EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
DnaJ homolog subfamily B member 4Dnajb4Q9D8323
DnaJ homolog subfamily B member 5 (Heat shock protein Hsp40-3) (Heat shock protein cognate 40) (Hsc40)Dnajb5 Hsc40O891143
DnaJ homolog subfamily B member 9 (Endoplasmic reticulum DNA J domain-containing protein 4) (ER-resident protein ERdj4) (ERdj4) (mDj7)Dnajb9Q9QYI63
DnaJ homolog subfamily C member 17Dnajc17Q91WT43
DnaJ homolog subfamily C member 5 (Cysteine string protein) (CSP)Dnajc5 CspP609043
DnaJ homolog subfamily C member 5B (Cysteine string protein beta) (CSP-beta)Dnajc5bQ9CQ943
Docking protein 5 (Downstream of tyrosine kinase 5)Dok5Q91ZM93
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4Ost4Q99LX83
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (Oligosaccharyl transferase subunit STT3B) (STT3-B) (EC 2.4.99.18) (B6dom1 antigen) (Source of immunodominant MHC-associated peptides)Stt3b SimpQ3TDQ13
Double-strand break repair protein MRE11A (MmMRE11A) (Meiotic recombination 11 homolog 1) (MRE11 homolog 1) (Meiotic recombination 11 homolog A) (MRE11 homolog A)Mre11a Mre11Q612163
Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (RNA adenosine deaminase 1)AdarQ99MU33
Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Clk4O354933
Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (Large GTP-binding protein) (LargeG) (Optic atrophy protein 1 homolog) [Cleaved into: Dynamin-like 120 kDa protein, form S1]Opa1P582813
Dynein heavy chain 2, axonemalDnah2 Dnahc2D3Z6673
Dynein intermediate chain 1, axonemal (Axonemal dynein intermediate chain 1)Dnai1 Dnaic1Q8C0M83
Dynein light chain 2, cytoplasmic (8 kDa dynein light chain b) (DLC8) (DLC8b) (Dynein light chain LC8-type 2)Dynll2 Dlc2Q9D0M53
Dysbindin (Biogenesis of lysosome-related organelles complex 1 subunit 8) (BLOC-1 subunit 8) (Dysbindin-1) (Dystrobrevin-binding protein 1) (Hermansky-Pudlak syndrome 7 protein homolog) (HPS7 protein homolog)Dtnbp1 Bloc1s8 SdyQ91WZ83
Dysbindin domain-containing protein 2Dbndd2 D2Bwg0891eQ9CRD43
Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (Protein DMR-N9)Dmwd Dm9Q082743
E1A-binding protein p400 (EC 3.6.4.-) (Domino homolog) (mDomino) (p400 kDa SWI2/SNF2-related protein)Ep400 Kiaa1498Q8CHI83
E3 SUMO-protein ligase CBX4 (EC 6.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (mPc2)Cbx4 Pc2O551873
E3 ubiquitin-protein ligase MARCH2 (EC 6.3.2.-) (Membrane-associated RING finger protein 2) (Membrane-associated RING-CH protein II) (MARCH-II)41335Q99M023
E3 ubiquitin-protein ligase MARCH3 (EC 6.3.2.-) (Membrane-associated RING finger protein 3) (Membrane-associated RING-CH protein III) (MARCH-III)41336Q8BRX93
E3 ubiquitin-protein ligase MARCH6 (EC 6.3.2.-) (Membrane-associated RING finger protein 6) (Membrane-associated RING-CH protein VI) (MARCH-VI)March6 Kiaa0597Q6ZQ893
E3 ubiquitin-protein ligase Midline-1 (EC 6.3.2.-) (Midin) (RING finger protein Midline-1) (Tripartite motif-containing protein 18)Mid1 Fxy Trim18O705833
E3 ubiquitin-protein ligase RBBP6 (EC 6.3.2.-) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding protein 6) (p53-associated cellular protein of testis)Rbbp6 P2pr PactP978683
E3 ubiquitin-protein ligase RFWD2 (EC 6.3.2.-) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1) (RING finger and WD repeat domain protein 2)Rfwd2 Cop1Q9R1A83
E3 ubiquitin-protein ligase RNF126 (EC 6.3.2.-) (RING finger protein 126)Rnf126Q91YL23
E3 ubiquitin-protein ligase RNF146 (EC 6.3.2.-) (Iduna) (RING finger protein 146)Rnf146Q9CZW63
E3 ubiquitin-protein ligase RNF168 (EC 6.3.2.-) (RING finger protein 168)Rnf168Q80XJ23
E3 ubiquitin-protein ligase RNF185 (EC 6.3.2.-) (RING finger protein 185)Rnf185Q91YT23
E3 ubiquitin-protein ligase UHRF1 (EC 6.3.2.-) (Nuclear protein 95) (Nuclear zinc finger protein Np95) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (mUhrf1) (Ubiquitin-like-containing PHD and RING finger domains protein 1)Uhrf1 Np95Q8VDF23
E3 ubiquitin-protein ligase UHRF2 (EC 6.3.2.-) (NIRF) (Np95-like ring finger protein) (Nuclear protein 97) (Nuclear zinc finger protein Np97) (Ubiquitin-like PHD and RING finger domain-containing protein 2) (Ubiquitin-like-containing PHD and RING finger domains protein 2)Uhrf2 NirfQ7TMI33
Ecto-ADP-ribosyltransferase 4 (EC 2.4.2.31) (ADP-ribosyltransferase C2 and C3 toxin-like 4) (ARTC4) (Mono(ADP-ribosyl)transferase 4) (NAD(P)(+)--arginine ADP-ribosyltransferase 4) (CD antigen CD297)Art4Q9CRA03
Ectonucleoside triphosphate diphosphohydrolase 2 (NTPDase 2) (EC 3.6.1.-) (CD39 antigen-like 1) (Ecto-ATP diphosphohydrolase 2) (Ecto-ATPDase 2) (Ecto-ATPase 2)Entpd2 Cd39l1O550263
EF-hand calcium-binding domain-containing protein 4BEfcab4b Gm1073Q3UP383
EG546282 protein (Protein Gm5935)Gm5935 EG546282Q497S03
EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase)Eogt Aer61 Eogt1Q8BYW93
Elongation of very long chain fatty acids protein 2 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl2) (ELOVL fatty acid elongase 2) (ELOVL FA elongase 2) (Very-long-chain 3-oxoacyl-CoA synthase 2)Elovl2 Ssc2Q9JLJ43
Elongation of very long chain fatty acids protein 7 (EC 2.3.1.199) (3-keto acyl-CoA synthase Elovl7) (ELOVL fatty acid elongase 7) (ELOVL FA elongase 7) (Very-long-chain 3-oxoacyl-CoA synthase 7)Elovl7Q9D2Y93
Elongator complex protein 5 (Dermal papilla-derived protein 6 homolog) (Retinoic acid-induced protein 12)Elp5 Derp6 Rai12Q99L853
Embryonic polyadenylate-binding protein 2 (Embryonic poly(A)-binding protein 2) (ePABP-2) (ePABP2) (Embryonic poly(A)-binding protein type II) (Poly(A)-binding protein nuclear-like 1)Pabpn1l Epabp2 Gm1108 Pabpnl1Q5XFR03
EMI domain-containing protein 1 (Emilin and multimerin domain-containing protein 1) (Emu1)Emid1 Emu1Q91VF53
Emopamil-binding protein-like (Emopamil-binding-related protein)Ebpl Ebrp ErpQ9D0P03
Endoplasmic reticulum resident protein 29 (ERp29)Erp29P577593
Endothelial transcription factor GATA-2 (GATA-binding protein 2)Gata2O091003
Engulfment and cell motility protein 2 (Protein ced-12 homolog A)Elmo2 Kiaa1834Q8BHL53
Enhancer of polycomb homolog 1Epc1Q8C9X63
Eomesodermin homolog (T-box brain protein 2) (T-brain-2) (TBR-2)Eomes Tbr2O548393
Eph receptor A3 (Ephrin type-A receptor 3)Epha3Q8BRB13
Ephrin type-B receptor 3 (EC 2.7.10.1) (Developmental kinase 5) (mDK-5) (Tyrosine-protein kinase receptor SEK-4)Ephb3 Etk2 Mdk5 Sek4P547543
Ephrin-A5 (AL-1) (EPH-related receptor tyrosine kinase ligand 7) (LERK-7)Efna5 Epl7 Eplg7 Lerk7O085433
Ephrin-B2 (ELF-2) (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L)Efnb2 Elf2 Epl5 Eplg5 Htkl Lerk5P528003
Epididymal-specific lipocalin-10Lcn10Q810Z13
Epididymal-specific lipocalin-8 (Epididymal 17 kDa lipocalin) (EP17) (mEP17)Lcn8Q924P33
Erythroid transcription factor (Eryf1) (GATA-binding factor 1) (GATA-1) (GF-1) (NF-E1 DNA-binding protein)Gata1 Gf-1P176793
ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor)Elf2 NerfQ9JHC93
ETS-related transcription factor Elf-5 (E74-like factor 5)Elf5Q8VDK33
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a) (eRF3a) (G1 to S phase transition protein 1 homolog)Gspt1 Erf3aQ8R0503
Eukaryotic translation initiation factor 2 subunit 3, X-linked (Eukaryotic translation initiation factor 2 subunit gamma, X-linked) (eIF-2-gamma X)Eif2s3xQ9Z0N13
Eukaryotic translation initiation factor 3 subunit J-A (eIF3j-A) (Eukaryotic translation initiation factor 3 subunit 1-A) (eIF-3-alpha-A) (eIF3 p35)Eif3j1 Eif3s1-1Q3UGC73
Eukaryotic translation initiation factor 4E transporter (4E-T) (eIF4E transporter) (Eukaryotic translation initiation factor 4E nuclear import factor 1)Eif4enif1 Clast4Q9EST33
Exocyst complex component 2 (Exocyst complex component Sec5)Exoc2 Sec5 Sec5l1Q9D4H13
Exosome complex component RRP40 (EC 3.1.13.-) (Exosome component 3) (Ribosomal RNA-processing protein 40)Exosc3 Rrp40Q7TQK43
Exportin-4 (Exp4)Xpo4 Kiaa1721Q9ESJ03
Expressed sequence AA415398 (Protein AA415398)AA415398Q6P3A23
Expressed sequence CN716893 (MCG1035418) (Protein Mageb4)Mageb4 CN716893 mCG_1035418A2A9R33
F-actin-capping protein subunit alpha-3 (CapZ alpha-3) (Germ cell-specific protein 3)Capza3 Cappa3 Gsg3P701903
F-box and leucine-rich protein 22Fbxl22Q8C7B63
F-box only protein 15Fbxo15Q3TJW23
F-box only protein 40Fbxo40P629323
F-box only protein 8Fbxo8 Fbx8Q9QZN33
F-box-like/WD repeat-containing protein TBL1XR1 (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) (Transducin beta-like 1X-related protein 1)Tbl1xr1 Ira1 Tblr1Q8BHJ53
F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5)Fbxl5Q8C2S53
F-box/WD repeat-containing protein 1A (Beta-TrCP protein E3RS-IkappaB) (Beta-transducin repeat-containing protein) (Beta-TrCP) (E3RSIkappaB) (mE3RS-IkappaB) (F-box and WD repeats protein beta-TrCP) (HOS) (Ubiquitin ligase FWD1) (pIkappaB-E3 receptor subunit)Btrc Fbw1 Fbxw1 Fwd1 Kiaa4123Q3ULA23
F-box/WD repeat-containing protein 8 (F-box and WD-40 domain-containing protein 8)Fbxw8Q8BIA43
FAD-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-)Foxred1Q3TQB23
FAD-linked sulfhydryl oxidase ALR (EC 1.8.3.2) (Augmenter of liver regeneration)Gfer Alr MNCb-0663P562133
Fanconi anemia group D2 protein homolog (Protein FACD2)Fancd2Q80V623
Fanconi anemia group J protein homolog (Protein FACJ) (EC 3.6.4.13) (ATP-dependent RNA helicase BRIP1) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1)Brip1 Bach1 FancjQ5SXJ33
Fanconi anemia-associated protein of 24 kDaFaap24Q8BHL63
Farnesyl pyrophosphate synthase (FPP synthase) (FPS) (EC 2.5.1.10) ((2E,6E)-farnesyl diphosphate synthase) (Cholesterol-regulated 39 kDa protein) (CR 39) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Geranyltranstransferase)FdpsQ920E53
Fas apoptotic inhibitory molecule 1Faim Faim1Q9WUD83
FAST kinase domain-containing protein 2Fastkd2Q922E63
Fat storage-inducing transmembrane protein 1 (Fat-inducing protein 1)Fitm1 Fit1Q91V793
Fat storage-inducing transmembrane protein 2 (Fat-inducing protein 2)Fitm2 Fit2P592663
FerritinFtl1 mCG_17237Q9CPX43
Fez family zinc finger protein 2 (Forebrain embryonic zinc finger-like protein 2) (Zinc finger protein 312) (Zinc finger protein Fez-like)Fezf2 Fez Fezl Zfp312Q9ESP53
Fibroblast growth factor 17 (FGF-17)Fgf17P630753
Fibroblast growth factor 6 (FGF-6) (Heparin secretory-transforming protein 2) (HST-2) (HSTF-2) (Heparin-binding growth factor 6) (HBGF-6)Fgf6 Fgf-6 Hstf2P216583
Fibronectin leucine rich transmembrane protein 1 (MCG52071) (Protein Flrt1)Flrt1 mCG_52071Q6RKD83
Fibronectin type III domain-containing protein 3B (Factor for adipocyte differentiation 104) (HCV NS5A-binding protein 37)Fndc3b Fad104 Kiaa4164 Ns5abp37Q6NWW93
Fibronectin type III domain-containing protein 5 (Fibronectin type III repeat-containing protein 2) (Peroxisomal protein) (PeP) [Cleaved into: Irisin]Fndc5 Frcp2 PepQ8K4Z23
Fibronectin type III domain-containing protein 7Fndc7A2AED33
Fibronectin type-III domain-containing protein 3AFndc3a D14Ertd453e Fndc3 Kiaa0970Q8BX903
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)Flna Fln Fln1Q8BTM83
Flotillin-2 (Epidermal surface antigen) (ESA) (Membrane component chromosome 17 surface marker 1 homolog)Flot2 Esa1 M17s1Q606343
FLYWCH family member 2Flywch2Q9CQE93
Folate receptor 1 (Adult) (Folate receptor 1 (Adult), isoform CRA_a) (Folate receptor alpha) (Folr1 protein)Folr1 FR-alpha mCG_6770Q9R2223
Folliculin-interacting protein 1Fnip1 Kiaa1961Q68FD73
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