EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
Zinc finger C2HC domain-containing protein 1AZc2hc1a Fam164aQ8BJH15
Zinc finger E-box-binding homeobox 2 (Smad-interacting protein 1) (Zinc finger homeobox protein 1b)Zeb2 Sip1 Zfhx1b Zfx1bQ9R0G75
Zinc finger protein 106 (Zfp-106) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant) (Zinc finger protein 474)Znf106 H3a Sh3bp3 Sirm Zfp106 Znf474O884665
Zinc finger protein 148 (Beta enolase repressor factor 1) (G-rich box-binding protein) (Transcription factor BFCOL1) (Transcription factor ZBP-89) (Zinc finger DNA-binding protein 89)Znf148 Zbp89 Zfp148Q616245
Zinc finger protein 329Znf329 Zfp329Q6GQR85
Zinc finger protein with KRAB and SCAN domains 3 (SCAN-KRAB-zinc finger protein) (Zinc finger protein 306) (Zinc finger protein 307) (Zinc finger protein 47 homolog) (Zf47) (Zfp-47)Zkscan3 Skz1 Zfp306 Zfp307 Zfp47Q91VW95
Zinc finger protein ZFPM1 (Friend of GATA protein 1) (FOG-1) (Friend of GATA 1) (Zinc finger protein multitype 1)Zfpm1 Fog Fog1O356155
26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Mov34 protein) (Proteasome subunit p40)Psmd7 Mov-34 Mov34P265164
26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27)Psmd9Q9CR004
28S ribosomal protein S23, mitochondrial (MRP-S23) (S23mt)Mrps23Q8VE224
28S ribosomal protein S31, mitochondrial (MRP-S31) (S31mt) (Imogen 38)Mrps31 Imogn38Q617334
28S ribosomal protein S33, mitochondrial (MRP-S33) (S33mt) (Ganglioside-induced differentiation-associated-protein 3)Mrps33 Gdap3Q9D2R84
39S ribosomal protein L14, mitochondrial (L14mt) (MRP-L14)Mrpl14Q9D1I64
39S ribosomal protein L15, mitochondrial (L15mt) (MRP-L15)Mrpl15Q9CPR54
39S ribosomal protein L39, mitochondrial (L39mt) (MRP-L39)Mrpl39Q9JKF74
39S ribosomal protein L45, mitochondrial (L45mt) (MRP-L45)Mrpl45Q9D0Q74
40S ribosomal protein S16Rps16P141314
40S ribosomal protein S5 [Cleaved into: 40S ribosomal protein S5, N-terminally processed]Rps5P974614
40S ribosomal protein SA (37 kDa laminin receptor precursor) (37LRP) (37 kDa oncofetal antigen) (37/67 kDa laminin receptor) (LRP/LR) (67 kDa laminin receptor) (67LR) (Laminin receptor 1) (LamR) (Laminin-binding protein precursor p40) (LBP/p40) (OFA/iLRP)Rpsa Lamr1 P40-8P142064
45 kDa calcium-binding protein (Cab45) (Stromal cell-derived factor 4) (SDF-4)Sdf4 Cab45Q611124
5'(3')-deoxyribonucleotidase, mitochondrial (5',3'-nucleotidase, mitochondrial) (EC 3.1.3.-) (Deoxy-5'-nucleotidase 2) (dNT-2)Nt5m Dnt2Q8VCE64
52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0)Prkrir Thap0Q9CUX14
5730403M16Rik protein (Protein Zfp954)Zfp954 5730403M16RikQ7TNU54
60S ribosomal protein L11Rpl11Q9CXW44
60S ribosomal protein L35Rpl35Q6ZWV74
60S ribosomal protein L39Rpl39P628924
60S ribosomal protein L8Rpl8P629184
60S ribosome subunit biogenesis protein NIP7 homolog (PEachy) (kDa93)Nip7Q9CXK84
7-methylguanosine phosphate-specific 5'-nucleotidase (EC 3.1.3.-) (Cytosolic 5'-nucleotidase 3B) (Cytosolic 5'-nucleotidase III-like protein) (cN-III-like protein) (EC Nt5c3lQ3UFY74
A disintegrin and metallopeptidase domain 4 (ADAM4) (MCG1027808) (Protein Adam4)Adam4 mCG_1027808Q8CGQ24
A-kinase anchor protein 9 (AKAP-9) (Protein kinase A-anchoring protein 9) (PRKA9)Akap9 Kiaa0803Q70FJ14
Acetyl-CoA acetyltransferase, mitochondrial (EC (Acetoacetyl-CoA thiolase)Acat1Q8QZT14
Acid-sensing ion channel 3 (ASIC3) (Amiloride-sensitive cation channel 3) (Dorsal root ASIC) (DRASIC)Asic3 Accn3 DrasicQ6X1Y64
Acidic leucine-rich nuclear phosphoprotein 32 family member A (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein) (LANP) (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A)Anp32a Anp32 LanpO353814
Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31)Anp32b Pal31Q9EST54
Acidic leucine-rich nuclear phosphoprotein 32 family member E (Cerebellar postnatal development protein 1) (LANP-like protein) (LANP-L)Anp32e Cpd1P978224
Acyl-Coenzyme A binding domain containing 4 (Acyl-Coenzyme A binding domain containing 4, isoform CRA_a)Acbd4 mCG_19167Q80X944
Adenine phosphoribosyltransferase (APRT) (EC
Adenylate cyclase type 4 (EC (ATP pyrophosphate-lyase 4) (Adenylate cyclase type IV) (Adenylyl cyclase 4)Adcy4Q91WF34
Adenylosuccinate synthetase isozyme 1 (AMPSase 1) (AdSS 1) (EC (Adenylosuccinate synthetase, basic isozyme) (Adenylosuccinate synthetase, muscle isozyme) (M-type adenylosuccinate synthetase) (IMP--aspartate ligase 1)Adssl1 Adss1P286504
Adenylyl cyclase-associated protein 1 (CAP 1)Cap1 CapP401244
ADP-ribosylation factor 6Arf6P623314
ADP-ribosylation factor-like protein 8B (ADP-ribosylation factor-like protein 10C) (Novel small G protein indispensable for equal chromosome segregation 1)Arl8b Arl10c Gie1Q9CQW24
ADP/ATP translocase 1 (ADP,ATP carrier protein 1) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) (Adenine nucleotide translocator 1) (ANT 1) (Solute carrier family 25 member 4) (mANC1)Slc25a4 Anc1 Ant1P489624
AF4/FMR2 family member 1 (Aff1 protein)Aff1A3KMF44
Aflatoxin B1 aldehyde reductase member 2 (EC 1.1.1.n11) (Succinic semialdehyde reductase) (SSA reductase)Akr7a2 Afar Akr7a5Q8CG764
Aldose reductase (AR) (EC (Aldehyde reductase)Akr1b1 Akr1b3 Aldor1 Aldr1P453764
Alpha-1,3/1,6-mannosyltransferase ALG2 (EC (EC (Asparagine-linked glycosylation protein 2 homolog) (GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase) (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) (GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase)Alg2 MNCb-5081Q9DBE84
Alpha-endosulfine (ARPP-19e)EnsaP608404
Alpha-mannosidase 2 (EC (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)Man2a1 Mana2P270464
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 (EC 2.4.99.-) (GalNAc alpha-2,6-sialyltransferase VI) (ST6GalNAc VI) (ST6GalNAcVI) (Sialyltransferase 7F) (SIAT7-F)St6galnac6 Siat7fQ9JM954
Alpha/beta hydrolase domain-containing protein 17C (EC 3.-.-.-)Abhd17cQ8VCV14
AN1-type zinc finger protein 2B (Arsenite-inducible RNA-associated protein-like protein) (AIRAP-like protein)Zfand2b AiraplQ91X584
AN1-type zinc finger protein 3 (Testis-expressed sequence 27)Zfand3 Tex27Q497H04
Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11)Anapc11Q9CPX94
Anaphase-promoting complex subunit 15 (APC15)Anapc15P600074
Anionic trypsin-2 (EC (Anionic trypsin II) (Pretrypsinogen II) (Serine protease 2)Prss2 Try2P071464
Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein)Ankrd17 Foe Gtar Kiaa0697Q99NH04
Ankyrin repeat domain-containing protein 32 (BRCT domain-containing protein 1)Ankrd32 Brctd1Q8R3P94
Ankyrin repeat domain-containing protein 39Ankrd39Q9D2X04
Ankyrin repeat domain-containing protein 54 (Lyn-interacting ankyrin repeat protein)Ankrd54 LiarQ91WK74
Annexin A5 (Anchorin CII) (Annexin V) (Annexin-5) (Calphobindin I) (CBP-I) (Endonexin II) (Lipocortin V) (Placental anticoagulant protein 4) (PP4) (Placental anticoagulant protein I) (PAP-I) (Thromboplastin inhibitor) (Vascular anticoagulant-alpha) (VAC-alpha)Anxa5 Anx5P480364
AP-1 complex subunit beta-1 (Adapter-related protein complex 1 subunit beta-1) (Adaptor protein complex AP-1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit)Ap1b1 Adtb1O356434
AP-2 complex subunit beta (AP105B) (Adapter-related protein complex 2 subunit beta) (Adaptor protein complex AP-2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit)Ap2b1 Clapb1Q9DBG34
Apolipoprotein B receptor (Apolipoprotein B-100 receptor) (Apolipoprotein B48 receptor) (apoB-48R)Apobr Apob48rQ8VBT64
Apoptosis inhibitor 5 (API-5) (AAC-11)Api5O358414
Apoptosis-resistant E3 ubiquitin protein ligase 1 (EC 6.3.2.-)Arel1 Kiaa0317Q8CHG54
Aquaporin-1 (AQP-1) (Aquaporin-CHIP) (Delayed early response protein 2) (DER2) (Water channel protein for red blood cells and kidney proximal tubule)Aqp1Q020134
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (AGAP-1) (Centaurin-gamma-2) (Cnt-g2)Agap1 Centg2 Kiaa1099Q8BXK84
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 (Centaurin-delta-3) (Cnt-d3) (Dual specificity Rho- and Arf-GTPase-activating protein 1)Arap3 Centd3 Drag1 Kiaa4097Q8R5G74
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (Development and differentiation-enhancing factor 2) (Paxillin-associated protein with ARF GAP activity 3) (PAG3) (Pyk2 C-terminus-associated protein) (PAP)Asap2 Ddef2 Gm1523 Gm592Q7SIG64
Armadillo repeat-containing X-linked protein 3Armcx3Q8BHS64
Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1-beta) (HIF-1-beta) (HIF1-beta)ArntP537624
Arylsulfatase J (ASJ) (EC 3.1.6.-)ArsjQ8BM894
Asparagine synthetase domain-containing protein 1Asnsd1Q8BFS94
ATP synthase F(0) complex subunit C2, mitochondrial (ATP synthase lipid-binding protein) (ATP synthase proteolipid P2) (ATPase protein 9) (ATPase subunit c)Atp5g2P563834
ATP synthase F(0) complex subunit C3, mitochondrial (ATP synthase lipid-binding protein) (ATP synthase proteolipid P3) (ATPase protein 9) (ATPase subunit c)Atp5g3P563844
ATP synthase subunit O, mitochondrial (Oligomycin sensitivity conferral protein) (OSCP)Atp5o D12Wsu28eQ9DB204
ATP synthase subunit s, mitochondrial (ATP synthase-coupling factor B) (Mitochondrial ATP synthase regulatory component factor B)Atp5s AtpwQ9CRA74
ATP-binding cassette sub-family C member 9 (Sulfonylurea receptor 2)Abcc9 Sur2P701704
ATP-binding cassette sub-family F member 2Abcf2Q99LE64
ATP-dependent RNA helicase DDX1 (EC (DEAD box protein 1)Ddx1Q91VR54
ATP-dependent RNA helicase DDX42 (EC (DEAD box protein 42)Ddx42Q810A74
ATP-dependent RNA helicase DDX51 (EC (DEAD box protein 51)Ddx51Q6P9R14
ATPase, class I, type 8B, member 3 (Protein Atp8b3) (SAPLT)Atp8b3Q6UQ174
Atrial natriuretic peptide receptor 3 (Atrial natriuretic peptide clearance receptor) (Atrial natriuretic peptide receptor type C) (ANP-C) (ANPR-C) (NPR-C) (EF-2)Npr3P701804
B-cell CLL/lymphoma 7 protein family member BBcl7bQ921K94
B-cell lymphoma 6 protein homologBcl6 Bcl-6P411834
Band 4.1-like protein 5Epb41l5 Epb4.1l5 Kiaa1548Q8BGS14
Bardet-Biedl syndrome 4 protein homologBbs4Q8C1Z74
Battenin (Protein CLN3)Cln3Q611244
Bcl-2-associated transcription factor 1 (Btf)Bclaf1 Btf Kiaa0164Q8K0194
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2Bnip2 Nip2lO549404
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein)Becn1O885974
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (EC (Core 2-branching enzyme) (Core2-GlcNAc-transferase) (C2GNT)Gcnt1Q093244
Beta-1,3-glucuronyltransferase 1 (Glucuronosyltransferase P) (Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1)B3gat1Q6PIG84
Beta-1,4-galactosyltransferase 3 (Beta-1,4-GalTase 3) (Beta4Gal-T3) (b4Gal-T3) (EC 2.4.1.-) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3) [Includes: N-acetyllactosamine synthase (EC (Nal synthase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)]B4galt3Q91YY24
Beta-lactamase-like protein 2 (EC 3.-.-.-)Lactb2Q99KR34
Bifunctional apoptosis regulatorBfarQ8R0794
Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC (Glutamyl-tRNA synthetase) (GluRS); Proline--tRNA ligase (EC (Prolyl-tRNA synthetase) (ProRS)]Eprs QprsQ8CGC74
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