EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
Alpha-1-acid glycoprotein 1 (AGP 1) (Orosomucoid-1) (OMD 1)Orm1 Agp1 Orm-1Q605903
Alpha-1-antitrypsin 1-3 (Alpha-1 protease inhibitor 3) (Alpha-1 protease inhibitor 6) (Alpha-1-antitrypsin 1-6) (Serine protease inhibitor 1-3) (Serine protease inhibitor 1-6) (Serine protease inhibitor A1c) (Serpin A1c)Serpina1c Dom3 Dom6 Spi1-3 Spi1-6Q008963
Alpha-2-antiplasmin (Alpha-2-AP) (Alpha-2-plasmin inhibitor) (Alpha-2-PI) (Serpin F2)Serpinf2 PliQ612473
Alpha-2-HS-glycoprotein (Countertrypin) (Fetuin-A)Ahsg FetuaP296993
Alpha-actinin-3 (Alpha-actinin skeletal muscle isoform 3) (F-actin cross-linking protein)Actn3O889903
Alpha-defensin 21 (Defensin-related cryptdin-21)Defa21 Defcr21Q8C1P23
Alpha-enolase (EC (2-phospho-D-glycerate hydro-lyase) (Enolase 1) (Non-neural enolase) (NNE)Eno1 Eno-1P171823
Alpha-interferon (MCG6571) (Predicted gene, OTTMUSG00000007655) (Protein Gm12597)Gm12597 MuIFN-alpha-A OTTMUSG00000007655 mCG_6571Q617183
Alpha-methylacyl-CoA racemase (EC (2-methylacyl-CoA racemase)Amacr Macr1O091743
Alpha/beta hydrolase domain-containing protein 17B (EC 3.-.-.-)Abhd17bQ7M7593
Amphoterin-induced protein 1 (AMIGO-1) (Alivin-2)Amigo1 Ali2 Amigo Kiaa1163Q80ZD83
Amyloid beta A4 precursor protein-binding family B member 2Apbb2Q9DBR43
Amyloid protein-binding protein 2 (Amyloid beta precursor protein-binding protein 2) (APP-BP2)Appbp2 Kiaa0228Q9DAX93
Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10)Anapc10 Apc10Q8K2H63
Angiopoietin-related protein 2 (Angiopoietin-like protein 2)Angptl2 Arp2Q9R0453
Anion exchange protein 3 (AE 3) (Anion exchanger 3) (Neuronal band 3-like protein) (Solute carrier family 4 member 3)Slc4a3 Ae3P162833
Ankyrin repeat and BTB/POZ domain-containing protein BTBD11 (BTB/POZ domain-containing protein 11)Btbd11Q6GQW03
Ankyrin repeat and MYND domain-containing protein 2Ankmy2Q3TPE93
Ankyrin repeat and SOCS box protein 12 (ASB-12)Asb12Q9D7383
Ankyrin repeat and SOCS box protein 13 (ASB-13)Asb13Q8VBX03
Ankyrin repeat and SOCS box protein 7 (ASB-7)Asb7Q91ZU03
Ankyrin repeat and zinc finger domain-containing protein 1Ankzf1 D1Ertd161eQ80UU13
Ankyrin repeat domain-containing protein 34CAnkrd34cQ8BLB83
Ankyrin repeat family A protein 2 (RFXANK-like protein 2)Ankra2 AnkraQ99PE23
Annexin A7 (Annexin VII) (Annexin-7) (Synexin)Anxa7 Anx7Q070763
Antileukoproteinase (ALP) (Secretory leukocyte protease inhibitor)SlpiP974303
AP-1 complex subunit mu-1 (AP-mu chain family member mu1A) (Adapter-related protein complex 1 subunit mu-1) (Adaptor protein complex AP-1 subunit mu-1) (Clathrin assembly protein complex 1 mu-1 medium chain 1) (Clathrin coat assembly protein AP47) (Clathrin coat-associated protein AP47) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Mu-adaptin 1) (Mu1A-adaptin)Ap1m1 CltnmP355853
AP-2 complex subunit alpha-2 (100 kDa coated vesicle protein C) (Adapter-related protein complex 2 subunit alpha-2) (Adaptor protein complex AP-2 subunit alpha-2) (Alpha-adaptin C) (Alpha2-adaptin) (Clathrin assembly protein complex 2 alpha-C large chain) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit)Ap2a2 AdtabP174273
AP-2 complex subunit mu (AP-2 mu chain) (Adapter-related protein complex 2 subunit mu) (Adaptor protein complex AP-2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein)Ap2m1 Clapm1P840913
AP2-associated protein kinase 1 (EC (Adaptor-associated kinase 1)Aak1 Kiaa1048Q3UHJ03
Apoptosis regulatory protein Siva (CD27-binding protein) (CD27BP)Siva1 SivaO549263
Apoptosis-inducing factor 2 (EC 1.-.-.-) (Apoptosis-inducing factor homologous mitochondrion-associated inducer of death) (Apoptosis-inducing factor-like mitochondrion-associated inducer of death)Aifm2 AmidQ8BUE43
Arachidonate 15-lipoxygenase (15-LOX) (EC (12/15-lipoxygenase) (12/15-LO) (Arachidonate 12-lipoxygenase, leukocyte-type) (12-LOX) (L-12LO) (EC (Arachidonate omega-6 lipoxygenase)Alox15 Alox12lP396543
Archaemetzincin-2 (EC 3.4.-.-) (Archeobacterial metalloproteinase-like protein 2)Amz2Q400C83
Arf-GAP with dual PH domain-containing protein 2 (Centaurin-alpha-2) (Cnt-a2)Adap2 Centa2Q8R2V53
Arginine vasopressin-induced protein 1 (AVP-induced protein 1) (Arginine vasopressin-induced transcript 32 protein) (VIP32) (VIT32)Avpi1Q9D7H43
Armadillo repeat-containing protein 10Armc10Q9D0L73
Arrestin domain-containing protein 1Arrdc1Q99KN13
Asparagine synthetase [glutamine-hydrolyzing] (EC (Glutamine-dependent asparagine synthetase)AsnsQ610243
Asparagine-linked glycosylation 12 homolog (Yeast, alpha-1,6-mannosyltransferase) (Asparagine-linked glycosylation 12 homolog (Yeast, alpha-1,6-mannosyltransferase), isoform CRA_c) (Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase)Alg12 mCG_7282Q8VCA23
AT-rich interactive domain-containing protein 5B (ARID domain-containing protein 5B) (Developmentally and sexually retarded with transient immune abnormalities protein) (Desrt) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2)Arid5b Desrt Mrf2Q8BM753
Atlastin-2 (EC 3.6.5.-) (ADP-ribosylation factor-like protein 6-interacting protein 2) (ARL-6-interacting protein 2) (Aip-2)Atl2 Arl6ip2Q6PA063
ATP synthase subunit e, mitochondrial (ATPase subunit e)Atp5i Atp5k Lfm-1 Lfm1Q061853
ATP synthase subunit gamma, mitochondrial (F-ATPase gamma subunit)Atp5c1Q91VR23
ATP-binding cassette sub-family A member 7Abca7Q91V243
ATP-binding cassette sub-family G member 5 (Sterolin-1)Abcg5Q99PE83
ATP-dependent DNA helicase Q1 (EC (DNA-dependent ATPase Q1) (RecQ protein-like 1)Recql Recql1Q9Z1293
ATP-dependent RNA helicase DDX3X (EC (D1Pas1-related sequence 2) (DEAD box RNA helicase DEAD3) (mDEAD3) (DEAD box protein 3, X-chromosomal) (Embryonic RNA helicase)Ddx3x D1Pas1-rs2 Ddx3 Dead3 ErhQ621673
ATP-sensitive inward rectifier potassium channel 1 (ATP-regulated potassium channel ROM-K) (Inward rectifier K(+) channel Kir1.1) (Potassium channel, inwardly rectifying subfamily J member 1)Kcnj1O883353
Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog)AireQ9Z0E33
B-cell CLL/lymphoma 6 member B protein (Bcl6-associated zinc finger protein)Bcl6b BazfO882823
B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein)Bcl7cO086643
B-cell receptor-associated protein 31 (BCR-associated protein 31) (Bap31) (p28)Bcap31 Bap31Q613353
Baculoviral IAP repeat-containing protein 2 (EC 6.3.2.-) (Inhibitor of apoptosis protein 2) (IAP-2) (mIAP-2) (mIAP2)Birc2 Birc3 Iap2Q622103
Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N)Epb41l1 Epb4 Epb4.1l1 Kiaa0338Q9Z2H53
Bardet-Biedl syndrome 2 protein homologBbs2Q9CWF63
Barrier-to-autointegration factor (Breakpoint cluster region protein 1) (LAP2-binding protein 1) [Cleaved into: Barrier-to-autointegration factor, N-terminally processed]Banf1 Baf Bcrp1 L2bp1O549623
Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) [Cleaved into: Endorepellin; LG3 peptide]Hspg2Q057933
Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis)Bbc3 PumaQ99ML13
Bcl-2-modifying factorBmfQ91ZE93
BCL-6 corepressor (BCoR)Bcor Kiaa1575Q8CGN43
Beta-crystallin B2 (Beta-B2 crystallin) (Beta-crystallin Bp)Crybb2P626963
Beta-defensin 2 (BD-2) (mBD-2) (Defensin, beta 2)Defb2P820203
Beta-defensin 3 (BD-3) (mBD-3) (Defensin, beta 3)Defb3 Bd3Q9WTL03
Beta-hexosaminidase subunit beta (EC (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (N-acetyl-beta-glucosaminidase subunit beta)HexbP200603
Beta-sarcoglycan (Beta-SG) (43 kDa dystrophin-associated glycoprotein) (43DAG)SgcbP823493
Beta-soluble NSF attachment protein (SNAP-beta) (Brain protein I47) (N-ethylmaleimide-sensitive factor attachment protein beta)Napb SnapbP286633
Beta/gamma crystallin domain-containing protein 3Crybg3Q80W493
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPS synthase 2) (PAPSS 2) (Sulfurylase kinase 2) (SK 2) (SK2) [Includes: Sulfate adenylyltransferase (EC (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)]Papss2 Atpsk2O884283
Bifunctional coenzyme A synthase (CoA synthase) [Includes: Phosphopantetheine adenylyltransferase (EC (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase) (PPAT); Dephospho-CoA kinase (DPCK) (EC (Dephosphocoenzyme A kinase) (DPCOAK)]Coasy Ukr1Q9DBL73
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST-4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 4 (EC 2.8.2.-)]Ndst4 Hsst4Q9EQW83
Bile salt-activated lipase (BAL) (EC (EC (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase)Cel Lip1Q642853
Biotinidase (Biotinase) (EC
Bone morphogenetic protein 1 (BMP-1) (EC (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP)Bmp1P980633
Bone morphogenetic protein 2 (BMP-2) (Bone morphogenetic protein 2A) (BMP-2A)Bmp2 Bmp-2P212743
Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC (Activin receptor-like kinase 3) (ALK-3) (BMP-2/BMP-4 receptor) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)Bmpr1a Acvrlk3 BmprP368953
Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC (Activin receptor-like kinase 6) (ALK-6) (Serine/threonine-protein kinase receptor R6) (SKR6) (CD antigen CDw293)Bmpr1b Acvrlk6P368983
BPI fold-containing family A member 1 (Palate lung and nasal epithelium clone protein)Bpifa1 PluncP973613
BPI fold-containing family A member 2 (Parotid secretory protein) (PSP)Bpifa2 PspP077433
Brain acid soluble protein 1 (22 kDa neuronal tissue-enriched acidic protein) (Neuronal axonal membrane protein NAP-22)Basp1 Nap22Q91XV33
Branched-chain-amino-acid aminotransferase, mitochondrial (BCAT(m)) (EC Bcatm Eca40O358553
BSD domain-containing protein 1Bsdc1Q80Y553
BTB/POZ domain-containing protein 1 (Glucose signal-repressing protein)Btbd1 GsrpP585443
BTB/POZ domain-containing protein 16Btbd16E9Q1733
BTB/POZ domain-containing protein KCTD11Kctd11 RenQ8K4853
BTB/POZ domain-containing protein KCTD6Kctd6Q8BNL53
C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (MIP-1 alpha receptor) (CD antigen CD195)Ccr5 Cmkbr5P516823
C-Jun-amino-terminal kinase-interacting protein 1 (JIP-1) (JNK-interacting protein 1) (Islet-brain-1) (IB-1) (JNK MAP kinase scaffold protein 1) (Mitogen-activated protein kinase 8-interacting protein 1)Mapk8ip1 Ib1 Jip1 Mapk8ip Prkm8ipQ9WVI93
C-terminal-binding protein 2 (CtBP2)Ctbp2P565463
C-X-C motif chemokine 11 (Interferon-inducible T-cell alpha chemoattractant) (I-TAC) (Small-inducible cytokine B11)Cxcl11 Scyb11Q9JHH53
Ca(2+)-independent N-acyltransferase (iNAT) (EC 2.3.1.-) (H-rev107-like protein 5) (HRAS-like suppressor 5) (HRSL5)Hrasls5 Hrlp5Q9CPX53
Cadherin-11 (OSF-4) (Osteoblast cadherin) (OB-cadherin)Cdh11 Cad-11P552883
Calcineurin-like phosphoesterase domain-containing protein 1 (EC 3.1.-.-)Cpped1 Cstp1Q8BFS63
Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) (Calcitonin receptor-like receptor)Calcrl CrlrQ9R1W53
Calcium and integrin-binding protein 1 (CIB) (Calmyrin) (DNA-PKcs-interacting protein) (Kinase-interacting protein) (KIP)Cib1 Cib Kip PrkdcipQ9Z0F43
Calcium uptake protein 2, mitochondrial (EF-hand domain-containing family member A1)Micu2 Efha1Q8CD103
Calcium-activated potassium channel subunit beta-1 (BK channel subunit beta-1) (BKbeta) (BKbeta1) (Calcium-activated potassium channel, subfamily M subunit beta-1) (Calcium-activated potassium channel subunit beta) (Charybdotoxin receptor subunit beta-1) (K(VCA)beta-1) (Maxi K channel subunit beta-1) (Slo-beta-1) (Slo-beta)Kcnmb1Q8CAE33
Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25)Slc25a25 Kiaa1896 Scamc2A2ASZ83
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