EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-)GAPDH GAPD CDABP0047 OK/SW-cl.12P04406410
Alpha-enolase (EC (2-phospho-D-glycerate hydro-lyase) (C-myc promoter-binding protein) (Enolase 1) (MBP-1) (MPB-1) (Non-neural enolase) (NNE) (Phosphopyruvate hydratase) (Plasminogen-binding protein)ENO1 ENO1L1 MBPB1 MPB1P06733402
Pyruvate kinase PKM (EC (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (p58)PKM OIP3 PK2 PK3 PKM2P14618394
Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)HSPA8 HSC70 HSP73 HSPA10P11142392
Annexin A2 (Annexin II) (Annexin-2) (Calpactin I heavy chain) (Calpactin-1 heavy chain) (Chromobindin-8) (Lipocortin II) (Placental anticoagulant protein IV) (PAP-IV) (Protein I) (p36)ANXA2 ANX2 ANX2L4 CAL1H LPC2DP07355380
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)YWHAZP63104376
L-lactate dehydrogenase A chain (LDH-A) (EC (Cell proliferation-inducing gene 19 protein) (LDH muscle subunit) (LDH-M) (Renal carcinoma antigen NY-REN-59)LDHA PIG19P00338370
14-3-3 protein epsilon (14-3-3E)YWHAEP62258366
L-lactate dehydrogenase B chain (LDH-B) (EC (LDH heart subunit) (LDH-H) (Renal carcinoma antigen NY-REN-46)LDHBP07195363
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)PFN1P07737361
Annexin A5 (Anchorin CII) (Annexin V) (Annexin-5) (Calphobindin I) (CBP-I) (Endonexin II) (Lipocortin V) (Placental anticoagulant protein 4) (PP4) (Placental anticoagulant protein I) (PAP-I) (Thromboplastin inhibitor) (Vascular anticoagulant-alpha) (VAC-alpha)ANXA5 ANX5 ENX2 PP4P08758359
Fructose-bisphosphate aldolase A (EC (Lung cancer antigen NY-LU-1) (Muscle-type aldolase)ALDOA ALDAP04075359
Peroxiredoxin-1 (EC (Natural killer cell-enhancing factor A) (NKEF-A) (Proliferation-associated gene protein) (PAG) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2)PRDX1 PAGA PAGB TDPX2Q06830356
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]PPIA CYPAP62937353
Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform)CFL1 CFLP23528351
Phosphoglycerate kinase 1 (EC (Cell migration-inducing gene 10 protein) (Primer recognition protein 2) (PRP 2)PGK1 PGKA MIG10 OK/SW-cl.110P00558349
Actin, cytoplasmic 1 (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]ACTBP60709348
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)CLTC CLH17 CLTCL2 KIAA0034Q00610347
Moesin (Membrane-organizing extension spike protein)MSNP26038347
Triosephosphate isomerase (TIM) (EC (Triose-phosphate isomerase)TPI1 TPIP60174347
Heat shock protein HSP 90-alpha (Heat shock 86 kDa) (HSP 86) (HSP86) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)HSP90AA1 HSP90A HSPC1 HSPCAP07900344
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84)HSP90AB1 HSP90B HSPC2 HSPCBP08238343
Keratin, type II cytoskeletal 1 (67 kDa cytokeratin) (Cytokeratin-1) (CK-1) (Hair alpha protein) (Keratin-1) (K1) (Type-II keratin Kb1)KRT1 KRTAP04264339
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]YWHABP31946338
Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (ALG-2-interacting protein X) (Hp95)PDCD6IP AIP1 ALIX KIAA1375Q8WUM4337
Chloride intracellular channel protein 1 (Chloride channel ABP) (Nuclear chloride ion channel 27) (NCC27) (Regulatory nuclear chloride ion channel protein) (hRNCC)CLIC1 G6 NCC27O00299333
Galectin-3-binding protein (Basement membrane autoantigen p105) (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (MAC2BP) (Mac-2 BP) (Tumor-associated antigen 90K)LGALS3BP M2BPQ08380333
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)HSPA5 GRP78P11021332
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]FN1 FNP02751332
Myosin-9 (Cellular myosin heavy chain, type A) (Myosin heavy chain 9) (Myosin heavy chain, non-muscle IIa) (Non-muscle myosin heavy chain A) (NMMHC-A) (Non-muscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA)MYH9P35579332
Tubulin beta chain (Tubulin beta-5 chain)TUBB TUBB5 OK/SW-cl.56P07437332
Elongation factor 1-alpha 1 (EF-1-alpha-1) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7)EEF1A1 EEF1A EF1A LENG7P68104331
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)VCPP55072331
Elongation factor 2 (EF-2)EEF2 EF2P13639326
Ezrin (Cytovillin) (Villin-2) (p81)EZR VIL2P15311324
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)YWHAQP27348322
Sodium/potassium-transporting ATPase subunit alpha-1 (Na(+)/K(+) ATPase alpha-1 subunit) (EC (Sodium pump subunit alpha-1)ATP1A1P05023322
Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)KRT2 KRT2A KRT2EP35908321
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]YWHAGP61981319
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)ITGB1 FNRB MDF2 MSK12P05556314
Ras-related protein Rab-7aRAB7A RAB7P51149314
Syntenin-1 (Melanoma differentiation-associated protein 9) (MDA-9) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18) (Scaffold protein Pbp1) (Syndecan-binding protein 1)SDCBP MDA9 SYCLO00560314
Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)KRT9P35527310
4F2 cell-surface antigen heavy chain (4F2hc) (4F2 heavy chain antigen) (Lymphocyte activation antigen 4F2 large subunit) (Solute carrier family 3 member 2) (CD antigen CD98)SLC3A2 MDU1P08195309
Fatty acid synthase (EC [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC; [Acyl-carrier-protein] S-malonyltransferase (EC; 3-oxoacyl-[acyl-carrier-protein] synthase (EC; 3-oxoacyl-[acyl-carrier-protein] reductase (EC; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC; Enoyl-[acyl-carrier-protein] reductase (EC; Oleoyl-[acyl-carrier-protein] hydrolase (EC]FASN FASP49327309
Annexin A1 (Annexin I) (Annexin-1) (Calpactin II) (Calpactin-2) (Chromobindin-9) (Lipocortin I) (Phospholipase A2 inhibitory protein) (p35)ANXA1 ANX1 LPC1P04083308
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)GNB1P62873308
Peroxiredoxin-6 (EC (1-Cys peroxiredoxin) (1-Cys PRX) (24 kDa protein) (Acidic calcium-independent phospholipase A2) (aiPLA2) (EC 3.1.1.-) (Antioxidant protein 2) (Liver 2D page spot 40) (Non-selenium glutathione peroxidase) (NSGPx) (EC (Red blood cells page spot 12)PRDX6 AOP2 KIAA0106P30041308
Alpha-actinin-4 (Non-muscle alpha-actinin 4)ACTN4O43707307
Serum albuminALB GIG20 GIG42 PRO0903 PRO1708 PRO2044 PRO2619 PRO2675 UNQ696/PRO1341P02768306
Talin-1TLN1 KIAA1027 TLNQ9Y490306
Ras-related protein Rab-5C (L1880) (RAB5L)RAB5C RABLP51148303
Ras-related protein Rap-1b (GTP-binding protein smg p21B)RAP1B OK/SW-cl.11P61224302
Ras-related protein Rab-10RAB10P61026301
Adenosylhomocysteinase (AdoHcyase) (EC (S-adenosyl-L-homocysteine hydrolase)AHCY SAHHP23526300
Erythrocyte band 7 integral membrane protein (Protein 7.2b) (Stomatin)STOM BND7 EPB72P27105300
Peroxiredoxin-2 (EC (Natural killer cell-enhancing factor B) (NKEF-B) (PRP) (Thiol-specific antioxidant protein) (TSA) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1)PRDX2 NKEFB TDPX1P32119299
Hemoglobin subunit alpha (Alpha-globin) (Hemoglobin alpha chain)HBA1; HBA2P69905298
Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein)GNAI2 GNAI2BP04899297
Gelsolin (AGEL) (Actin-depolymerizing factor) (ADF) (Brevin)GSNP06396295
Apolipoprotein E (Apo-E)APOEP02649294
Glucose-6-phosphate isomerase (GPI) (EC (Autocrine motility factor) (AMF) (Neuroleukin) (NLK) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) (Sperm antigen 36) (SA-36)GPIP06744293
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta)CCT2 99D8.1 CCTBP78371293
Cell division control protein 42 homolog (G25K GTP-binding protein)CDC42P60953292
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)FLNA FLN FLN1P21333292
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27)HSPB1 HSP27 HSP28P04792292
Alpha-2-macroglobulin (Alpha-2-M) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5)A2M CPAMD5 FWP007P01023288
Complement C3 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1) [Cleaved into: Complement C3 beta chain; C3-beta-c (C3bc); Complement C3 alpha chain; C3a anaphylatoxin; Acylation stimulating protein (ASP) (C3adesArg); Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2]C3 CPAMD1P01024288
Basigin (5F7) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (Leukocyte activation antigen M6) (OK blood group antigen) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (CD antigen CD147)BSG UNQ6505/PRO21383P35613286
Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Tumor rejection antigen 1) (gp96 homolog)HSP90B1 GRP94 TRA1P14625286
Transgelin-2 (Epididymis tissue protein Li 7e) (SM22-alpha homolog)TAGLN2 KIAA0120 CDABP0035P37802286
Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)]TFRCP02786284
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)ACTN1P12814282
Ras GTPase-activating-like protein IQGAP1 (p195)IQGAP1 KIAA0051P46940281
Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain)TUBB4B TUBB2CP68371281
Glutathione S-transferase P (EC (GST class-pi) (GSTP1-1)GSTP1 FAEES3 GST3P09211279
Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2)GDI2 RABGDIBP50395279
Adenylyl cyclase-associated protein 1 (CAP 1)CAP1 CAPQ01518278
Clusterin (Aging-associated gene 4 protein) (Apolipoprotein J) (Apo-J) (Complement cytolysis inhibitor) (CLI) (Complement-associated protein SP-40,40) (Ku70-binding protein 1) (NA1/NA2) (Testosterone-repressed prostate message 2) (TRPM-2) [Cleaved into: Clusterin beta chain (ApoJalpha) (Complement cytolysis inhibitor a chain); Clusterin alpha chain (ApoJbeta) (Complement cytolysis inhibitor b chain)]CLU APOJ CLI KUB1 AAG4P10909278
Ras-related protein Rab-1A (YPT1-related protein)RAB1A RAB1P62820278
T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (Renal carcinoma antigen NY-REN-15)CCT8 C21orf112 CCTQ KIAA0002P50990278
Ubiquitin-like modifier-activating enzyme 1 (EC (Protein A1S9) (Ubiquitin-activating enzyme E1)UBA1 A1S9T UBE1P22314277
Vinculin (Metavinculin) (MV)VCLP18206276
EH domain-containing protein 1 (PAST homolog 1) (hPAST1) (Testilin)EHD1 PAST PAST1 CDABP0131Q9H4M9273
GTP-binding nuclear protein Ran (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)RAN ARA24 OK/SW-cl.81P62826272
Phosphoglycerate mutase 1 (EC (EC (BPG-dependent PGAM 1) (Phosphoglycerate mutase isozyme B) (PGAM-B)PGAM1 PGAMA CDABP0006P18669272
Annexin A11 (56 kDa autoantigen) (Annexin XI) (Annexin-11) (Calcyclin-associated annexin 50) (CAP-50)ANXA11 ANX11P50995271
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC (ATP-dependent RNA helicase eIF4A-1)EIF4A1 DDX2A EIF4AP60842270
14-3-3 protein eta (Protein AS1)YWHAH YWHA1Q04917269
Annexin A6 (67 kDa calelectrin) (Annexin VI) (Annexin-6) (Calphobindin-II) (CPB-II) (Chromobindin-20) (Lipocortin VI) (Protein III) (p68) (p70)ANXA6 ANX6P08133268
Myosin light polypeptide 6 (17 kDa myosin light chain) (LC17) (Myosin light chain 3) (MLC-3) (Myosin light chain alkali 3) (Myosin light chain A3) (Smooth muscle and nonmuscle myosin light chain alkali 6)MYL6P60660268
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha)TCP1 CCT1 CCTAP17987268
Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)KRT10 KPPP13645266
Thrombospondin-1THBS1 TSP TSP1P07996266
ATP-citrate synthase (EC (ATP-citrate (pro-S-)-lyase) (ACL) (Citrate cleavage enzyme)ACLYP53396265
Programmed cell death protein 6 (Apoptosis-linked gene 2 protein homolog) (ALG-2)PDCD6 ALG2O75340265
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (G protein subunit beta-2) (Transducin beta chain 2)GNB2P62879264
Proteasome subunit alpha type-7 (EC (Proteasome subunit RC6-1) (Proteasome subunit XAPC7)PSMA7 HSPCO14818263
Ras-related protein Ral-ARALA RALP11233263
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