EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Flagellar hook-basal body complex protein FliEfliE HP_1557P677084
Flagellar L-ring protein (Basal body L-ring protein)flgH BE932_29605 SY51_05960A0A061YHE64
Flagellar M-ring proteinfliF PA1101Q514634
FlagellinSmlt2306B2FQU74
Flagellin B (Flagellin N)flaB HP_0115Q079114
Flagellin B homolog (Fla)HP_0295O250684
Foldase protein PrsA (EC 5.2.1.8)prsA LMRG_00896A0A0H3GC414
Formate acetyltransferase 3 (EC 2.3.1.54)pflF spr0232Q8DRB94
Formate dehydrogenase-O, major subunitfdnG PA4812Q14T724
Fructokinase (EC 2.7.1.4)BE932_25590 SY51_02075A0A066T5J44
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13)NGO_0034Q5FAI44
Fumarate hydratase class II 1 (Fumarase C 1) (EC 4.2.1.2) (Aerobic fumarase 1) (Iron-independent fumarase 1)fumC1 PA0854Q9I5874
Fumarate hydratase class II 2 (Fumarase C 2) (EC 4.2.1.2) (Aerobic fumarase 2) (Iron-independent fumarase 2)fumC2 PA4470Q514044
Fumarate reductase flavoprotein subunitLMRG_00046A0A0H3GDC34
Fumarate reductase flavoprotein subunit (EC 1.3.5.4)frdA b4154 JW4115P003634
Galactokinase (EC 2.7.1.6) (Galactose kinase)galK A4T40_07475 BK334_19595 BMT97_08250 BXT93_19270 ECONIH1_04335 MS6198_08290A0A023LD424
GDSL family lipaseNGO_1323Q5F7634
Glucanase (EC 3.2.1.-)BE932_16710 SY51_20170A0A061KA724
Glucokinase (EC 2.7.1.2) (Glucose kinase)glk AKG99_12105 AML35_22215 BHF46_01260 BK400_08340 JD73_18410 UN91_13705A0A066QBR94
Glucose dehydrogenasegcd PA2290Q9I1I54
Glutamate dehydrogenasegdhA NMB1710Q9JY714
Glutamate dehydrogenaseNGO_1358Q5F7314
Glutamate-1-semialdehyde 2,1-aminomutase (GSA) (EC 5.4.3.8) (Glutamate-1-semialdehyde aminotransferase) (GSA-AT)hemL NGO0040Q5FAH94
Glutaminase (EC 3.5.1.2)glsA BY96_20930A0A027TLF24
Glutamine ABC transporterLMRG_02270A0A0H3GES44
Glutamine ABC transporter ATP-binding proteinNGO_2013Q5F5B64
Glutamine synthetase (EC 6.3.1.2)NGO_1600Q5F6F94
Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate--ammonia ligase) (Glutamine synthetase I beta) (GSI beta)glnA b3870 JW3841P0A9C54
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase) (GFAT) (Glucosamine-6-phosphate synthase) (Hexosephosphate aminotransferase) (L-glutamine--D-fructose-6-phosphate amidotransferase)glmS NGO2045Q5F5844
Glutamyl-tRNA(Gln) amidotransferase subunit A (Glu-ADT subunit A) (EC 6.3.5.7)gatA NGO0662Q5F8U84
Glutathione peroxidaseNGO_0926Q5F8654
Glutathione S-transferase (Putative glutathione S-transferase)yfcF A4T50_04560 AA102_03450 ACN77_21960 ACU90_07120 AM270_05800 APT94_13450 BE932_09115 BE949_08755 BE963_27315 BIQ85_13145 BK383_00160 BK400_07960 BMT53_24525 BMT91_07865 BUE82_07025 ERS085374_00271 PU06_12845 SY51_13155A0A023LIH44
Glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.-)NGO_1931Q5F5J34
Glycerol dehydrogenasegldA EC958_4432W9AN434
Glycerol-3-phosphate dehydrogenase (EC 1.1.5.3)glpD PA3584P521114
Glycerophosphodiester phosphodiesterase (EC 3.1.4.46) (Glycerophosphoryl diester phosphodiesterase)glpQ BE932_08805 SY51_12850A0A066T4F84
Glycerophosphoryl diester phosphodiesterase, periplasmicglpQ PA0347Q9I6E64
Glycine dehydrogenase (decarboxylating) (EC 1.4.4.2) (Glycine cleavage system P-protein) (Glycine decarboxylase) (Glycine dehydrogenase (aminomethyl-transferring))gcvP NGO1325Q5F7614
Glycine--tRNA ligase alpha subunit (EC 6.1.1.14) (Glycyl-tRNA synthetase alpha subunit) (GlyRS)glyQ NGO2153Q5F4Y84
Glycine--tRNA ligase alpha subunit (EC 6.1.1.14) (Glycyl-tRNA synthetase alpha subunit) (GlyRS)glyQ CKO_05016A8ARE64
Glycine--tRNA ligase beta subunit (EC 6.1.1.14) (Glycyl-tRNA synthetase beta subunit) (GlyRS)glyS NGO2154Q5F4Y74
Glycine--tRNA ligase beta subunit (EC 6.1.1.14) (Glycyl-tRNA synthetase beta subunit) (GlyRS)glyS PA0008Q9I7B84
Glycosyl transferase family 1NGO_2072Q5F5644
GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (Glutamine amidotransferase)guaA NGO2164Q5F4X94
GTP-binding proteinNGO_0803Q5F8H04
GTPase Der (GTP-binding protein EngA)der engA NGO0424O874074
GTPase HflX (GTP-binding protein HflX)hflX AML07_13375 APZ14_20380 FORC28_5497A0A0F3WC184
GTPase Obg (EC 3.6.5.-) (GTP-binding protein Obg)obg UMNK88_3944A0A0E0U5074
Helix-turn-helix domain-containing protein (Plasmid replication protein) (Putative replication protein) (RepA) (RepA plasmid replication protein) (RepA protein)repA A9R57_26395 BET08_29850 BK251_29070 BK292_26605 BK334_27740 BK373_09775 BK383_13625 BMT61_25985 BMT91_26435 EL75_p7001O071024
Heme uptake outer membrane receptor HasRhasR PA3408Q9HYJ74
HemolysinNGO_1985Q5F5E44
Histidine--tRNA ligase (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)hisS NGO0426Q5F9G84
Histidinol dehydrogenase (HDH) (EC 1.1.1.23)hisD BE932_07560 SY51_11740A0A061K4614
Histidinol-phosphate aminotransferase (EC 2.6.1.9) (Imidazole acetol-phosphate transaminase)hisC NGO1241Q5F7D74
HIT family hydrolaseNGO_0184Q5FA484
Homoserine dehydrogenase (EC 1.1.1.3)NGO_0779Q5F8J44
HTH-type transcriptional activator AllS (LysR family transcriptional regulator)allS_4 A4T40_21205 BK334_09970 ECONIH1_18440 ERS085366_04458 MS6198_35900A0A0A1A9124
HU, DNA-binding transcriptional regulator, alpha subunithupA CE10_4680A0A0E0VE474
Hydrolase (Sugar phosphatase) (EC 3.6.1.-) (Sugar/pyridoxal phosphate phosphatase YigL)cof_2 BE932_18410 BK373_14370 ERS085406_03377 MJ49_10575 SY51_21765E2QHZ94
Imidazole glycerol phosphate synthase subunit HisF (EC 4.1.3.-) (IGP synthase cyclase subunit) (IGP synthase subunit HisF) (ImGP synthase subunit HisF) (IGPS subunit HisF)hisF NGO0211Q5FA234
Imidazoleglycerol-phosphate dehydratase (IGPD) (EC 4.2.1.19)hisB NGO1242Q5F7D64
Imidazoleglycerol-phosphate dehydratase (IGPD) (EC 4.2.1.19)hisB PA5143Q9HU414
Indole-3-glycerol phosphate synthase (IGPS) (EC 4.1.1.48)trpC NGO1721Q5F6454
Inhibitor of vertebrate C-lysozymeivy ECED1_0254B7MQ574
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205)guaB NGO_0799Q5F8H44
Inositol-1-monophosphatase (I-1-Pase) (IMPase) (Inositol-1-phosphatase) (EC 3.1.3.25)suhB Z3800 ECs3399P0ADG64
Integration host factor subunit beta (IHF-beta)ihfB himD NGO_0603Q5F9064
Internalin BLMRG_00127A0A0H3G9Y94
Invasion associated secreted endopeptidaseLMRG_00264A0A0H3GDY44
Ion channel protein Tsx (Nucleoside-specific channel-forming protein Tsx) (Nucleoside-specific channel-forming protein tsx)tsx A4T50_25945 APU18_24610 BE932_25670 BMT49_03340 ERS085406_02207 SY51_02155 WM48_02370E2QGF54
Iron ABC transporter substrate-binding proteinNGO_0217Q5FA174
Iron ABC transporter substrate-binding proteinNGO_2092Q5F5444
Iron complex transport system substrate-binding proteinLMRG_00223A0A0H3G9K04
Iron complex transport system substrate-binding proteinLMRG_01817A0A0H3GES24
Iron-sulfur cluster carrier proteinNGO_0056Q5FAG64
Isocitrate lyase (ICL) (EC 4.1.3.1) (Isocitrase) (Isocitratase)aceA icl b4015 JW3975P0A9G64
Isoleucine--tRNA ligase (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS)ileS PA4560Q9HVM44
Isoleucine--tRNA ligase (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS)ileS NGO0069Q5FAF54
Kelch motif/HYR domain proteinMXAN_6245Q1CYZ94
KetodeoxygluconokinaseBE932_16675 SY51_20145A0A066T2734
Ketol-acid reductoisomerase (NADP(+)) (KARI) (EC 1.1.1.86) (Acetohydroxy-acid isomeroreductase) (AHIR) (Alpha-keto-beta-hydroxylacyl reductoisomerase) (Ketol-acid reductoisomerase type 1) (Ketol-acid reductoisomerase type I)ilvC NGO1233Q5F7E54
Ketol-acid reductoisomerase (NADP(+)) (KARI) (EC 1.1.1.86) (Acetohydroxy-acid isomeroreductase) (AHIR) (Alpha-keto-beta-hydroxylacyl reductoisomerase) (Ketol-acid reductoisomerase type 1) (Ketol-acid reductoisomerase type I)ilvC spr0403Q8DR034
L,D-transpeptidase catalytic domain proteinNGO_1484Q5F6R54
Lactate dehydrogenase (EC 1.1.1.28)NGO_1336Q5F7514
Lactate dehydrogenase (EC 1.1.2.3)lldD NGO_0639Q5F8X14
Large-conductance mechanosensitive channelmscL ECS88_3678B7MCQ64
LemA proteinLMRG_02061A0A0H3GF244
Leucine ABC transporter substrate-binding proteinBY96_07660A0A027U1894
Leucine--tRNA ligase (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)leuS NGO0006Q5FAJ34
Ligand-gated channelNGO_1495Q5F6Q44
Ligand-gated channelNGO_1205Q5F7H34
Lipid A export ATP-binding/permease protein MsbA (EC 3.6.3.-)msbA PA4997Q9HUG84
Lipopolysaccharide export system protein LptAyhbN lptA AC789_1c35700A0A090J8984
Lipoproteinmlp NMB1898Q9JXT14
LipoproteinNGO_1043Q5F7X24
LipoproteinNGO_2139Q5F5014
LipoproteinNGO_0690Q5F8S04
LipoproteinBY96_21235A0A027TKH14
LipoproteinLMRG_01831A0A0H3GIV04
Lipoprotein (Putative lipoprotein)ACN77_12895 APT94_18490 AUS26_02690 BE949_12180 BHF46_13505 BIQ85_05765 BK248_04015 BMT94_03935 BV389_08140 ERS150876_00279 GJ12_05575 PU06_12170 RG28_18715 SM09_01799 UN91_21435A0A066QZP84
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