EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
Bifunctional protein NCOAT (Meningioma-expressed antigen 5) (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) [Includes: Protein O-GlcNAcase (EC (Glycoside hydrolase O-GlcNAcase) (Hexosaminidase C) (N-acetyl-beta-D-glucosaminidase) (N-acetyl-beta-glucosaminidase) (O-GlcNAcase) (OGA); Histone acetyltransferase (HAT) (EC]Mgea5 Hexc Kiaa0679Q9EQQ94
Biogenesis of lysosome-related organelles complex 1 subunit 5 (BLOC-1 subunit 5) (Protein Muted homolog)Bloc1s5 Mu MutedQ8R0154
Brain-specific angiogenesis inhibitor 2Bai2Q8CGM14
BRISC complex subunit Abro1 (Abraxas brother protein 1) (Protein FAM175B)Fam175b Abro1 Kiaa0157Q3TCJ14
Bromodomain-containing protein 9Brd9Q3UQU04
C-Jun-amino-terminal kinase-interacting protein 2 (JIP-2) (JNK-interacting protein 2) (Islet-brain-2) (IB-2) (JNK MAP kinase scaffold protein 2) (Mitogen-activated protein kinase 8-interacting protein 2)Mapk8ip2 Ib2 Jip2Q9ERE94
C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9)Spag9 Jip4 Jsap2 Kiaa0516 Mapk8ip4Q58A654
C-type lectin domain family 2 member EClec2eH7BWZ44
C-X-C chemokine receptor type 5 (CXC-R5) (CXCR-5) (Burkitt lymphoma receptor 1 homolog) (CD antigen CD185)Cxcr5 Blr1 Gpcr6Q046834
CAAX box 1 homolog A (Human) (CAAX box 1 homolog B (Human)) (MCG1026783) (Protein Cxx1a) (Protein Cxx1b)Cxx1b Cxx1a mCG_1026783Q9D1F04
Calcineurin subunit B type 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1)Ppp3r1 CnbQ638104
Calcium-binding protein 39-like (MO25beta) (Mo25-like protein)Cab39lQ9DB164
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Calmodulin-stimulated cyclic nucleotide phosphodiesterase PDE1A9)Pde1aQ5I7S84
Calreticulin-3 (Calreticulin-2) (Calsperin)Calr3 Crt2Q9D9Q64
cAMP-regulated phosphoprotein 19 (ARPP-19)Arpp19P562124
Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC Ck1g2Q8BVP54
Cathepsin Z (EC
CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2)Cnot2Q8C5L34
CCR4-NOT transcription complex subunit 6 (EC (CCR4 carbon catabolite repression 4-like) (Carbon catabolite repressor protein 4 homolog) (Cytoplasmic deadenylase)Cnot6 Ccr4 Kiaa1194Q8K3P54
CDGSH iron-sulfur domain-containing protein 1 (MitoNEET)Cisd1 D10Ertd214e Zcd1Q91WS04
CDK5 and ABL1 enzyme substrate 1 (Interactor with CDK3 1) (Ik3-1)Cables1 CablesQ9ESJ14
Cell adhesion molecule 2 (Immunoglobulin superfamily member 4D) (IgSF4D) (Nectin-like protein 3) (NECL-3) (Synaptic cell adhesion molecule 2) (SynCAM 2)Cadm2 Igsf4d Necl3Q8BLQ94
Cell cycle control protein 50A (Transmembrane protein 30A)Tmem30a Cdc50a D9Wsu20eQ8VEK04
Cell division cycle protein 27 homologCdc27A2A6Q54
Cellular nucleic acid-binding protein (CNBP) (Zinc finger protein 9)Cnbp Cnbp1 Znf9P539964
Centromere protein P (CENP-P)CenppQ9CZ924
Centrosomal protein of 120 kDa (Cep120) (Coiled-coil domain-containing protein 100)Cep120 Ccdc100Q7TSG14
Ceramide synthase 5 (CerS5) (EC (LAG1 longevity assurance homolog 5) (Translocating chain-associating membrane protein homolog 4) (TRAM homolog 4)Cers5 Lass5 Trh4Q9D6K94
CGG triplet repeat-binding protein 1 (CGG-binding protein 1) (20 kDa CGG-binding protein) (p20-CGGBP DNA-binding protein)Cggbp1Q8BHG94
Chitinase-3-like protein 3 (ECF-L) (Eosinophil chemotactic cytokine) (Secreted protein Ym1)Chi3l3 Ym1O357444
Cholinephosphotransferase 1 (mCHPT1) (EC (Diabetic nephropathy-associated gene transcript 1) (Diacylglycerol cholinephosphotransferase 1)Chpt1 Cpt1 Dn4Q8C0254
Chromatin target of PRMT1 protein (Friend of PRMT1 protein) (Small arginine- and glycine-rich protein) (SRAG)Chtop Fop MNCb-1706Q9CY574
Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein)Cbx1 CbxP839174
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC
CKLF-like MARVEL transmembrane domain-containing protein 7 (Chemokine-like factor superfamily member 7) (LNV)Cmtm7 Cklfsf7 LnvQ9ESD64
Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (Clipper homolog) (Clipper/CPSF 30K)Cpsf4 Cpsf30Q8BQZ54
Cleavage and polyadenylation specificity factor subunit 5 (Nucleoside diphosphate-linked moiety X motif 21) (Nudix motif 21)Nudt21 Cpsf5Q9CQF34
CLIP-associating protein 2Clasp2E9Q8N54
Coatomer subunit zeta-1 (Zeta-1-coat protein) (Zeta-1 COP)Copz1 CopzP619244
Coiled-coil domain containing 32 (Uncharacterized protein C15orf57 homolog)Ccdc32 Gm631 mCG_6524Q3UHY74
Coiled-coil domain-containing protein 117Ccdc117Q6PB514
Coiled-coil domain-containing protein 12Ccdc12Q8R3444
Coiled-coil domain-containing protein 127Ccdc127Q3TC334
Coiled-coil domain-containing protein 93Ccdc93Q7TQK54
Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 (28S ribosomal protein S37, mitochondrial) (MRP-S37)Chchd1 Mrps37Q9CQA64
Coiled-coil-helix-coiled-coil-helix domain-containing protein 7Chchd7Q8K2Q54
Collagen alpha-1(III) chainCol3a1P081214
Collagen alpha-1(IV) chain [Cleaved into: Arresten]Col4a1P024634
Collagen alpha-4(IV) chainCol4a4Q9QZR94
COMM domain-containing protein 4Commd4Q9CQ024
Complement factor H (Protein beta-1-H)Cfh Hf1P069094
Conserved oligomeric Golgi complex subunit 2 (COG complex subunit 2) (Component of oligomeric Golgi complex 2) (Low density lipoprotein receptor defect C-complementing protein)Cog2 LdlcQ921L54
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)Cops2 Csn2 Trip15P612024
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y)H2afyQ9QZQ84
Corepressor interacting with RBPJ 1 (CBF1-interacting corepressor)Cir1 CirQ9DA194
CTD small phosphatase-like protein (CTDSP-like) (EC (Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3) (NIF-like protein) (Nuclear LIM interactor-interacting factor 1) (NLI-interacting factor 1) (Small C-terminal domain phosphatase 3) (SCP3) (Small CTD phosphatase 3)Ctdspl Nif1 NiflP584654
CUGBP Elav-like family member 2 (CELF-2) (Bruno-like protein 3) (CUG triplet repeat RNA-binding protein 2) (CUG-BP2) (CUG-BP- and ETR-3-like factor 2) (ELAV-type RNA-binding protein 3) (ETR-3) (mETR-3) (Neuroblastoma apoptosis-related RNA-binding protein) (mNapor) (RNA-binding protein BRUNOL-3)Celf2 Cugbp2 NaporQ9Z0H44
Cullin-5 (CUL-5)Cul5Q9D5V54
Cyclic AMP-dependent transcription factor ATF-1 (cAMP-dependent transcription factor ATF-1) (Activating transcription factor 1) (TCR-ATF1)Atf1P812694
Cyclic AMP-responsive element-binding protein 3-like protein 2 (cAMP-responsive element-binding protein 3-like protein 2) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 2]Creb3l2 Bbf2h7Q8BH524
Cyclin-dependent kinase 11B (Cell division cycle 2-like protein kinase 1) (Cell division protein kinase 11) (Cyclin-dependent kinase 11) (EC (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1)Cdk11b Cdc2l1 Cdk11P247884
Cyclin-dependent kinase 16 (EC (CRK5) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)Cdk16 Crk5 Pctaire1 Pctk1Q047354
Cyclin-dependent kinase 20 (EC (CDK-activating kinase p42) (CAK-kinase p42) (CDK-related protein kinase PNQLARE) (Cell cycle-related kinase) (Cell division protein kinase 20) (Cyclin-dependent protein kinase H) (Cyclin-kinase-activating kinase p42)Cdk20 Ccrk CdchQ9JHU34
Cyclin-dependent kinase 6 (EC (CR2 protein kinase) (CRK2) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)Cdk6 Cdkn6 Crk2Q642614
Cysteine and glycine-rich protein 1 (Cysteine-rich protein 1) (CRP) (CRP1)Csrp1 Crp1 CsrpP973154
Cysteine and glycine-rich protein 2 (Cysteine-rich protein 2) (CRP2) (Double LIM protein 1) (DLP-1)Csrp2 Dlp1P973144
Cysteine--tRNA ligase, cytoplasmic (EC (Cysteinyl-tRNA synthetase) (CysRS)CarsQ9ER724
Cysteine-rich motor neuron 1 protein (CRIM-1)Crim1Q9JLL04
Cysteine-rich protein 2 (CRP-2) (Heart LIM protein)Crip2 Crp2 HlpQ9DCT84
Cysteine-rich protein 2-binding protein (CSRP2-binding protein) (ADA2A-containing complex subunit 2) (ATAC2) (CRP2-binding partner) (CRP2BP)Csrp2bpQ8CID04
Cytochrome b-c1 complex subunit 6, mitochondrial (Complex III subunit 6) (Complex III subunit VIII) (Cytochrome c1 non-heme 11 kDa protein) (Mitochondrial hinge protein) (Ubiquinol-cytochrome c reductase complex 11 kDa protein)UqcrhP990284
Cytochrome c oxidase assembly factor 5Coa5Q99M074
Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (CLM1) (SEC7 homolog A) (mSec7-1)Cyth1 Pscd1Q9QX114
Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic)Dync1li2 Dncli2 Dnclic2Q6PDL04
Cytoplasmic tRNA 2-thiolation protein 1 (EC 2.7.7.-) (ATP-binding domain-containing protein 3) (Cytoplasmic tRNA adenylyltransferase 1)Ctu1 Atpbd3 Ncs6Q99J104
Cytoplasmic tyrosine-protein kinase BMX (EC (Bone marrow tyrosine kinase gene in chromosome X protein homolog)BmxP975044
Cytosolic purine 5'-nucleotidase (EC (Cytosolic 5'-nucleotidase II)Nt5c2Q3V1L44
DCC-interacting protein 13-alpha (Dip13-alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1)Appl1 Dip13a Kiaa1428Q8K3H04
DDB1- and CUL4-associated factor 12 (WD repeat-containing protein 40A)Dcaf12 Kiaa1892 Wdr40aQ8BGZ34
Death ligand signal enhancerKiaa0141 DeleQ9DCV64
Death-associated protein 1 (DAP-1)DapQ91XC84
Decapping and exoribonuclease protein (DXO) (EC 3.1.13.-) (EC 3.6.1.-) (Dom-3 homolog Z)Dom3z Ng6O703484
DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1)Dennd5a Rab6ip1Q6PAL84
DENN domain-containing protein 5B (Rab6IP1-like protein)Dennd5bA2RSQ04
Deoxycytidine kinase (dCK) (EC
Differentially expressed in FDCP 8 (DEF-8)Def8 D8Ertd713eQ99J784
Dihydrolipoyl dehydrogenase, mitochondrial (EC (Dihydrolipoamide dehydrogenase)DldO087494
Dihydropyrimidinase-like 4 (Dihydropyrimidinase-related protein 4)Dpysl4Q3TMU84
Diphosphoinositol polyphosphate phosphohydrolase 2 (DIPP-2) (EC (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 4) (Nudix motif 4)Nudt4 Dipp2Q8R2U64
DNA primase small subunit (EC 2.7.7.-) (DNA primase 49 kDa subunit) (p49)Prim1P206644
DNA-(apurinic or apyrimidinic site) lyase (EC 3.1.-.-) (EC (APEX nuclease) (APEN) (Apurinic-apyrimidinic endonuclease 1) (AP endonuclease 1) (REF-1) (Redox factor-1) [Cleaved into: DNA-(apurinic or apyrimidinic site) lyase, mitochondrial]Apex1 Ape Apex Ref1P283524
DNA-binding protein inhibitor ID-4 (Inhibitor of DNA binding 4)Id4 Id-4 Idb4P411394
DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor of 58 kDa) (Protein kinase inhibitor p58)Dnajc3 P58ipkQ91YW34
DNL-type zinc finger protein (Hsp70-escort protein 1) (HEP1) (mtHsp70-escort protein)Dnlz D2Bwg1335eQ9D1134
Dolichyl-phosphate beta-glucosyltransferase (DolP-glucosyltransferase) (EC (Asparagine-linked glycosylation protein 5 homolog)Alg5Q9DB254
Double-strand-break repair protein rad21 homolog (Pokeweed agglutinin-binding protein 29) (PW29) (SCC1 homolog)Rad21 Hr21Q615504
Dr1-associated corepressor (Dr1-associated protein 1) (Negative cofactor 2-alpha) (NC2-alpha)Drap1Q9D6N54
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