EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
50S ribosomal protein L3rplC PA4263Q9HWD58
50S ribosomal protein L3rplC EcE24377A_3803A7ZSK98
50S ribosomal protein L5rplE PA4251Q9HWE78
50S ribosomal protein L9rplI EcE24377A_4764A7ZV748
Acyl-homoserine lactone acylase QuiP (AHL acylase QuiP) (Acyl-HSL acylase QuiP) (EC (Quorum signal utilization and inactivation protein) [Cleaved into: Acyl-homoserine lactone acylase QuiP subunit alpha (Acyl-HSL acylase QuiP subunit alpha); Acyl-homoserine lactone acylase QuiP subunit beta (Acyl-HSL acylase QuiP subunit beta)]quiP PA1032Q9I4U28
Adenylate kinase (AK) (EC (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)adk ECRM12581_1800A0A023YSY58
ADP-heptose--LPS heptosyltransferase (ADP-heptose--LPS heptosyltransferase 2)rfaF A4T40_25495 BMT97_03750 ECONIH1_21135 MS6198_41640A0A023LJN88
AfeA (Periplasmic metal binding protein)Asd1617_01930 SD1617_5426E2XHV68
Alkyl hydroperoxide reductase subunit CahpC PA0139Q9I6Z38
Aminopeptidase (EC (Leucine aminopeptidase) (PaAP) [Cleaved into: Aminopeptidase AP58; Aminopeptidase AP56; Aminopeptidase AP28]lap PA2939Q9HZQ88
Aspartate carbamoyltransferase (EC (Aspartate transcarbamylase) (ATCase)pyrB PA0402Q596538
Aspartate carbamoyltransferase regulatory chainpyrI EcE24377A_4817A7ZVC68
Aspartate--tRNA(Asp/Asn) ligase (EC (Aspartyl-tRNA synthetase) (AspRS) (Non-discriminating aspartyl-tRNA synthetase) (ND-AspRS)aspS PA0963Q514228
ATP synthase epsilon chain (ATP synthase F1 sector epsilon subunit) (F-ATPase epsilon subunit)atpC PA5553Q9HT218
ATP-binding protein (ATP-binding protein in pho regulon) (Nucleoside triphosphate hydrolase) (PhoH-like heat shock protein) (PhoH-like protein) (PhoH-like protein YbeZ) (Putative ATP-binding protein in pho regulon)ybeZ ybeZ_2 AC789_1c06990 ACN002_0678 ACN77_23720 ACN81_03060 ACN87_03680 AWP75_10510 BE932_26900 BE949_13830 BE957_21460 BE963_17455 BN17_04471 BUE81_17215 BUE82_17395 BV389_16590 BW690_14795 BWP17_23160 BXT93_06735 EC3234A_6c00790 ECs0698 EL75_3122 EL79_3216 EL80_3172 ERS085365_02548 ERS085374_02545 ERS085379_01988 ERS085383_02849 ERS085386_01812 ERS085404_03444 ERS085406_01635 ERS085416_02401 ERS139211_01296 ERS139235_02751 ERS150876_03463 MS6198_07160 SM09_01473C3TJ628
ATP-dependent protease ATPase subunit HslU (Heat shock protein HslU) (Unfoldase HslU)hslU EcE24377A_4467A7ZUE68
Bacterioferritin (BFR) (EC (Cytochrome b-1) (Cytochrome b-557)bfr c4107P0ABD48
Bacterioferritin (EC PA3531Q9HY798
Beta-D-glucoside glucohydrolaseBX51_14725A0A025CER48
Carbamoyl-phosphate synthase large chain (EC (Carbamoyl-phosphate synthetase ammonia chain)carB PA4756P381008
Catalase (EC PA4236O527628
Citrate synthase (EC PA1580P141658
CysB family transcriptional regulator (HTH-type transcriptional regulator CysB) (LysR family transcriptional regulator CysB) (Transcriptional regulator CysB)cysB cysB_1 A4T40_10665 BK248_06570 BK334_00215 ECONIH1_07750 MS6198_15010A0A0A1A3E18
Cytosol aminopeptidase (EC (Aminopeptidase A/I) (Leucine aminopeptidase) (LAP) (EC (Leucyl aminopeptidase)pepA carP xerB Z5872 ECs5237P687688
D-xylose transporter subunit XylFxylF BX06_21090A0A028ATS08
Dihydroorotase-like protein (Aspartate carbamoyltransferase 44 kDa non-catalytic chain)pyrC' pyrX PA0401Q515518
DNA-binding transcriptional regulator KdgR (Transcriptional regulator)BE932_04620 SY51_10135A0A061KV388
Electron transfer flavoprotein subunit alpha (Alpha-ETF) (Electron transfer flavoprotein large subunit) (ETFLS)etfA PA2951Q9HZP78
Electron transfer flavoprotein-ubiquinone oxidoreductase (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase)PA2953Q9HZP58
Fatty acid oxidation complex subunit alpha [Includes: Enoyl-CoA hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase/3-hydroxybutyryl-CoA epimerase (EC (EC (EC; 3-hydroxyacyl-CoA dehydrogenase (EC]fadB PA3014Q9HZJ28
Fe(III) dicitrate transport protein FecAfecA PA3901Q9HXB28
Flagellar hook-associated protein 1 FlgKflgK PA1086Q9I4P38
Fructose-bisphosphate aldolase (FBP aldolase) (FBPA) (EC (Fructose-1,6-bisphosphate aldolase)fba fda PA0555Q9I5Y18
Gamma-aminobutyraldehyde dehydrogenase (EC (1-pyrroline dehydrogenase) (4-aminobutanal dehydrogenase) (ABALDH)prr BE932_02835 SY51_08460A0A061KCV18
Glutamate-1-semialdehyde 2,1-aminomutase (GSA) (EC (Glutamate-1-semialdehyde aminotransferase) (GSA-AT)hemL BE932_23905 SY51_00900A0A061KSA68
Glutarate-semialdehyde dehydrogenase DavD (EC PA0265Q9I6M58
Glycine-glutamate dipeptide porin OpdPopdP PA4501Q9HVS08
High affinity Fe+2 binding protein periplasmic component (Iron transporter) (Pathogen-specific membrane antigen)tpd A4T50_27810 APT94_27730 BE932_00970 BE957_01975 BE963_00450 BMT94_24895 ERS150873_04772 HMPREF3040_02885 IPF_124 pEC14_9 SM09_05297 SY51_26985 WM48_25140B1VCI28
HydrolaseBE932_04875 BK248_21350 SY51_10365A0A061YJU18
Hypothetical lipoprotein YajGyajG UTI89_C0458Q1RFA58
Leucine-responsive regulatory proteinlrp Z1234 ECs0974P0ACJ28
Lipoprotein (Putative lipoprotein YbjP)ybjP A4T40_08070 AC067_07620 AKG99_05730 AML35_15810 BE963_18610 BHF46_13955 BK248_26195 BK334_18440 BK375_04150 BV389_03425 BXT93_05125 ECONIH1_05150 ERS085366_01034 ERS085383_00499 ERS085386_04592 ERS085404_00571 JD73_09460 MS6198_09910 UC41_23080 UN91_20985A0A023KVV68
Membrane protein (Porin OmpA)BE932_29010 BK248_04040 SY51_05380A0A061YKB88
Membrane protein insertase YidC (Foldase YidC) (Membrane integrase YidC) (Membrane protein YidC)yidC PA5568Q9HT068
MvaT (Transcriptional regulator MvaT, P16 subunit)mvaT PA4315Q9HW868
Na(+)-translocating NADH-quinone reductase subunit C (Na(+)-NQR subunit C) (Na(+)-translocating NQR subunit C) (EC (NQR complex subunit C) (NQR-1 subunit C)nqrC PA2997Q9HZK88
Outer membrane lipoprotein SlyBslyB Z2655 ECs2350P0A9068
Penicillin-binding protein activator LpoB (PBP activator LpoB)lpoB BE932_29735 SY51_06090A0A061YHG58
Peptidase B (EC (Aminopeptidase B)pepB BE932_10425 SY51_14500A0A061YLR78
Peptidase M15UN91_20830A0A0F3TZY88
Peptide chain release factor 2 (RF-2)prfB E2348C_3144B7UHU08
Periplasmic trehalase (EC (Alpha,alpha-trehalase) (Alpha,alpha-trehalose glucohydrolase)treA BE932_30505 SY51_06835A0A066T1818
Phosphate-binding protein PstSpstS CE10_4369A0A0E0VCW78
Phosphoglycerate kinase (EC EcE24377A_3254A7ZR348
Plasminogen-binding protein PgbApgbA jhp_0458Q9ZLW88
Probable ATP-binding component of ABC transporterPA3187Q9HZ518
Probable peptidasePA2973Q9HZN18
Protein translocase subunit SecDsecD PA3821Q9HXI18
Putative beta-lactamase HcpC (EC (Cysteine-rich protein C)hcpC jhp_1024Q9ZKB58
Pyroglutatmate porin OpdOopdO PA2113Q9I2028
Pyruvate kinase (EC PA4329Q9HW728
Ribonuclease PH (RNase PH) (EC (tRNA nucleotidyltransferase)rph EcE24377A_4144A7ZTJ48
Ribose-5-phosphate isomerase A (EC (Phosphoriboisomerase A) (PRI)rpiA Ec53638_3004A0A0E1T6X38
RNA-binding protein Hfqhfq EcE24377A_4730A7ZV418
Serine protease MucDmucD PA0766G3XD208
Sigma factor-binding protein Crlcrl EcE24377A_0272A7ZHZ98
Signal recognition particle receptor FtsY (SRP receptor)ftsY BE932_16285 SY51_19775A0A061K6058
Transcription termination/antitermination protein NusAnusA Z4530 ECs4050P0AFF88
Transketolase (EC PA0548Q9I5Y88
Uncharacterized proteinPA2800Q9I0438
Uncharacterized proteinPA1011Q9I4W28
Uncharacterized proteinPA4495Q9HVS68
Uncharacterized proteinPA5232Q9HTV88
Uncharacterized proteinPA3822Q9HXI08
Uncharacterized proteinPA4441Q9HVX48
Uncharacterized proteinBX52_23975A0A0E2U7P58
Uncharacterized proteinBE932_09365A0A066T8X68
UPF0192 protein PA4489PA4489Q9HVT28
UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A)uvrA BE932_19885 SY51_23380A0A061L2L28
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC (Tetrahydrodipicolinate N-succinyltransferase) (THDP succinyltransferase) (THP succinyltransferase) (Tetrahydropicolinate succinylase)dapD E2348C_0171B7UIL17
2-oxoglutarate dehydrogenase (2-oxoglutarate dehydrogenase subunit E1)BE932_27270 SY51_03690A0A066T2A47
2-oxoisovalerate dehydrogenase subunit alpha (EC (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha)bkdA1 PA2247Q9I1M27
30S ribosomal protein S1rpsA Z1257 ECs0994P0AG697
30S ribosomal protein S10rpsJ PA4264Q9HWD47
30S ribosomal protein S16rpsP PA3745Q9HXP97
30S ribosomal protein S16rpsP EcE24377A_2893A7ZQ497
30S ribosomal protein S17rpsQ PA4254Q9HWE47
30S ribosomal protein S5rpsE CKO_04716A8AQJ87
30S ribosomal protein S7rpsG BWG_3032C4ZUJ67
50S ribosomal protein L15rplO PA4244Q9HWF47
50S ribosomal protein L17rplQ PA4237O527617
50S ribosomal protein L20rplT PA2741Q9I0A27
50S ribosomal protein L21rplU EcE24377A_3671A7ZS837
50S ribosomal protein L22rplV PA4258Q9HWE07
50S ribosomal protein L30rpmD EcE24377A_3785A7ZSJ17
50S ribosomal protein L31rpmE EcE24377A_4472A7ZUF17
50S ribosomal protein L5rplE EcE24377A_3791A7ZSJ77
50S ribosomal protein L9rplI PA4932Q9HUN27
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