EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
Calcium-binding protein 1 (CaBP1)Cabp1Q9JLK73
Calcium-binding protein 39 (MO25alpha) (Protein Mo25)Cab39 Mo25Q061383
Calcium-binding protein 5 (CaBP5)Cabp5Q9JLK33
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Cam-PDE 1C) (EC
Calcium/calmodulin-dependent protein kinase type 1 (EC (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha)Camk1Q91YS83
Calcium/calmodulin-dependent protein kinase type 1D (EC (CaM kinase I delta) (CaM-KI delta) (CaMKI delta) (CaM kinase ID) (CaMKI-like protein kinase) (CKLiK) (mCKLiK)Camk1dQ8BW963
Calponin-1 (Basic calponin) (Calponin H1, smooth muscle)Cnn1Q080913
Calretinin (CR)Calb2Q083313
cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC PkacaP051323
cAMP-regulated phosphoprotein 21 (ARPP-21) (Regulator of calmodulin signaling) (Thymocyte cAMP-regulated phosphoprotein)Arpp21 Rcs TarppQ9DCB43
cAMP-responsive element modulatorCremP276993
Cannabinoid receptor 2 (CB-2) (CB2) (mCB2)Cnr2P479363
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.-) (Cap methyltransferase 2) (Cap2 2'O-ribose methyltransferase 2) (MTr2) (FtsJ methyltransferase domain-containing protein 1)Cmtr2 Ftsjd1Q8BWQ43
Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase, isoform CRA_c) (DNA fragmentation factor subunit beta)Cad mCG_23490B2RQC63
Carboxylesterase 1C (EC (Liver carboxylesterase N) (Lung surfactant convertase) (PES-N)Ces1c Es1P239533
Carboxylesterase 1E (EC (Egasyn) (Liver carboxylesterase 22) (Es-22) (Esterase-22)Ces1e Es22Q641763
Carboxypeptidase A5 (EC
Cartilage-associated proteinCrtap CaspQ9CYD33
Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC
Casein kinase II subunit alpha' (CK II alpha') (EC
CASP8 and FADD-like apoptosis regulator (Caspase homolog) (CASH) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (Cellular FLICE-like inhibitory protein) (c-FLIP) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Inhibitor of FLICE) (I-FLICE) (MACH-related inducer of toxicity) (MRIT) (Usurpin) [Cleaved into: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12]Cflar CashO357323
Caspase activity and apoptosis inhibitor 1 (Conserved anti-apoptotic protein) (CAAP)Caap1 CaapQ8VDY93
Cation-dependent mannose-6-phosphate receptor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46)M6pr 46mprP246683
Cbp/p300-interacting transactivator 1 (Melanocyte-specific protein 1)Cited1 Msg1P977693
CCA tRNA nucleotidyltransferase 1, mitochondrial (EC (mitochondrial tRNA nucleotidyl transferase, CCA-adding) (mt CCA-adding enzyme) (mt tRNA CCA-diphosphorylase) (mt tRNA CCA-pyrophosphorylase) (mt tRNA adenylyltransferase)Trnt1Q8K1J63
CCR4-NOT transcription complex subunit 10Cnot10Q8BH153
CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3)Cnot3 Not3Q8K0V43
CD151 antigen (GP27) (Membrane glycoprotein SFA-1) (Platelet-endothelial tetraspan antigen 3) (PETA-3) (CD antigen CD151)Cd151 Peta3O355663
CD160 antigen (Natural killer cell receptor BY55) (CD antigen CD160)Cd160 By55O888753
CD209 antigen-like protein C (DC-SIGN-related protein 2) (DC-SIGNR2) (CD antigen CD209)Cd209cQ91ZW93
CD209 antigen-like protein D (DC-SIGN-related protein 3) (DC-SIGNR3) (CD antigen CD209)Cd209dQ91ZW83
cDNA sequence BC066107Zfp870 BC066107 mCG_1051120Q6NZJ33
Cell adhesion molecule-related/down-regulated by oncogenesCdon CdoQ32MD93
Cell cycle progression protein 1Ccpg1Q640L33
Cell division cycle-associated protein 3 (Gene-rich cluster protein C8) (Trigger of mitotic entry protein 1) (TOME-1)Cdca3 C8 Grcc8 Tome1Q99M543
Cell surface glycoprotein CD200 receptor 3 (CD200 cell surface glycoprotein receptor-like 3) (CD200 receptor-like 3) (CD200 cell surface glycoprotein receptor-like b) (CD200RLb) (Cell surface glycoprotein OX2 receptor 3)Cd200r3 Cd200rlbQ5UKY43
Cell surface glycoprotein MUC18 (Gicerin) (Melanoma cell adhesion molecule) (Melanoma-associated antigen MUC18) (CD antigen CD146)Mcam Muc18Q8R2Y23
Centrin-2 (Caltractin isoform 1)Cetn2 CaltQ9R1K93
Centromere protein R (CENP-R) (Nuclear receptor-interacting factor 3)Itgb3bp Cenpr Nrif3Q9CQ823
Centromere/kinetochore protein zw10 homologZw10O546923
Centrosomal protein of 89 kDa (Cep89) (Coiled-coil domain-containing protein 123)Cep89 Ccdc123Q9CZX23
Ceramide synthase 4 (CerS4) (LAG1 longevity assurance homolog 4) (Translocating chain-associating membrane protein homolog 1) (TRAM homolog 1)Cers4 Lass4 Trh1Q9D6J13
Cerebral cavernous malformations 2 protein-like (CCM2-like)Ccm2lQ8VCC63
Charged multivesicular body protein 5 (Chromatin-modifying protein 5) (SNF7 domain-containing protein 2)Chmp5 Snf7dc2Q9D7S93
Chemokine-like factorCklfQ9DAS13
Chloride intracellular channel protein 4 (mc3s5/mtCLIC)Clic4Q9QYB13
Choline acetyltransferase (SH2 domain-containing protein 3C)ChatQ8BQV23
Chromaffin granule amine transporter (Solute carrier family 18 member 1) (Vesicular amine transporter 1) (VAT1)Slc18a1 Vmat1Q8R0903
Chromatin accessibility complex protein 1 (CHRAC-1) (DNA polymerase epsilon subunit p15) (NF-YC-like protein) (YC-like protein 1) (YCL1)Chrac1Q9JKP83
Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-I p150)Chaf1a Caip150Q9QWF03
Chromatin complexes subunit BAP18 (BPTF-associated protein of 18 kDa)Bap18Q9DCT63
Chromobox protein homolog 2 (M33) (Modifier 3 protein)Cbx2 M33P306583
Chromobox protein homolog 6Cbx6Q9DBY53
Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (mPc3)Cbx8 Pc3Q9QXV13
Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC (ATP-dependent helicase CHD1)Chd1 Chd-1P402013
Cingulin-like protein 1 (Junction-associated coiled-coil protein)Cgnl1 Jacop Kiaa1749Q6AW693
Class E basic helix-loop-helix protein 22 (bHLHe22) (Class B basic helix-loop-helix protein 5) (bHLHb5) (Protein BETA3)Bhlhe22 Bhlhb5Q8C6A83
Clathrin light chain B (Lcb)CltbQ6IRU53
Clavesin-1 (Retinaldehyde-binding protein 1-like 1)Clvs1 Rlbp1l1Q9D4C93
Cleavage and polyadenylation factor subunit homolog (S. cerevisiae) (Protein Pcf11)Pcf11 mCG_8209G3X9Z43
Cleavage and polyadenylation specificity factor subunit 3 (EC 3.1.27.-) (Cleavage and polyadenylation specificity factor 73 kDa subunit) (CPSF 73 kDa subunit) (mRNA 3'-end-processing endonuclease CPSF-73)Cpsf3 Cpsf73Q9QXK73
Cleft lip and palate transmembrane protein 1-like protein (CLPTM1-like protein)Clptm1lQ8BXA53
CLK4-associating serine/arginine rich protein (Clk4-associating SR-related protein) (Serine/arginine-rich splicing factor 16) (Splicing factor, arginine/serine-rich 16) (Suppressor of white-apricot homolog 2)Clasrp Clasp Sfrs16 Srsf16 Swap2Q8CFC73
Clusterin (Apolipoprotein J) (Apo-J) (Clustrin) (Sulfated glycoprotein 2) (SGP-2) [Cleaved into: Clusterin beta chain; Clusterin alpha chain]Clu Apoj Msgp-2Q068903
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 (Alpha 2,3-ST 2) (Beta-galactoside alpha-2,3-sialyltransferase 2) (EC (Gal-NAc6S) (Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase) (ST3Gal II) (ST3GalII) (ST3GalA.2) (Sialyltransferase 4B) (SIAT4-B)St3gal2 Siat4b Siat5Q112043
CMP-sialic acid transporter (CMP-SA-Tr) (CMP-Sia-Tr) (Solute carrier family 35 member A1)Slc35a1Q614203
CMRF35-like molecule 1 (CLM-1) (CD300 antigen-like family member F) (Leukocyte mono-Ig-like receptor 3) (Myeloid-associated immunoglobulin-like receptor 5) (MAIR-5) (MAIR-V) (CD antigen CD300f)Cd300lf Clm1 Lmir3Q6SJQ73
Cochlin (COCH-5B2)CochQ625073
Coenzyme Q-binding protein COQ10 homolog B, mitochondrialCoq10bQ3THF93
Coiled-coil domain-containing protein 27Ccdc27 Gm1035Q3V0363
Coiled-coil domain-containing protein 39Ccdc39 D3Ertd789eQ9D5Y13
Coiled-coil domain-containing protein 40 (Protein links)Ccdc40 LnksQ8BI793
Coiled-coil domain-containing protein 47 (Adipocyte-specific protein 4)Ccdc47 Asp4Q9D0243
Coiled-coil domain-containing protein 91 (GGA-binding partner)Ccdc91 GgabpQ9D8L53
Coiled-coil domain-containing protein C1orf110 homolog0Q3URK13
Coiled-coil-helix-coiled-coil-helix domain containing 10 (Nur77 downstream gene 2) (Nur77 downstream protein 2) (Protein Chchd10)Chchd10 Ndg2 mCG_3110Q7TNL93
Coiled-coil-helix-coiled-coil-helix domain-containing protein 5Chchd5Q9CQP33
Collagen alpha-1(XXIV) chainCol24a1Q30D773
Collagen alpha-1(XXV) chain (CLAC-P) [Cleaved into: Collagen-like Alzheimer amyloid plaque component (CLAC)]Col25a1Q99MQ53
Collagen alpha-1(XXVII) chainCol27a1 Kiaa1870Q5QNQ93
Collagen alpha-2(VI) chainCol6a2Q027883
Collagenase 3 (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13)Mmp13P334353
COMM domain-containing protein 1 (Protein Murr1)Commd1 Murr1Q8K4M53
COMM domain-containing protein 5Commd5Q8R3953
COMM domain-containing protein 6Commd6Q3V4B53
COMM domain-containing protein 8Commd8Q9CZG33
Complement C1q tumor necrosis factor-related protein 3 (Collagenous repeat-containing sequence 26 kDa protein) (CORS26) (Secretory protein CORS26)C1qtnf3 Cors26 Ctrp3Q9ES303
Complement C1s-B subcomponent (EC (C1 esterase) (Complement component 1 subcomponent s-B) [Cleaved into: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain]C1sb C1s Gm5077Q8CFG83
Complement component receptor 1-like protein (Complement regulatory protein Crry) (Protein p65)Cr1l Crry CryQ647353
Complement decay-accelerating factor, GPI-anchored (DAF-GPI) (CD antigen CD55)Cd55 Cd55a Daf Daf1Q614753
Complex I intermediate-associated protein 30, mitochondrial (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1)Ndufaf1 Cia30Q9CWX23
Complexin-4 (Complexin IV) (CPX IV)Cplx4Q80WM33
Condensin complex subunit 2 (Barren homolog protein 1) (Chromosome-associated protein H) (mCAP-H) (Non-SMC condensin I complex subunit H) (XCAP-H homolog)Ncaph Brrn Brrn1 CaphQ8C1563
Connector enhancer of kinase suppressor of ras 3 (Connector enhancer of KSR 3) (CNK homolog protein 3) (CNK3) (CNKSR family member 3) (Maguin-like protein)Cnksr3Q8BMA33
Contactin-4 (Brain-derived immunoglobulin superfamily protein 2) (BIG-2)Cntn4 Kiaa3024Q69Z263
Contactin-associated protein like 5-1 (Cell recognition molecule Caspr5-1) (Cell recognition molecule Caspr5a) (Contactin-associated protein-like 5a)Cntnap5a Caspr5-1Q0V8T93
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