EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
ATP-dependent RNA helicase ADhx9E9QNN18
Basement membrane-specific heparan sulfate proteoglycan core proteinHspg2B1B0C78
Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin-2)Sntb1 Snt2b1Q99L888
Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC]PnkpQ9JLV68
Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC (Activin receptor-like kinase 3) (ALK-3) (BMP-2/BMP-4 receptor) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)Bmpr1a Acvrlk3 BmprP368958
Bridging integrator 2Bin2D3Z6Q98
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (mBACURD3) (BTB/POZ domain-containing protein KCTD10)Kctd10Q922M38
Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH)Capn7 PalbhQ9R1S88
Carbonic anhydrase 14 (EC (Carbonate dehydratase XIV) (Carbonic anhydrase XIV) (CA-XIV)Ca14 Car14 CatmQ9WVT68
Carboxylesterase 1C (EC (Liver carboxylesterase N) (Lung surfactant convertase) (PES-N)Ces1c Es1P239538
Carboxypeptidase N catalytic chain (CPN) (EC (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit)Cpn1Q9JJN58
Casein kinase I isoform delta (CKI-delta) (CKId) (EC (Tau-protein kinase CSNK1D) (EC HckidQ9DC288
Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC
Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC
Catechol O-methyltransferase (EC Comt1O885878
Cathelicidin antimicrobial peptide (Cathelin-like protein) (CLP) [Cleaved into: Cathelin-related antimicrobial peptide (Cramp)]Camp Cnlp CrampP514378
Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TR-interacting protein 10) (TRIP-10)Trip10 Cip4Q8CJ538
Cell growth-regulating nucleolar protein (Protein expressed in male leptotene and zygotene spermatocytes 264) (MLZ-264)LyarQ082888
Cerebral cavernous malformations protein 2 homolog (Malcavernin) (Osmosensing scaffold for MEKK3)Ccm2 OsmQ8K2Y98
Charged multivesicular body protein 1b-2 (Chromatin-modifying protein 1b-2) (CHMP1b-2)Chmp1b2Q9CQD48
Clathrin light chainCltaB1AWE08
Cleavage and polyadenylation specificity factor subunit 6Cpsf6Q6NVF98
Clustered mitochondria protein homologCluh Kiaa0664Q5SW198
Copper transport protein ATOX1 (Metal transport protein ATX1)Atox1O089978
Copper-transporting ATPase 1 (EC (Copper pump 1) (Menkes disease-associated protein homolog)Atp7a MnkQ644308
Crk-like proteinCrkl CrkolP479418
CUGBP Elav-like family member 1 (CELF-1) (50 kDa nuclear polyadenylated RNA-binding protein) (Brain protein F41) (Bruno-like protein 2) (CUG triplet repeat RNA-binding protein 1) (CUG-BP1) (CUG-BP- and ETR-3-like factor 1) (Deadenylation factor CUG-BP) (Deadenylation factor EDEN-BP) (Embryo deadenylation element-binding protein homolog) (EDEN-BP homolog) (RNA-binding protein BRUNOL-2)Celf1 Brunol2 Cugbp Cugbp1P286598
Cullin-2 (CUL-2)Cul2Q9D4H88
Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (TBP-interacting protein of 120 kDa B) (TBP-interacting protein 120B) (p120 CAND2)Cand2 Kiaa0667 Tip120bQ6ZQ738
Cyclin-dependent kinase 18 (EC (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3)Cdk18 Pctaire3 Pctk3Q048998
Cysteine and histidine-rich domain-containing protein 1 (CHORD domain-containing protein 1) (CHORD-containing protein 1) (Chp-1) (Protein morgana)Chordc1 Chp1 MorganaQ9D1P48
Cytochrome c oxidase subunit NDUFA4Ndufa4Q624258
Cytosolic 5'-nucleotidase 3A (EC (7-methylguanosine phosphate-specific 5'-nucleotidase) (7-methylguanosine nucleotidase) (EC (Cytosolic 5'-nucleotidase 3) (Cytosolic 5'-nucleotidase III) (cN-III) (Lupin) (Pyrimidine 5'-nucleotidase 1) (P5'N-1) (P5N-1) (PN-I)Nt5c3a Nt5c3Q9D0208
Dedicator of cytokinesis protein 8Dock8Q8C1478
Dihydropteridine reductase (EC (HDHPR) (Quinoid dihydropteridine reductase)Qdpr DhprQ8BVI48
Disintegrin and metalloproteinase domain-containing protein 15 (ADAM 15) (EC 3.4.24.-) (AD56) (Metalloprotease RGD disintegrin protein) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15) (MDC-15) (Metargidin)Adam15 Mdc15O888398
DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (Met-1) (EC (DNA methyltransferase MmuI) (DNA MTase MmuI) (M.MmuI) (MCMT)Dnmt1 Dnmt Met1 UimP138648
DNA mismatch repair protein Msh2 (MutS protein homolog 2)Msh2P432478
DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (DNA-directed RNA polymerase II 33 kDa polypeptide) (RPB33) (DNA-directed RNA polymerase II subunit C) (RPB31)Polr2c Rpo2-3P977608
E3 ubiquitin-protein ligase SMURF2 (EC (HECT-type E3 ubiquitin transferase SMURF2) (SMAD ubiquitination regulatory factor 2) (SMAD-specific E3 ubiquitin-protein ligase 2)Smurf2A2A5Z68
Elongation factor-like GTPase 1 (Elongation factor Tu GTP-binding domain-containing protein 1) (Elongation factor-like 1) (Protein FAM42A)Efl1 Eftud1Q8C0D58
Endoglin (Cell surface MJ7/18 antigen) (CD antigen CD105)Eng EdgQ639618
Engulfment and cell motility protein 1 (Protein ced-12 homolog)Elmo1Q8BPU78
Enhancer of rudimentary homolog (Mer)ErhP840898
Ephrin type-A receptor 4 (EC (Tyrosine-protein kinase receptor MPK-3) (Tyrosine-protein kinase receptor SEK-1)Epha4 Sek Sek1Q031378
Ephrin type-A receptor 7 (EC (Developmental kinase 1) (mDK-1) (EPH homology kinase 3) (EHK-3) (Embryonic brain kinase) (EBK)Epha7 Ebk Ehk3 Mdk1Q617728
Exocyst complex component 3 (Exocyst complex component Sec6)Exoc3 Sec6l1Q6KAR68
Exocyst complex component 4 (Exocyst complex component Sec8)Exoc4 Sec8 Sec8l1O353828
Exocyst complex component 7 (Exocyst complex component Exo70)Exoc7 Exo70O352508
F-actin-uncapping protein LRRC16A (CARMIL homolog) (Capping protein regulator and myosin 1 linker protein 1) (Capping protein, Arp2/3 and myosin-I linker homolog 1) (Capping protein, Arp2/3 and myosin-I linker protein 1) (CARML1) (Leucine-rich repeat-containing protein 16A)Carmil1 Carmil Lrrc16 Lrrc16aQ6EDY68
FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR)Farp2 Kiaa0793Q91VS88
FH1/FH2 domain-containing protein 1 (Formin homolog overexpressed in spleen 1) (FHOS) (Formin homology 2 domain-containing protein 1)Fhod1 Fhos1Q6P9Q48
Fibulin-5 (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance)Fbln5 DanceQ9WVH98
Frizzled-2 (Fz-2) (mFz2) (Frizzled-10) (Fz-10) (mFz10)Fzd2 Fzd10Q9JIP68
G protein-coupled receptor kinase 5 (EC (G protein-coupled receptor kinase GRK5)Grk5 Gprk5Q8VEB18
GalectinLgals3 mCG_6908Q8C2538
Gamma-tubulin complex component 3 (GCP-3)Tubgcp3 Gcp3P588548
Gem-associated protein 5 (Gemin5)Gemin5Q8BX178
Glucose-induced degradation protein 8 homolog (Two hybrid-associated protein 1 with RanBPM) (Twa1)Gid8Q9D7M18
Glutamate-rich WD repeat-containing protein 1 (Protein A301)Grwd1 A301Q810D68
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10Gng10Q9CXP88
Guanine nucleotide-binding protein subunit alpha-14 (G alpha-14) (G-protein subunit alpha-14)Gna14 Gna-14P306778
H-2 class I histocompatibility antigen, K-W28 alpha chainH2-K1 H2-KP039918
Heterogeneous nuclear ribonucleoprotein A/B (Heterogeneous nuclear ribonucleoprotein A/B, isoform CRA_a) (S1 protein C2)Hnrnpab Hnrpab mCG_6983Q20BD08
Heterogeneous nuclear ribonucleoprotein RHnrnpr HnrprQ8VHM58
High affinity immunoglobulin epsilon receptor subunit gamma (Fc receptor gamma-chain) (FcRgamma) (Fc-epsilon RI-gamma) (IgE Fc receptor subunit gamma) (FceRI gamma)Fcer1g Fce1gP204918
Histidine-rich glycoprotein (Histidine-proline-rich glycoprotein) (HPRG)HrgQ9ESB38
Histone H2B type 3-AHist3h2baQ9D2U98
Hsp70-binding protein 1 (HspBP1) (Heat shock protein-binding protein 1) (Hsp70-interacting protein 1)Hspbp1 HspbpQ99P318
Hypermethylated in cancer 2 protein (Hic-2)Hic2 Kiaa1020Q9JLZ68
Ig alpha chain C region0P018788
Ig heavy chain V region AC38 205.120P063308
Importin subunit alpha-5 (Importin alpha-S1) (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]Kpna1 Rch2Q609608
Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11)Ipo11 Ranbp11Q8K2V68
Inactive rhomboid protein 1 (iRhom1) (Epidermal growth factor receptor-related protein) (Rhomboid family member 1)Rhbdf1 Dist1 Irhom1 Kiaa4242Q6PIX58
Integrin alpha-9Itga9B8JK398
Integrin beta-4 (CD antigen CD104)Itgb4A2A8638
Inter-alpha-trypsin inhibitor heavy chain H1 (ITI heavy chain H1) (ITI-HC1) (Inter-alpha-inhibitor heavy chain 1)Itih1Q617028
Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130)Il6stQ005608
Junctional adhesion molecule C (JAM-C) (JAM-2) (Junctional adhesion molecule 3) (JAM-3)Jam3Q9D8B78
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68)Khdrbs1Q607498
Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8)Klc4 Knsl8Q9DBS58
La-related protein 1 (La ribonucleoprotein domain family member 1)Larp1 Kiaa0731 LarpQ6ZQ588
LanC-like protein 2 (Testis-specific adriamycin sensitivity protein)Lancl2 TaspQ9JJK28
Leucine-rich repeat flightless-interacting protein 1 (LRR FLII-interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP)Lrrfip1 FlapQ3UZ398
Leucine-rich repeat-containing protein 1Lrrc1Q80VQ18
Lon protease homolog, mitochondrial (EC 3.4.21.-) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15)Lonp1 Prss15Q8CGK38
Lumican (Keratan sulfate proteoglycan lumican) (KSPG lumican)Lum Lcn LdcP518858
Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase) (LAL) (EC (Cholesteryl esterase) (Lipase A) (Sterol esterase)Lipa Lip1Q9Z0M58
Lysosomal acid phosphatase (LAP) (EC
Lysozyme C-1 (EC (1,4-beta-N-acetylmuramidase C) (Lysozyme C type P)Lyz1 Lzp-sP178978
Lysyl oxidase homolog 4 (EC 1.4.3.-) (Lysyl oxidase-like protein 4) (Lysyl oxidase-related protein C)Loxl4 LoxcQ924C68
Mammalian ependymin-related protein 1 (MERP-1)Epdr1 Epdr2 Merp1 Merp2Q99M718
Mannose-binding protein C (MBP-C) (Mannan-binding protein) (RA-reactive factor P28A subunit) (RARF/P28A)Mbl2P413178
Matrix remodeling-associated protein 8 (Adipocyte-specific protein 3) (Limitrin)Mxra8 Asp3Q9DBV48
Membrane-associated progesterone receptor component 2Pgrmc2Q80UU98
Metalloproteinase inhibitor 2 (Tissue inhibitor of metalloproteinases 2) (TIMP-2)Timp2 Timp-2P257858
Metalloreductase STEAP3 (EC 1.16.1.-) (Dudulin-2) (Protein nm1054) (Six-transmembrane epithelial antigen of prostate 3) (Tumor suppressor-activated pathway protein 6)Steap3 Tsap6Q8CI598
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