1 (Chloride channel ABP) (Nuclear chloride ion channel 27) (NCC27) (Regulatory nuclear chloride ion channel protein) (hRNCC)CLIC1 G6 NCC27O0029910
Cholinephosphotransferase 1 (hCPT1) (EC (AAPT1-like protein) (Diacylglycerol cholinephosphotransferase 1)CHPT1 CPT1 MSTP022Q8WUD610
Chromatin target of PRMT1 protein (Friend of PRMT1 protein) (Small arginine- and glycine-rich protein) (SRAG)CHTOP C1orf77 FOP HT031 PP7704Q9Y3Y210
Chromodomain-helicase-DNA-binding protein 1-like (EC (Amplified in liver cancer protein 1)CHD1L ALC1Q86WJ110
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