EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
Phosphopantetheine adenylyltransferase (EC (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase) (PPAT)coaD BE932_17360 SY51_20725A0A066T28110
Protease subunit HflKhflK PA4942Q9HUM210
Protein TolBtolB PA0972P5060110
Ribonucleoside-diphosphate reductase (EC PA1156Q9I4I110
Ribose-phosphate pyrophosphokinase (RPPK) (EC (5-phospho-D-ribosyl alpha-1-diphosphate) (Phosphoribosyl diphosphate synthase) (Phosphoribosyl pyrophosphate synthase) (P-Rib-PP synthase) (PRPP synthase) (PRPPase)prs PA4670Q9HVC510
Soluble pyridine nucleotide transhydrogenase (STH) (EC (NAD(P)(+) transhydrogenase [B-specific])sthA sth PA2991P5711210
Superoxide dismutase (EC SY51_22270A0A066T5B710
Thymidylate synthase (TS) (TSase) (EC EcE24377A_3147A7ZQT310
Uncharacterized proteinPA4426Q9HVY910
Uncharacterized proteinPA3729Q9HXR310
UPF0312 protein PA0423PA0423Q9I69010
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (BPG-dependent PGAM) (PGAM) (Phosphoglyceromutase) (dPGM) (EC EcE24377A_0782A7ZJD09
3-ketoacyl-CoA thiolase (EC (Acetyl-CoA acyltransferase) (Beta-ketothiolase) (Fatty acid oxidation complex subunit beta)fadA PA3013Q9HZJ39
3-oxoacyl-[acyl-carrier-protein] synthase 1 (EC (3-oxoacyl-[acyl-carrier-protein] synthase I) (Beta-ketoacyl-ACP synthase I) (KAS I)fabB c2869P0A9549
30S ribosomal protein S7rpsG PA4267Q9HWD19
33 kDa chaperonin (Heat shock protein 33 homolog) (HSP33)hslO BX52_10190A0A0E2U4A59
5-aminovalerate aminotransferase DavT (EC (5-aminovalerate transaminase) (Delta-aminovalerate aminotransferase)davT PA0266Q9I6M49
50S ribosomal protein L17rplQ EcE24377A_3777A7ZSI39
50S ribosomal protein L28 (LSU ribosomal protein L28p) (Ribosomal protein L28)ACN002_3729 FORC28_0142 HMPREF3040_00659A0A066TAW79
50S ribosomal protein L4rplD PA4262Q9HWD69
Acetyl-CoA acetyltransferase (EC (Acetoacetyl-CoA thiolase)atoB PA2001Q9I2A89
Acid stress chaperone HdeBhdeB EcSMS35_3811B1LJ519
Aromatic-amino-acid aminotransferase (EC PA0870P433369
ATP synthase gamma chain (ATP synthase F1 sector gamma subunit) (F-ATPase gamma subunit)atpG AML07_02030 APZ14_19945 AUS26_01160 ERS150876_04310A0A0F3V6849
ATP synthase subunit b (ATP synthase F(0) sector subunit b) (ATPase subunit I) (F-type ATPase subunit b) (F-ATPase subunit b)atpF PA5558Q9HT169
ATP-dependent Clp protease proteolytic subunit (EC (Endopeptidase Clp)clpP BX52_22040A0A0E2TM389
ATP-independent periplasmic protein-refolding chaperone (Periplasmic protein) (Spheroplast protein Y)spy A4T40_13405 AC067_18045 AWP75_00905 BK334_13905 BK373_05185 BMT49_11300 BMT97_01185 ECONIH1_10065 MJ49_22630 MS6198_19680A0A0A1A8M79
Bacterioferritin (BFR) (EC bfrA PA4235Q9HWF99
Branched-chain-amino-acid aminotransferase (BCAT) (EC PA5013O864289
Cbb3-type cytochrome c oxidase subunitccoP1 PA1552Q9I3G59
Conserved cytoplasmic membrane protein, CmpX proteincmpX PA1775G3XCV69
Cytochrome c4cc4 PA5490P001069
Cytosol aminopeptidase (EC (Leucine aminopeptidase) (LAP) (EC (Leucyl aminopeptidase)pepA phpA PA3831O688229
D-amino acid dehydrogenase 1 (EC 1.4.99.-) (D-alanine dehydrogenase 1)dadA1 dadA PA5304Q9HTQ09
D-lactate dehydrogenase (EC SY51_12285A0A061L5F79
Dihydrolipoyl dehydrogenase (EC (Dihydrolipoamide dehydrogenase) (E3 component of 2-oxoglutarate dehydrogenase complex) (Glycine oxidation system L-factor) (LPD-GLC)lpdG PA1587Q9I3D19
DNA-binding protein HU-betahupB PA1804P053849
Fructose-bisphosphate aldolase (EC SY51_12090A0A066T4679
Glucarate dehydratase (EC BE932_11880 SY51_15630A0A061L8K29
Glutamate dehydrogenasegdhA A5958_22475 A9R57_26735 AA102_21515 ACN81_10430 AKG99_11255 AM270_03110 AMK83_18170 AWP75_00995 BE957_14575 BHF46_17405 BHS87_09965 BK251_14135 BK292_17970 BK400_10530 BMT53_01185 ERS085365_03014 ERS085366_03687 ERS085374_01255 ERS085379_02202 ERS085386_01277 ERS085416_03436 ERS139211_02921 ERS139235_00788 ERS150873_00785 GJ11_12210 GJ12_11390 HW42_13030 JD73_23555 PU06_10730 UN86_21855 WQ89_08770 WR15_13615A0A037Y7V49
Glutamine--tRNA ligase (EC (Glutaminyl-tRNA synthetase) (GlnRS)glnS E2348C_0571B7UKW19
Glyoxylate/hydroxypyruvate reductase B (EC (EC BE932_16875 SY51_20310A0A061YF539
Homogentisate 1,2-dioxygenase (HGDO) (EC (Homogentisate oxygenase) (Homogentisic acid oxidase) (Homogentisicase)hmgA PA2009Q9X4G09
Hypoxanthine phosphoribosyltransferase (EC
Ketol-acid reductoisomerase (NADP(+)) (KARI) (EC (Acetohydroxy-acid isomeroreductase) (AHIR) (Alpha-keto-beta-hydroxylacyl reductoisomerase) (Ketol-acid reductoisomerase type 1) (Ketol-acid reductoisomerase type I)ilvC PA4694Q9HVA29
KHG/KDPG aldolase (Keto-deoxy-phosphogluconate aldolase) (EC (EC SY51_10260A0A061KZJ19
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)bkdB PA2249Q9I1M09
Lipotoxon F, LptFlptF PA3692Q9HXU89
Membrane-bound lysozyme inhibitor of C-type lysozymemliC PA0867Q9I5749
Multidrug resistance protein MexB (Multidrug-efflux transporter MexB)mexB PA0426P520029
O-acetylserine synthasecysE PA3816Q9HXI69
Peptidyl-prolyl cis-trans isomerase (EC
Peptidylprolyl isomerase (EC PA1805Q9I2T89
Phosphoglucosamine mutase (EC Ec53638_2708A0A0E1SXX69
Phosphoheptose isomerase (EC (Sedoheptulose 7-phosphate isomerase)gmhA EcE24377A_0254A7ZHY19
Polyribonucleotide nucleotidyltransferase (EC (Polynucleotide phosphorylase) (PNPase)pnp PA4740Q9HV599
Probable bacteriophage proteinPA0620G3XD719
Probable carboxyl-terminal proteasePA5134Q9HU509
Probable outer membrane receptor for iron transportPA4514G3XCY89
Probable TonB-dependent receptorPA3268Q9HYX39
Protein PilJpilJ PA0411P422579
Protein RecA (Recombinase A)recA PA3617P082809
Protein TolQtolQ PA0969P505989
Protein translocase subunit SecAsecA PA4403Q9LCT39
Putative lipoproteinqseG BE932_10560 ERS085406_03494 SY51_14630A0A061YI789
Ribonuclease E (RNase E) (EC PA2976Q9HZM89
Ribosome-binding factor ArbfA EcE24377A_3651A7ZS649
S-adenosylmethionine synthase (AdoMet synthase) (EC (MAT) (Methionine adenosyltransferase)metK PA0546Q9I5Z09
Stringent starvation protein AsspA Z4587 ECs4102P0ACA59
Succinate dehydrogenase (B subunit)sdhB PA1584Q9I3D49
Succinate--CoA ligase [ADP-forming] subunit alpha (EC (Succinyl-CoA synthetase subunit alpha) (SCS-alpha)sucD PA1589Q515679
Superoxide dismutase (EC SY51_09240A0A066T0H79
Superoxide dismutase [Cu-Zn] (EC SY51_09190A0A066SS329
Threonine--tRNA ligase (EC (Threonyl-tRNA synthetase) (ThrRS)thrS A9R57_03290 AC789_1c19000 BE932_04045 BHF46_17190 BHS87_09745 BJJ90_13785 BK400_10740 BMT49_11175 BMT97_11215 ERS085365_00839 ERS085416_00776 ERS139211_01169 ERS150873_00743 RG28_13495 SY51_09570 WQ89_08555 WR15_13830A0A037Y4309
Thymidine phosphorylase (EC (TdRPase)deoA BE932_22905 SY51_25225A0A066SPP09
Transcriptional regulator SlyAslyA E2348C_1729P0A4U59
Triosephosphate isomerase (TIM) (TPI) (EC (Triose-phosphate isomerase)tpiA EcE24377A_4453A7ZUD39
tRNA pseudouridine synthase B (EC (tRNA pseudouridine(55) synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase)truB UN91_15490A0A0F3UEF89
Uncharacterized proteinPA5178Q9HU119
Uncharacterized proteinPA4972Q9HUJ39
Uncharacterized proteinPA0946Q9I5129
Uncharacterized proteinPA0020Q9I7A79
Uncharacterized proteinBE932_14070 SY51_17615A0A066T1S59
Zinc-binding dehydrogenaseBE932_25310 SY51_01810A0A066T5E19
2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (EC (Glycine acetyltransferase)kbl BE932_17280 SY51_20645A0A061KEJ78
30S ribosomal protein S2rpsB PA3656O828508
30S ribosomal protein S3rpsC PA4257Q9HWE18
30S ribosomal protein S3rpsC CKO_04729A8AQL08
30S ribosomal protein S4rpsD PA4239O527598
30S ribosomal protein S5rpsE PA4246Q9HWF28
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase (EC (5-keto-4-deoxyuronate isomerase) (DKI isomerase)kduI A4T40_19465 BE963_04000 BK334_11580 ECONIH1_16245 MS6198_31660A0A0A1A8L68
50S ribosomal protein L1rplA PA4273Q9HWC68
50S ribosomal protein L11rplK PA4274Q9HWC58
50S ribosomal protein L13rplM EcE24377A_3714A7ZSC58
50S ribosomal protein L2rplB PA4260Q9HWD88
50S ribosomal protein L20rplT CKO_01742A8AHA88
50S ribosomal protein L22rplV CKO_04730A8AQL28
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