EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma)PTPRSQ1333251
Replication factor C subunit 4 (Activator 1 37 kDa subunit) (A1 37 kDa subunit) (Activator 1 subunit 4) (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37)RFC4P3524951
Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)RPS6KA3 ISPK1 MAPKAPK1B RSK2P5181251
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)SRRM2 KIAA0324 SRL300 SRM300 HSPC075Q9UQ3551
Serum deprivation-response protein (Cavin-2) (PS-p68) (Phosphatidylserine-binding protein)SDPRO9581051
Signal recognition particle 19 kDa protein (SRP19)SRP19P0913251
Splicing factor 3B subunit 4 (Pre-mRNA-splicing factor SF3b 49 kDa subunit) (SF3b50) (Spliceosome-associated protein 49) (SAP 49)SF3B4 SAP49Q1542751
Syntaxin-2 (Epimorphin)STX2 EPIM STX2A STX2B STX2CP3285651
Transmembrane protein 43 (Protein LUMA)TMEM43 UNQ2564/PRO6244Q9BTV451
Tropomyosin beta chain (Beta-tropomyosin) (Tropomyosin-2)TPM2 TMSBP0795151
Up-regulated during skeletal muscle growth protein 5 (Diabetes-associated protein in insulin-sensitive tissues) (HCV F-transactivated protein 2)USMG5 DAPIT HCVFTP2 PD04912Q96IX551
(E3-independent) E2 ubiquitin-conjugating enzyme (EC (E2/E3 hybrid ubiquitin-protein ligase UBE2O) (Ubiquitin carrier protein O) (Ubiquitin-conjugating enzyme E2 O) (Ubiquitin-conjugating enzyme E2 of 230 kDa) (Ubiquitin-conjugating enzyme E2-230K) (Ubiquitin-protein ligase O)UBE2O KIAA1734Q9C0C950
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)ABI2 ARGBPIAQ9NYB950
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 (EC (ADP-ribosyl cyclase 2) (Bone marrow stromal antigen 1) (BST-1) (Cyclic ADP-ribose hydrolase 2) (cADPr hydrolase 2) (CD antigen CD157)BST1Q1058850
Aldehyde dehydrogenase family 3 member B1 (EC (Aldehyde dehydrogenase 7)ALDH3B1 ALDH7P4335350
Beta-parvin (Affixin)PARVB CGI-56Q9HBI150
BRCA1-A complex subunit BRE (BRCA1/BRCA2-containing complex subunit 45) (Brain and reproductive organ-expressed protein)BRE BRCC45Q9NXR750
CAP-Gly domain-containing linker protein 1 (Cytoplasmic linker protein 1) (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed-Sternberg intermediate filament-associated protein) (Restin)CLIP1 CYLN1 RSNP3062250
Collagen alpha-1(XV) chain [Cleaved into: Restin (Endostatin-XV) (Related to endostatin) (Restin-I); Restin-2 (Restin-II); Restin-3 (Restin-III); Restin-4 (Restin-IV)]COL15A1P3905950
DCN1-like protein 1 (DCUN1 domain-containing protein 1) (Defective in cullin neddylation protein 1-like protein 1) (Squamous cell carcinoma-related oncogene)DCUN1D1 DCUN1L1 RP42 SCCROQ96GG950
dCTP pyrophosphatase 1 (EC (Deoxycytidine-triphosphatase 1) (dCTPase 1) (RS21C6) (XTP3-transactivated gene A protein)DCTPP1 XTP3TPA CDA03Q9H77350
Discoidin, CUB and LCCL domain-containing protein 2 (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1) (Endothelial and smooth muscle cell-derived neuropilin-like protein)DCBLD2 CLCP1 ESDNQ96PD250
Endoplasmic reticulum aminopeptidase 1 (EC 3.4.11.-) (ARTS-1) (Adipocyte-derived leucine aminopeptidase) (A-LAP) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP) (Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator)ERAP1 APPILS ARTS1 KIAA0525 UNQ584/PRO1154Q9NZ0850
Epsin-1 (EH domain-binding mitotic phosphoprotein) (EPS-15-interacting protein 1)EPN1Q9Y6I350
Exocyst complex component 3 (Exocyst complex component Sec6)EXOC3 SEC6 SEC6L1O6064550
Exocyst complex component 5 (Exocyst complex component Sec10) (hSec10)EXOC5 SEC10 SEC10L1O0047150
Fibulin-2 (FIBL-2)FBLN2P9809550
Glutamate-rich WD repeat-containing protein 1GRWD1 GRWD KIAA1942 WDR28Q9BQ6750
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2) (Spermatogenic glyceraldehyde-3-phosphate dehydrogenase)GAPDHS GAPD2 GAPDH2 GAPDS HSD-35 HSD35O1455650
Golgin subfamily B member 1 (372 kDa Golgi complex-associated protein) (GCP372) (Giantin) (Macrogolgin)GOLGB1Q1478950
GrancalcinGCA GCLP2867650
Histone deacetylase 1 (HD1) (EC RPD3L1Q1354750
Immunoglobulin kappa variable 1D-33 (Ig kappa chain V-I region AG) (Ig kappa chain V-I region Bi) (Ig kappa chain V-I region Lay) (Ig kappa chain V-I region Ni) (Ig kappa chain V-I region Rei) (Ig kappa chain V-I region Roy) (Ig kappa chain V-I region Scw) (Ig kappa chain V-I region WAT)IGKV1D-33P0159350
Interleukin-1 receptor accessory protein (IL-1 receptor accessory protein) (IL-1RAcP) (Interleukin-1 receptor 3) (IL-1R-3) (IL-1R3)IL1RAP C3orf13 IL1R3Q9NPH350
Keratin, type II cytoskeletal 75 (Cytokeratin-75) (CK-75) (Keratin-6 hair follicle) (hK6hf) (Keratin-75) (K75) (Type II keratin-K6hf) (Type-II keratin Kb18)KRT75 K6HF KB18O9567850
Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2)PPFIBP1 KIAA1230Q86W9250
Methylosome subunit pICln (Chloride channel, nucleotide sensitive 1A) (Chloride conductance regulatory protein ICln) (I(Cln)) (Chloride ion current inducer protein) (ClCI) (Reticulocyte pICln)CLNS1A CLCI ICLNP5410550
Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC (Mediator of RhoA-dependent invasion) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)MRI1 MRDI UNQ6390/PRO21135Q9BV2050
Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)MAPK14 CSBP CSBP1 CSBP2 CSPB1 MXI2 SAPK2AQ1653950
Mucin-5B (MUC-5B) (Cervical mucin) (High molecular weight salivary mucin MG1) (Mucin-5 subtype B, tracheobronchial) (Sublingual gland mucin)MUC5B MUC5Q9HC8450
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (Complex I subunit B13) (Complex I-13kD-B) (CI-13kD-B) (NADH-ubiquinone oxidoreductase 13 kDa-B subunit)NDUFA5Q1671850
Nitrilase homolog 1 (EC 3.5.-.-)NIT1Q86X7650
Oligoribonuclease, mitochondrial (EC 3.1.-.-) (RNA exonuclease 2 homolog) (Small fragment nuclease)REXO2 SFN SMFN CGI-114Q9Y3B850
Peptidyl-glycine alpha-amidating monooxygenase (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (PHM) (EC; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC (Peptidylamidoglycolate lyase) (PAL)]PAMP1902150
Phospholipid phosphatase 1 (EC (Lipid phosphate phosphohydrolase 1) (PAP2-alpha) (Phosphatidate phosphohydrolase type 2a) (Phosphatidic acid phosphatase 2a) (PAP-2a) (PAP2a)PLPP1 LPP1 PPAP2AO1449450
Plakophilin-1 (Band 6 protein) (B6P)PKP1Q1383550
Plexin-D1PLXND1 KIAA0620Q9Y4D750
PRA1 family protein 2PRAF2 JM4O6083150
Protein furry homolog-like (ALL1-fused gene from chromosome 4p12 protein)FRYL AF4P12 KIAA0826O9491550
Protein phosphatase 1G (EC (Protein phosphatase 1C) (Protein phosphatase 2C isoform gamma) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma)PPM1G PPM1CO1535550
Rab3 GTPase-activating protein non-catalytic subunit (RGAP-iso) (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit)RAB3GAP2 KIAA0839Q9H2M950
Ribosomal RNA small subunit methyltransferase NEP1 (EC 2.1.1.-) (18S rRNA (pseudouridine(1248)-N1)-methyltransferase) (18S rRNA Psi1248 methyltransferase) (Nucleolar protein EMG1 homolog) (Protein C2f) (Ribosome biogenesis protein NEP1)EMG1 C2FQ9297950
Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter) (Sodium/myo-inositol transporter 1) (SMIT1) (Solute carrier family 5 member 3)SLC5A3P5379450
Sortilin (100 kDa NT receptor) (Glycoprotein 95) (Gp95) (Neurotensin receptor 3) (NT3) (NTR3)SORT1Q9952350
SPARC (Basement-membrane protein 40) (BM-40) (Osteonectin) (ON) (Secreted protein acidic and rich in cysteine)SPARC ONP0948650
Splicing factor U2AF 35 kDa subunit-like protein (U2 small nuclear RNA auxiliary factor 1-like protein 5)U2AF1L5P0DN7650
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial (EC (GTP-specific succinyl-CoA synthetase subunit beta) (G-SCS) (GTPSCS) (Succinyl-CoA synthetase beta-G chain) (SCS-betaG)SUCLG2Q96I9950
Tetratricopeptide repeat protein 37 (TPR repeat protein 37) (SKI3 homolog) (Ski3) (Tricho-hepatic-enteric syndrome protein) (Thespin)TTC37 KIAA0372Q6PGP750
Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta)EIF2B4 EIF2BDQ9UI1050
Tyrosine-protein kinase Lck (EC (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)LCKP0623950
Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) (ThiFP1) (UFM1-activating enzyme) (Ubiquitin-activating enzyme E1 domain-containing protein 1)UBA5 UBE1DC1Q9GZZ950
Villin-1VIL1 VILP0932750
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)PLCB4Q1514749
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 (EC (Phosphoinositide phospholipase C-delta-3) (Phospholipase C-delta-3) (PLC-delta-3)PLCD3 KIAA1964Q8N3E949
55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1)MPP1 DXS552E EMP55Q0001349
Adhesion G protein-coupled receptor L2 (Calcium-independent alpha-latrotoxin receptor 2) (CIRL-2) (Latrophilin homolog 1) (Latrophilin-2) (Lectomedin-1)ADGRL2 KIAA0786 LEC1 LPHH1 LPHN2O9549049
Apolipoprotein(a) (Apo(a)) (Lp(a)) (EC 3.4.21.-)LPAP0851949
ATP-dependent RNA helicase DDX18 (EC (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb)DDX18 cPERP-DQ9NVP149
Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC-1 subunit 1) (GCN5-like protein 1) (Protein RT14)BLOC1S1 BLOS1 GCN5L1 RT14P7853749
Calcium-binding mitochondrial carrier protein Aralar2 (Citrin) (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13)SLC25A13 ARALAR2Q9UJS049
Clustered mitochondria protein homologCLUH KIAA0664O7515349
Condensin complex subunit 3 (Chromosome-associated protein G) (Condensin subunit CAP-G) (hCAP-G) (Melanoma antigen NY-MEL-3) (Non-SMC condensin I complex subunit G) (XCAP-G homolog)NCAPG CAPG NYMEL3Q9BPX349
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC POLR2P2492849
ES1 protein homolog, mitochondrial (Protein GT335) (Protein KNP-I)C21orf33 HES1 KNPIP3004249
Eukaryotic translation initiation factor 4B (eIF-4B)EIF4BP2358849
Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog) (hMtr3) (p11)EXOSC6 MTR3Q5RKV649
Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand)GAS6 AXLLGQ1439349
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10GNG10 GNGT10P5015149
Heat shock 70 kDa protein 13 (Microsomal stress-70 protein ATPase core) (Stress-70 protein chaperone microsome-associated 60 kDa protein)HSPA13 STCHP4872349
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]KPNA1 RCH2P5229449
Insulin-like growth factor 1 receptor (EC (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]IGF1RP0806949
Isoleucine--tRNA ligase, mitochondrial (EC (Isoleucyl-tRNA synthetase) (IleRS)IARS2Q9NSE449
Mediator of RNA polymerase II transcription subunit 30 (Mediator complex subunit 30) (TRAP/Mediator complex component TRAP25) (Thyroid hormone receptor-associated protein 6) (Thyroid hormone receptor-associated protein complex 25 kDa component) (Trap25)MED30 THRAP6 TRAP25Q96HR349
Mitochondrial import inner membrane translocase subunit Tim13TIMM13 TIM13B TIMM13A TIMM13BQ9Y5L449
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (Complex I-PDSW) (CI-PDSW) (NADH-ubiquinone oxidoreductase PDSW subunit)NDUFB10O9600049
Neurolysin, mitochondrial (EC (Angiotensin-binding protein) (Microsomal endopeptidase) (MEP) (Mitochondrial oligopeptidase M) (Neurotensin endopeptidase)NLN AGTBP KIAA1226Q9BYT849
NudC domain-containing protein 2NUDCD2Q8WVJ249
Pachytene checkpoint protein 2 homolog (Human papillomavirus type 16 E1 protein-binding protein) (16E1-BP) (HPV16 E1 protein-binding protein) (Thyroid hormone receptor interactor 13) (Thyroid receptor-interacting protein 13) (TR-interacting protein 13) (TRIP-13)TRIP13 PCH2Q1564549
Paraspeckle component 1 (Paraspeckle protein 1)PSPC1 PSP1Q8WXF149
Protein LSM12 homologLSM12Q3MHD249
Putative peptidyl-tRNA hydrolase PTRHD1 (EC (Peptidyl-tRNA hydrolase domain-containing protein 1)PTRHD1 C2orf79Q6GMV349
Pyrroline-5-carboxylate reductase 2 (P5C reductase 2) (P5CR 2) (EC
Rho GTPase-activating protein 18 (MacGAP) (Rho-type GTPase-activating protein 18)ARHGAP18Q8N39249
Serrate RNA effector molecule homolog (Arsenite-resistance protein 2)SRRT ARS2 ASR2Q9BXP549
Serum amyloid A-4 protein (Constitutively expressed serum amyloid A protein) (C-SAA)SAA4 CSAAP3554249
Signal transducer and activator of transcription 2 (p113)STAT2P5263049
Sushi domain-containing protein 2SUSD2Q9UGT449
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H)SMARCA5 SNF2H WCRF135O6026449
Synaptosomal-associated protein 29 (SNAP-29) (Soluble 29 kDa NSF attachment protein) (Vesicle-membrane fusion protein SNAP-29)SNAP29O9572149
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