EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
Myb/SANT-like DNA-binding domain-containing protein 4Msantd4Q91YU34
Myocardin (Basic SAP coiled-coil transcription activator 2) (SRF cofactor protein)Myocd Bsac2 Mycd SrfcpQ8VIM54
Myosin light chain 1/3, skeletal muscle isoform (MLC1/MLC3) (MLC1F/MLC3F) (Myosin light chain alkali 1/2) (Myosin light chain A1/A2)Myl1 MylfP059774
Myosin-binding protein C, cardiac-typeMybpc3Q3UIK04
N-acetyl-D-glucosamine kinase (N-acetylglucosamine kinase) (EC (GlcNAc kinase)Nagk GnkQ9QZ084
N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1)Esco1 Kiaa1911Q69Z694
N-alpha-acetyltransferase 25, NatB auxiliary subunit (Mitochondrial distribution and morphology protein 20) (N-terminal acetyltransferase B complex subunit MDM20) (NatB complex subunit MDM20) (N-terminal acetyltransferase B complex subunit NAA25)Naa25 Mdm20Q8BWZ34
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (Complex I-MWFE) (CI-MWFE) (NADH-ubiquinone oxidoreductase MWFE subunit)Ndufa1O356834
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (Complex I-42kD) (CI-42kD) (NADH-ubiquinone oxidoreductase 42 kDa subunit)Ndufa10Q99LC34
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (Complex I-B14) (CI-B14) (NADH-ubiquinone oxidoreductase B14 subunit)Ndufa6Q9CQZ54
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (Complex I-AGGG) (CI-AGGG) (NADH-ubiquinone oxidoreductase AGGG subunit)Ndufb2Q9CPU24
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (EC (EC (Complex I-51kD) (CI-51kD) (NADH-ubiquinone oxidoreductase 51 kDa subunit)Ndufv1Q91YT04
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 (Complex I-15 kDa) (CI-15 kDa) (NADH-ubiquinone oxidoreductase 15 kDa subunit) [Cleaved into: NADH dehydrogenase [ubiquinone] iron-sulfur protein 5, N-terminally processed]Ndufs5Q99LY94
NEDD4 family-interacting protein 2Ndfip2M0QWK14
NEDD4-binding protein 1 (N4BP1)N4bp1 Kiaa0615Q6A0374
NEDD8-activating enzyme E1 regulatory subunit (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1) (Amyloid protein-binding protein 1)Nae1 Appbp1Q8VBW64
Netrin-G2 (Laminet-2)Ntng2 Lmnt2Q8R4F14
Neuron navigator 3Nav3E9QMF54
Neuronal PAS domain-containing protein 3Npas3F8VQB24
Neuronal regeneration-related protein (Neuronal protein 3.1) (Protein p311)Nrep D0H4S114 P311Q074754
Neuronal-specific septin-3Sept3 Sep3Q9Z1S54
Neuropilin-1 (A5 protein) (CD antigen CD304)Nrp1 NrpP973334
Neutral alpha-glucosidase AB (EC (Alpha-glucosidase 2) (Glucosidase II subunit alpha)Ganab G2an Kiaa0088Q8BHN34
Neutral cholesterol ester hydrolase 1 (NCEH) (EC 3.1.1.-) (Arylacetamide deacetylase-like 1) (Chlorpyrifos oxon-binding protein) (CPO-BP)Nceh1 Aadacl1 Kiaa1363Q8BLF14
Neutrophil cytosol factor 1 (NCF-1) (47 kDa neutrophil oxidase factor) (NCF-47K) (Neutrophil NADPH oxidase factor 1) (p47-phox)Ncf1Q090144
Nischarin (Imidazoline receptor 1) (I-1) (IR1) (Imidazoline receptor I-1-like protein) (Imidazoline-1 receptor) (I1R)Nisch Kiaa0975Q80TM94
Nitric oxide-associated protein 1Noa1 MNCb-4931Q9JJG94
Noelin-3 (Olfactomedin-3) (Optimedin)Olfm3 Noe3P630564
Non-metastatic cells 7, protein expressed in, isoform CRA_cNme7 mCG_123882Q3UMG64
Novel protein (Protein Gm11487)Gm11487 OTTMUSG00000001246 RP23-289L21.1-001Q5RIS04
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (CBP20)Ncbp2 Cbp20Q9CQ494
Nuclear envelope pore membrane protein POM 121 (Nucleoporin Nup121) (Pore membrane protein of 121 kDa)Pom121 Nup121Q8K3Z94
Nuclear export mediator factor Nemf (Serologically defined colon cancer antigen 1 homolog)Nemf Sdccag1Q8CCP04
Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein)NfixP702574
Nuclear nucleic acid-binding protein C1D (mC1D) (Small unique nuclear receptor corepressor) (Sun-CoR) (SunCoR)C1d SuncorO354734
Nuclear pore membrane glycoprotein 210 (Nuclear pore protein gp210) (Nuclear envelope pore membrane protein POM 210) (POM210) (Nucleoporin Nup210) (Pore membrane protein of 210 kDa)Nup210 Kiaa0906Q9QY814
Nuclear RNA export factor 1 (Tip-associated protein) (Tip-associating protein) (mRNA export factor TAP)Nxf1 TapQ99JX74
Nucleolar complex protein 2 homologNoc2lJ3QK524
Nucleolin (Protein C23)Ncl NucP094054
Opioid growth factor receptor-like protein 1Ogfrl1Q8VE524
Origin recognition complex subunit 4Orc4 Orc4lO887084
Oxidative stress induced growth inhibitor 1 (Protein Osgin1) (RIKEN cDNA 1700012B18, isoform CRA_b)Osgin1 1700012B18Rik mCG_19046Q8VC104
Pachytene checkpoint protein 2 homolog (Thyroid hormone receptor interactor 13) (Thyroid receptor-interacting protein 13) (TR-interacting protein 13) (TRIP-13)Trip13 Pch2Q3UA064
Paired-Ig-like receptor A11Pira11 OTTMUSG00000017169Q3ZB544
Palmitoyltransferase ZDHHC3 (EC (GABA-A receptor-associated membrane protein 1) (Golgi-specific DHHC zinc finger protein) (Zinc finger DHHC domain-containing protein 3) (DHHC-3)Zdhhc3 Godz Gramp1Q8R1734
Paraplegin (EC 3.4.24.-)Spg7Q3ULF44
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP)Pard3 Par3Q99NH24
PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein)Pdlim5 EnhQ8CI514
PDZ domain-containing protein 11Pdzd11 Pdzk11Q9CZG94
Peptidyl-prolyl cis-trans isomerase F, mitochondrial (PPIase F) (EC (Cyclophilin D) (CyP-D) (CypD) (Cyclophilin F) (Rotamase F)PpifQ99KR74
Peptidyl-prolyl cis-trans isomerase FKBP1A (PPIase FKBP1A) (EC (12 kDa FK506-binding protein) (12 kDa FKBP) (FKBP-12) (Calstabin-1) (FK506-binding protein 1A) (FKBP-1A) (Immunophilin FKBP12) (Rotamase)Fkbp1a Fkbp1P268834
Peptidyl-prolyl cis-trans isomerase-like 3 (PPIase) (EC (CYP10L) (Cyclophilin-like protein PPIL3) (Rotamase PPIL3)Ppil3 Cyp10lQ9D6L84
Perforin-1 (P1) (Cytolysin) (Lymphocyte pore-forming protein)Prf1 PfpP108204
Perilipin-3 (Cargo selection protein TIP47) (Mannose-6-phosphate receptor-binding protein 1)Plin3 M6prbp1 Tip47Q9DBG54
Perilipin-4 (Adipocyte protein S3-12)Plin4 Kiaa1881O884924
Peroxisome biogenesis factor 2 (Peroxin-2) (Peroxisomal membrane protein 3) (Peroxisome assembly factor 1) (PAF-1)Pex2 Paf1 Pmp35 Pxmp3P550984
PEST proteolytic signal-containing nuclear protein (PCNP) (PEST-containing nuclear protein)PcnpQ6P8I44
PHD finger protein 3 (Protein Phf3)Phf3B2RQG24
Phosphatase and actin regulator 4 (Protein Humpty dumpty) (Humdy)Phactr4 Kiaa4120Q501J74
Phosphatidate phosphatase LPIN1 (EC (Fatty liver dystrophy protein) (Lipin-1)Lpin1 FldQ91ZP34
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC (EC (EC (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)Pten Mmac1O085864
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC (Phosphatidylinositol 5-phosphate 4-kinase type II gamma) (PI(5)P 4-kinase type II gamma) (PIP4KII-gamma)Pip4k2c Pip5k2cQ91XU34
Phosphoglycerate mutase 1 (EC (EC (EC (BPG-dependent PGAM 1) (Phosphoglycerate mutase isozyme B) (PGAM-B)Pgam1Q9DBJ14
Phospholipase D3 (PLD 3) (EC (Choline phosphatase 3) (Phosphatidylcholine-hydrolyzing phospholipase D3) (Schwannoma-associated protein 9) (SAM-9)Pld3 Sam9O354054
Platelet-activating factor acetylhydrolase 2, cytoplasmic (EC (Serine-dependent phospholipase A2) (SD-PLA2)Pafah2Q8VDG74
Pleckstrin homology domain-containing family F member 2 (PH domain-containing family F member 2)Plekhf2Q91WB44
Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Synectin-binding RhoA exchange factor) (SYX)Plekhg5 Kiaa0720 SyxQ66T024
Pleckstrin homology domain-containing family M member 1 (PH domain-containing family M member 1)Plekhm1Q7TSI14
Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha)Phldb1 Kiaa0638 Ll5aQ6PDH04
Plexin-A2 (Plex 2) (Plexin-2)Plxna2 Kiaa0463P702074
Poliovirus receptor (Poliovirus receptor-related protein 2) (Tage4 receptor)Pvr D7Ertd458e Tage4 mCG_4885Q8K0944
Polycomb protein Suz12 (Suppressor of zeste 12 protein homolog)Suz12 D11Ertd530e Kiaa0160Q80U704
Polymerase delta-interacting protein 2Poldip2Q91VA64
Pre-B-cell leukemia transcription factor 1 (Homeobox protein PBX1)Pbx1 Pbx-1P417784
Pre-miRNA 5'-monophosphate methyltransferase (EC 2.1.1.-) (BCDIN3 domain-containing protein)Bcdin3dQ91YP14
Pre-mRNA-splicing factor SLU7Slu7 D11Ertd730eQ8BHJ94
Predicted gene, OTTMUSG00000017677 (Protein DXBay18) (Protein Gm14685)OTTMUSG00000017677 DXBay18 Gm14685Q52KH64
Prefoldin 1 (Prefoldin subunit 1)Pfdn1 mCG_121970Q9CQF74
Prickle-like protein 3Prickle3 Lmo6Q8BNH24
Probable ATP-dependent RNA helicase DDX6 (EC (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK homolog)Ddx6 Hlr2 RckP548234
Probable C-mannosyltransferase DPY19L3 (EC 2.4.1.-) (Dpy-19-like protein 3) (Protein dpy-19 homolog 3)Dpy19l3Q71B074
Probable E3 ubiquitin-protein ligase DTX2 (EC 6.3.2.-) (Protein deltex-2) (Deltex2) (mDTX2)Dtx2Q8R3P24
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (EC (Lysyl hydroxylase 2) (LH2)Plod2Q9R0B94
Programmed cell death protein 7Pdcd7Q3U2X64
Proliferation-associated protein 2G4 (IRES-specific cellular trans-acting factor 45 kDa) (ITAF45) (Mpp1) (Proliferation-associated protein 1) (Protein p38-2G4)Pa2g4 Ebp1 PlfapP505804
Proline and serine-rich protein 1Proser1Q5PRE54
Proline-rich AKT1 substrate 1 (Proline-rich AKT substrate)Akt1s1 PrasQ9D1F44
Proline-rich protein 2Prp2F8VPU94
Proteasome activator complex subunit 4 (Proteasome activator PA200) (Protein TEMO)Psme4 Kiaa0077Q5SSW24
Proteasome subunit beta type-8 (EC (Low molecular mass protein 7) (Macropain subunit C13) (Multicatalytic endopeptidase complex subunit C13) (Proteasome component C13) (Proteasome subunit beta-5i)Psmb8 Lmp7 Mc13P280634
Protein 1700019G17Rik1700019G17RikE0CYM04
Protein AglAglF8VPN44
Protein Ankhd1Ankhd1E9PUR04
Protein Ankrd11Ankrd11E9Q4F74
Protein archease (Protein ZBTB8OS)Zbtb8os ArchQ505B74
Protein arginine N-methyltransferase 7 (EC 2.1.1.-) (Histone-arginine N-methyltransferase PRMT7) (EC ([Myelin basic protein]-arginine N-methyltransferase PRMT7) (EC Kiaa1933Q922X94
Protein argonaute-2 (Argonaute2) (mAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Piwi/argonaute family protein meIF2C2) (Protein slicer)Ago2 Eif2c2 Kiaa4215Q8CJG04
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