EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
30S ribosomal protein S6rpsF NGO0581Q5F9254
30S ribosomal protein S6rpsF ECUMN_4733B7NGD44
30S ribosomal protein S7rpsG NGO1844Q5F5S24
30S ribosomal protein S7rpsG LMRG_02200A0A0H3GFF74
30S ribosomal protein S8rpsH NGO1826Q5F5U14
30S ribosomal protein S9rpsI NGO2025Q5F5A44
4-hydroxy-tetrahydrodipicolinate reductase (HTPA reductase) (EC PA4759P381034
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTA/SAH nucleosidase) (MTAN) (EC (5'-methylthioadenosine nucleosidase) (MTA nucleosidase) (S-adenosylhomocysteine nucleosidase) (AdoHcy nucleosidase) (SAH nucleosidase) (SRH nucleosidase)mtnN NGO_0345Q5F9P84
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTA/SAH nucleosidase) (MTAN) (EC (5'-methylthioadenosine nucleosidase) (MTA nucleosidase) (S-adenosylhomocysteine nucleosidase) (AdoHcy nucleosidase) (SAH nucleosidase) (SRH nucleosidase)mtnN Ec53638_1151A0A0E1T5934
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC (Cobalamin-independent methionine synthase) (Methionine synthase, vitamin-B12 independent isozyme)metE NGO0928Q5F8634
50S ribosomal protein L1rplA APU18_12880 BE932_19370 ERS085406_04587 ERS085411_00351 SY51_22895A0A061YFJ44
50S ribosomal protein L10rplJ NGO1853Q5F5R34
50S ribosomal protein L11rplK NGO1855Q5F5R14
50S ribosomal protein L13rplM NGO2024Q5F5A54
50S ribosomal protein L13rplM PA4433Q9HVY24
50S ribosomal protein L14rplN NGO1829Q5F5T74
50S ribosomal protein L15rplO NGO1823Q5F5U64
50S ribosomal protein L15rplO CKO_04713A8AQJ54
50S ribosomal protein L16rplP NGO1831.1 NGO18311Q5F5T44
50S ribosomal protein L17rplQ NGO1817Q5F5V34
50S ribosomal protein L18rplR NGO1824.1Q5F5U34
50S ribosomal protein L19rplS NGO0171Q5FA604
50S ribosomal protein L19rplS EcE24377A_2890A7ZQ464
50S ribosomal protein L2rplB NGO1835Q5F5T04
50S ribosomal protein L20rplT NGO0298Q5F9U14
50S ribosomal protein L21rplU NGO1676Q5F6864
50S ribosomal protein L21rplU LMRG_01428A0A0H3GH484
50S ribosomal protein L22rplV NGO1833Q5F5T24
50S ribosomal protein L24rplX PA4252Q9HWE64
50S ribosomal protein L25 (General stress protein CTC)rplY ctc NGO0442Q5F9F44
50S ribosomal protein L28rpmB NGO1680Q5F6824
50S ribosomal protein L29rpmC PA4255Q9HWE34
50S ribosomal protein L3rplC NGO1838Q5F5S74
50S ribosomal protein L3 glutamine methyltransferase (L3 MTase) (EC (N5-glutamine methyltransferase PrmB)prmB AKG99_12340 APT94_13835 BE949_08905 BE957_11365 BE963_27470 BIQ85_13295 BK248_00615 BK383_00015 BMT94_11045 BMT97_08730 BUE82_06880 BV389_03070 BXT93_09920 ERS139235_00403 HMPREF3040_00891 SM09_02498 UN91_13490A0A066R1F64
50S ribosomal protein L30rpmD NGO1823.1 NGO18231Q5F5U54
50S ribosomal protein L34rpmH NGO2182Q5F4W24
50S ribosomal protein L35rpmI NGO0297Q5F9U24
50S ribosomal protein L4rplD NGO1837Q5F5S84
50S ribosomal protein L5rplE NGO1827Q5F5T94
50S ribosomal protein L6rplF NGO1825Q5F5U24
50S ribosomal protein L7/L12rplL NGO1852Q5F5R44
50S ribosomal protein L9rplI NGO0584Q5F9224
6,7-dimethyl-8-ribityllumazine synthase (DMRL synthase) (LS) (Lumazine synthase) (EC NGO0257Q5F9X94
6-N-hydroxylaminopurine resistance proteinyiiM PGD_03119A0A024L6P04
60 kDa chaperonin (63 kDa stress protein) (GSP63) (GroEL protein) (HSP60) (Protein Cpn60)groL groEL hsp63 mopA NMB1972P423854
60 kDa chaperonin (GroEL protein) (Protein Cpn60)groL groEL mopA b4143 JW4103P0A6F54
60 kDa chaperonin (GroEL protein) (Protein Cpn60)groL groEL NGO2095Q5F5414
60 kDa chaperonin (GroEL protein) (Protein Cpn60)groL groEL Smlt4214B2FIU94
60 kDa chaperonin (GroEL protein) (Protein Cpn60)groL groEL LMRG_01218A0A0H3GLZ04
ABC transport systemLMRG_00840A0A0H3GBZ44
ABC transporterNGO_2121Q5F5184
ABC transporter ATP-binding proteinNGO_1573Q5F6I54
ABC transporter ATP-binding proteinNGO_0764Q5F8K84
ABC transporter substrate-binding proteinNGO_1152Q5F7L84
ABC transporter substrate-binding proteinNGO_2056Q5F5744
ABC transporter substrate-binding proteinNGO_2014Q5F5B54
ABC transporter substrate-binding proteinNGO_0168Q5FA634
ABC transporter substrate-binding proteinNGO_1440Q5F6V54
ABC transporter substrate-binding protein-oligopeptide transportamiA spr1707Q8DNI14
ABC transporter substrate-binding protein-sugar transportABC-SBP spr1527Q8DNU84
ABC-2 type transport system ATP-binding proteinLMRG_01330A0A0H3GGP84
Acetate kinase (EC (Acetokinase)ackA NGO_0977Q5F8244
Acetolactate synthase (EC
Acetyl-CoA carboxylase (Acetyl-CoA carboxylase biotin carboxylase subunit) (EC BE932_15175 SY51_18685 WM48_18040A0A067HC324
Acetyl-CoA carboxylase (EC
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha (ACCase subunit alpha) (Acetyl-CoA carboxylase carboxyltransferase subunit alpha) (EC NGO0821Q5F8F54
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase subunit beta) (Acetyl-CoA carboxylase carboxyltransferase subunit beta) (EC NGO_0249Q5F9Y54
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase subunit beta) (Acetyl-CoA carboxylase carboxyltransferase subunit beta) (EC EcE24377A_2610A7ZPD14
Acetyltransferase (N-acetyltransferase)BE932_14680 SY51_18205A0A066SQ504
Acetyltransferase component of pyruvate dehydrogenase complex (EC
Aconitate hydratase B (EC (EC (2-methylisocitrate dehydratase)NGO_1231Q5F7E74
Acyl carrier protein (ACP)acpP NGO1762Q5F6044
Acyl carrier protein 1 (ACP 1)acpP1 acpP PA2966O544394
Acyl-CoA thioesterase (Acyl-CoA thioesterase II)AUQ13_18240 BET08_25860 BK337_01765 BUE81_06485 UN91_18400A0A066QW624
Acyl-CoA thioesterase I (Multifunctional acyl-CoA thioesterase 1 and protease I and lysophospholipase L1) (EC (EC 3.1.2.-) (Multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1)tesA EC3234A_4c01620 ERS085365_02339 ERS085366_04291 ERS085374_02271 ERS085379_01104 ERS085386_01215 ERS085416_01865 ERS139211_01980 ERS139235_01657 ERS150873_01755 ERS150876_00673 SK85_00518 SM09_01285A0A090LDD54
Adenylosuccinate lyase (ASL) (EC (Adenylosuccinase)NGO_1711Q5F6554
Adenylosuccinate synthetase (AMPSase) (AdSS) (EC (IMP--aspartate ligase)purA NGO0398Q5F9J54
Adhesin MafA 1/4mafA1 NGO1067; mafA4 NGO1972Q5F5F64
Adhesin MafA 2/3mafA2 NGO1393; mafA3 NGO1584Q5F6H44
Adhesin/virulence factor HekhekQ93LE34
Aerotaxis receptor Aeraer PA1561Q9I3F64
Agmatinase (EC (Agmatine ureohydrolase) (AUH)speB NGO1486Q5F6R34
Alanine--tRNA ligase (EC (Alanyl-tRNA synthetase) (AlaRS)alaS NGO1254Q5F7C44
Aldehyde dehydrogenase (Aldehyde dehydrogenase B) (Lactaldehyde dehydrogenase) (EC 1.2.1.-)aldB A4T50_12230 A5958_10990 A9R57_20180 AA102_10090 AC789_1c39650 ACN77_01320 ACN81_12100 ACU90_14860 AM270_16210 AML07_21740 APZ14_23720 BE957_04300 BE963_09080 BHS81_21450 BHS87_20140 BJJ90_00640 BK248_14995 BK251_16245 BK292_09470 BMT49_23465 BMT61_11795 BMT97_18580 ERS085365_04047 ERS085374_04287 ERS085379_02911 ERS085416_01753 ERS139211_03752 ERS150873_04213 ERS150876_01984 FORC28_0193 GJ11_23030 GJ12_22350 HW42_22770 PU06_09810 RG28_23100 UN86_17935 WM48_19810 WQ89_12995A0A061K0L84
Altronate oxidoreductase (EC (Tagaturonate dehydrogenase) (Tagaturonate reductase)uxaB BY96_02090A0A027U5754
Amino acid ABC transporter permeaseNGO_2011Q5F5B84
Amino acid ABC transporter substrate-binding proteinNGO_0372Q5F9M14
Amino acid ABC transporter, periplasmic amino acid-binding proteinNMB0787Q9K0354
Amino acid ABC transporter, periplasmic amino acid-binding proteinNMB1612Q9JYF04
Amino acid ABC transporter, periplasmic binding protein (YckK)HP_0940O255944
Aminobenzoate synthetaseNGO_2112Q5F5254
Aminomethyltransferase (EC (Glycine cleavage system T protein)gcvT EcSMS35_3037B1LDA54
Aminopeptidase NpepN PA3083Q9HZC54
Aminotransferase (EC 2.6.1.-)NGO_1452Q5F6U34
Anthranilate phosphoribosyltransferase (EC NGO1203Q5F7H54
Anti-adapter protein IraPiraP EcE24377A_0409A7ZID14
Apolipoprotein N-acyltransferase (ALP N-acyltransferase) (EC 2.3.1.-) (Copper homeostasis protein CutE homolog)lnt cutE PA3984Q9ZI864
Arabinose 5-phosphate isomerase (API) (EC UN86_15350A0A0F3T3G64
Arginine ABC transporter substrate-binding proteinBE932_28015 SY51_04420A0A061KUD74
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