EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
Protein artemis (mArt) (EC 3.1.-.-) (DNA cross-link repair 1C protein) (SNM1-like protein)Dclre1c Art Snm1lQ8K4J04
Protein cornichon homolog 4 (CNIH-4) (Cornichon family AMPA receptor auxiliary protein 4)Cnih4Q9CX134
Protein CutA (Brain acetylcholinesterase putative membrane anchor)CutaQ9CQ894
Protein DDI1 homolog 2Ddi2A2ADY94
Protein Fam104aFam104a D11Wsu99eA2A6P44
Protein FAM110AFam110aQ8R1844
Protein FAM160B1Fam160b1 Kiaa1600Q8CDM84
Protein FAM207AFam207aP584684
Protein FAM214BFam214b Kiaa1539Q8BR274
Protein FAM216AFam216aQ9DB544
Protein FAM78AFam78aQ8C5524
Protein FAM92A1Fam92a1 Fam92aQ8BP224
Protein H2-T24H2-T24F8VQG44
Protein Inpp5aInpp5aE9QAS74
Protein kinase C and casein kinase substrate in neurons protein 1 (Syndapin-1)Pacsin1 PacsinQ616444
Protein LZIC (Leucine zipper and CTNNBIP1 domain-containing protein) (Leucine zipper and ICAT homologous domain-containing protein)LzicQ8K3C34
Protein Mex3aMex3aG3UYU04
Protein N-terminal asparagine amidohydrolase (EC 3.5.1.-) (Protein NH2-terminal asparagine amidohydrolase) (PNAA) (Protein NH2-terminal asparagine deamidase) (PNAD) (Protein N-terminal Asn amidase) (Protein NTN-amidase)Ntan1Q643114
Protein phosphatase 1 regulatory subunit 37 (Leucine-rich repeat-containing protein 68)Ppp1r37 Lrrc68Q8BKR54
Protein phosphatase 1 regulatory subunit 3C (Protein phosphatase 1 regulatory subunit 5) (PP1 subunit R5) (Protein targeting to glycogen) (PTG)Ppp1r3c Ppp1r5Q7TMB34
Protein PMLPmlQ609534
Protein PRRC1 (Proline-rich and coiled-coil-containing protein 1)Prrc1Q3UPH14
Protein prune homolog (EC (PRUNEM1)PruneQ8BIW14
Protein Rapgef1Rapgef1Q3UGX84
Protein RER1Rer1Q9CQU34
Protein RUFY3 (Rap2-interacting protein x) (RIPx) (Single axon-regulated protein) (Singar)Rufy3 D5Bwg0860e RipxQ9D3944
Protein shisa-5 (Scotin)Shisa5 ScotinQ9D7I04
Protein sidekick-2Sdk2 Kiaa1514Q6V4S54
Protein slowmo homolog 2Slmo2Q9CYY74
Protein strawberry notch homolog 1 (Sbno1 protein)Sbno1B2RRI24
Protein strawberry notch homolog 2Sbno2 Sno StnoQ7TNB84
Protein transport protein Sec16B (Leucine zipper transcription regulator 2) (Regucalcin gene promoter region-related protein p117) (RGPR-p117) (SEC16 homolog B)Sec16b Kiaa1928 Lztr2 RgprQ91XT44
Protein Trip11Trip11E9Q5124
Protein tyrosine phosphatase type IVA 1 (EC (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1)Ptp4a1 Prl1Q637394
Protein YIPF4 (YIP1 family member 4)Yipf4Q8C4074
Protein Zfp944Zfp944E9PUS44
Protein Zmynd8Zmynd8E9Q8D14
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha]PtmaP263504
Proto-oncogene FRAT1 (Frequently rearranged in advanced T-cell lymphomas 1) (FRAT-1)Frat1P703394
Protocadherin beta-14 (PCDH-beta-14)Pcdhb14Q6PB904
Putative E3 ubiquitin-protein ligase UBR7 (EC 6.3.2.-) (N-recognin-7)Ubr7Q8BU044
Putative homeodomain transcription factor 1Phtf1 PhtfQ9QZ094
Putative methyltransferase NSUN5 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 5) (Williams-Beuren syndrome chromosomal region 20A protein homolog)Nsun5 Wbscr20 Wbscr20aQ8K4F64
Putative RNA-binding protein 3 (RNA-binding motif protein 3)Rbm3O890864
Putative uncharacterized proteinCes1f AU018778Q3UWB14
Putative uncharacterized proteinZfp951Q3V1G74
Putative uncharacterized proteinTdgf1Q3UZP84
Putative uncharacterized protein (Fragment)Dusp16Q3UMM54
Pyridoxal kinase (EC (Pyridoxine kinase)Pdxk PkhQ8K1834
Rab GTPase-activating protein 1 (GAP and centrosome-associated protein) (Rab6 GTPase-activating protein GAPCenA)Rabgap1 Kiaa4104A2AWA94
RAC-gamma serine/threonine-protein kinase (EC (Protein kinase Akt-3) (Protein kinase B gamma) (PKB gamma) (RAC-PK-gamma)Akt3Q9WUA64
Radial spoke head protein 3 homolog A (Radial spoke head-like protein 2A)Rsph3a Rshl2 Rshl2aQ3UFY44
Ran-binding protein 3-likeRanbp3lQ6PDH44
Ras-like protein family member 12Rasl12Q08AT14
Ras-related C3 botulinum toxin substrate 1 (p21-Rac1)Rac1P630014
Ras-related protein Rab-1A (YPT1-related protein)Rab1A Rab1P628214
Ras-related protein Rab-3ARab3aP630114
Ras-related protein Rap-1A (Ras-related protein Krev-1)Rap1a Krev-1P628354
RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (FAK family kinase-interacting protein of 200 kDa) (FIP200) (LaXp180)Rb1cc1 Cc1 Kiaa0203Q9ESK94
Reactive oxygen species modulator 1 (ROS modulator 1) (Protein MGR2 homolog)Romo1P606034
Receptor expression-enhancing protein 1Reep1 D6Ertd253eQ8BGH44
Receptor-type tyrosine-protein phosphatase epsilon (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon) (EC PtpeP494464
Regulator of G-protein signaling 18 (RGS18)Rgs18Q99PG44
Replication factor C subunit 2 (Activator 1 40 kDa subunit) (A1 40 kDa subunit) (Activator 1 subunit 2) (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40)Rfc2Q9WUK44
REST corepressor 3Rcor3Q6PGA04
Retinoic acid receptor responder protein 2Rarres2Q9DD064
Rho GDP-dissociation inhibitor 2 (Rho GDI 2) (D4) (Rho-GDI beta)Arhgdib Gdid4Q615994
Rho GTPase-activating protein 32 (Brain-specific Rho GTPase-activating protein) (GAB-associated Cdc42/Rac GTPase-activating protein) (GC-GAP) (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS) (RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling) (p200RhoGAP) (p250GAP)Arhgap32 Grit Kiaa0712 RicsQ811P84
Rho guanine nucleotide exchange factor 2 (Guanine nucleotide exchange factor H1) (GEF-H1) (LBC'S first cousin) (Lymphoid blast crisis-like 1) (Oncogene LFC) (Rhobin)Arhgef2 Kiaa0651 Lbcl1 LfcQ608754
Rho-associated protein kinase 1 (EC (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)Rock1P703354
Rho-related GTP-binding protein RhoDRhod Arhd RhomP973484
Rhomboid-related protein 2 (RRP2) (EC [Cleaved into: Rhomboid-related protein 2, N-terminal fragment (NTF); Rhomboid-related protein 2, C-terminal fragment (CTF)]Rhbdl2A2AGA44
Ribonuclease P protein subunit p21 (RNaseP protein p21) (EC (Ribonucleoprotein V)Rpp21 Cat60Q8R0404
Ribonuclease T2 (EC 3.1.27.-) (Ribonuclease 6)Rnaset2 Rnase6plQ9CQ014
Ribosome biogenesis protein NSA2 homolog (L-name-related protein 42) (LNR42) (TGF-beta-inducible nuclear protein 1)Nsa2 Tinp1Q9CR474
Ribosome biogenesis protein WDR12 (WD repeat-containing protein 12)Wdr12 MNCb-5414Q9JJA44
Ribosome-binding protein 1 (Ribosome receptor protein) (RRp) (mRRp)Rrbp1Q99PL54
Ribulose-phosphate 3-epimerase (EC (Ribulose-5-phosphate-epimerase)RpeQ8VEE04
RILP-like protein 1 (Rab-interacting lysosomal-like protein 1)Rilpl1 MNCb-2440Q9JJC64
RNA binding motif protein, X-linked-like-1 (Heterogeneous nuclear ribonucleoprotein G-like 1) (RNA binding motif protein, X chromosome retrogene)Rbmxl1 RbmxrtQ91VM54
RNA polymerase-associated protein RTF1 homologRtf1A2AQ194
RNA-binding protein Raly (Maternally-expressed hnRNP C-related protein) (hnRNP associated with lethal yellow protein)Raly MercQ640124
Roquin-2 (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2)Rc3h2 MnabP0C0904
RPA-interacting proteinRpain RipQ9CWY94
RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE)Rufy2 Kiaa1537Q8R4C24
RUN domain-containing protein 1Rundc1Q0VDN74
S-methyl-5'-thioadenosine phosphorylase (EC (5'-methylthioadenosine phosphorylase) (MTA phosphorylase) (MTAP) (MTAPase)MtapQ9CQ654
Saccharopine dehydrogenase-like oxidoreductase (EC 1.-.-.-)SccpdhQ8R1274
SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1) (SH3 protein expressed in lymphocytes 2) (SH3-lymphocyte protein 2) (SLy2)Samsn1P577254
Scavenger receptor class B member 1 (SRB1) (SR-BI)Scarb1 Srb1Q610094
Scm-like with four MBT domains protein 1Sfmbt1Q9JMD14
Secretory carrier-associated membrane protein 4 (SC4) (Secretory carrier membrane protein 4)Scamp4Q9JKV54
Securin (Pituitary tumor-transforming gene 1 protein)Pttg1 PttgQ9CQJ74
Selenium-binding protein 1 (56 kDa selenium-binding protein) (SBP56) (SP56)Selenbp1 LpsbP175634
Selenoprotein H (SelH)SelhQ3UQA74
Selenoprotein K (SelK)SelkQ9JLJ14
Selenoprotein W (SelW)Sepw1 SelwP633004
Semaphorin-6B (Semaphorin VIB) (Sema VIB) (Semaphorin-N) (Sema N)Sema6b SemanO549514
Sentrin-specific protease 3 (EC (SUMO-1-specific protease 3) (Sentrin/SUMO-specific protease SENP3) (Smt3-specific isopeptidase 1) (Smt3ip1)Senp3 Smt3ip Smt3ip1Q9EP974
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