EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


The downloaded CSV file is not exactly the same as the displayed table. Opening CSV file with Excel can impair its content.

Protein name Gene symbol UniProt accession Identification number
Vesicle-associated membrane protein 8 (VAMP-8) (Endobrevin) (EDB)VAMP8Q9BV40132
Charged multivesicular body protein 1b (CHMP1.5) (Chromatin-modifying protein 1b) (CHMP1b) (Vacuolar protein sorting-associated protein 46-2) (Vps46-2) (hVps46-2)CHMP1B C18orf2Q7LBR1131
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit) (RIBIIR) (Ribophorin II) (RPN-II) (Ribophorin-2)RPN2P04844131
Epidermal growth factor receptor (EC (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)EGFR ERBB ERBB1 HER1P00533131
NEDD8-conjugating enzyme Ubc12 (EC 6.3.2.-) (NEDD8 carrier protein) (NEDD8 protein ligase) (Ubiquitin-conjugating enzyme E2 M)UBE2M UBC12P61081131
Phosphoserine aminotransferase (EC (Phosphohydroxythreonine aminotransferase) (PSAT)PSAT1 PSAQ9Y617131
Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)LIN7C MALS3 VELI3Q9NUP9131
Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Phorbol ester induced gene 1) (PEIG-1) (Retinoic acid-induced gene 1 protein) (RAIG-1)GPRC5A GPCR5A RAI3 RAIG1Q8NFJ5131
SH3 domain-binding glutamic acid-rich-like protein 3 (SH3 domain-binding protein 1) (SH3BP-1)SH3BGRL3 P1725Q9H299131
Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84)STAT1P42224131
COP9 signalosome complex subunit 4 (SGN4) (Signalosome subunit 4) (JAB1-containing signalosome subunit 4)COPS4 CSN4Q9BT78130
Epithelial cell adhesion molecule (Ep-CAM) (Adenocarcinoma-associated antigen) (Cell surface glycoprotein Trop-1) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Epithelial glycoprotein 314) (EGP314) (hEGP314) (KS 1/4 antigen) (KSA) (Major gastrointestinal tumor-associated protein GA733-2) (Tumor-associated calcium signal transducer 1) (CD antigen CD326)EPCAM GA733-2 M1S2 M4S1 MIC18 TACSTD1 TROP1P16422130
Eukaryotic translation initiation factor 3 subunit D (eIF3d) (Eukaryotic translation initiation factor 3 subunit 7) (eIF-3-zeta) (eIF3 p66)EIF3D EIF3S7O15371130
Eukaryotic translation initiation factor 3 subunit K (eIF3k) (Eukaryotic translation initiation factor 3 subunit 12) (Muscle-specific gene M9 protein) (PLAC-24) (eIF-3 p25) (eIF-3 p28)EIF3K EIF3S12 ARG134 HSPC029 MSTP001 PTD001Q9UBQ5130
HLA class I histocompatibility antigen, A-2 alpha chain (MHC class I antigen A*2)HLA-A HLAAP01892130
Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13)KRT13P13646130
Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC (Density-enhanced phosphatase 1) (DEP-1) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (CD antigen CD148)PTPRJ DEP1Q12913130
ADP-ribosylation factor-like protein 8B (ADP-ribosylation factor-like protein 10C) (Novel small G protein indispensable for equal chromosome segregation 1)ARL8B ARL10C GIE1Q9NVJ2129
Aflatoxin B1 aldehyde reductase member 2 (EC 1.1.1.n11) (AFB1 aldehyde reductase 1) (AFB1-AR 1) (Aldoketoreductase 7) (Succinic semialdehyde reductase) (SSA reductase)AKR7A2 AFAR AFAR1 AKR7O43488129
ATP synthase subunit O, mitochondrial (Oligomycin sensitivity conferral protein) (OSCP)ATP5O ATPOP48047129
Calmodulin-1CALM1 CALM CAM CAM1P0DP23129
Coronin-1A (Coronin-like protein A) (Clipin-A) (Coronin-like protein p57) (Tryptophan aspartate-containing coat protein) (TACO)CORO1A CORO1P31146129
DnaJ homolog subfamily B member 11 (APOBEC1-binding protein 2) (ABBP-2) (DnaJ protein homolog 9) (ER-associated DNAJ) (ER-associated Hsp40 co-chaperone) (Endoplasmic reticulum DNA J domain-containing protein 3) (ER-resident protein ERdj3) (ERdj3) (ERj3p) (HEDJ) (Human DnaJ protein 9) (hDj-9) (PWP1-interacting protein 4)DNAJB11 EDJ ERJ3 HDJ9 PSEC0121 UNQ537/PRO1080Q9UBS4129
Dynactin subunit 2 (50 kDa dynein-associated polypeptide) (Dynactin complex 50 kDa subunit) (DCTN-50) (p50 dynamitin)DCTN2 DCTN50Q13561129
Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC (ATP-dependent RNA helicase eIF4A-2)EIF4A2 DDX2B EIF4FQ14240129
Glyoxylate reductase/hydroxypyruvate reductase (EC (EC GLXR MSTP035Q9UBQ7129
Heme-binding protein 1 (p22HBP)HEBP1 HBPQ9NRV9129
Protein arginine N-methyltransferase 5 (EC (72 kDa ICln-binding protein) (Histone-arginine N-methyltransferase PRMT5) (Jak-binding protein 1) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog) (SKB1Hs) [Cleaved into: Protein arginine N-methyltransferase 5, N-terminally processed]PRMT5 HRMT1L5 IBP72 JBP1 SKB1O14744129
U5 small nuclear ribonucleoprotein 200 kDa helicase (EC (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD)SNRNP200 ASCC3L1 HELIC2 KIAA0788O75643129
60S ribosomal protein L26 (Large ribosomal subunit protein uL24)RPL26P61254128
Acetyl-CoA acetyltransferase, mitochondrial (EC (Acetoacetyl-CoA thiolase) (T2)ACAT1 ACAT MATP24752128
Calcineurin B homologous protein 1 (Calcineurin B-like protein) (Calcium-binding protein CHP) (Calcium-binding protein p22) (EF-hand calcium-binding domain-containing protein p22)CHP1 CHPQ99653128
Eukaryotic translation initiation factor 3 subunit H (eIF3h) (Eukaryotic translation initiation factor 3 subunit 3) (eIF-3-gamma) (eIF3 p40 subunit)EIF3H EIF3S3O15372128
Hemopexin (Beta-1B-glycoprotein)HPXP02790128
Myeloid-associated differentiation marker (Protein SB135)MYADM UNQ553/PRO1110Q96S97128
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (EC (Lysyl hydroxylase 3) (LH3)PLOD3O60568128
Syndecan-4 (SYND4) (Amphiglycan) (Ryudocan core protein)SDC4P31431128
Vacuolar protein sorting-associated protein 29 (hVPS29) (PEP11 homolog) (Vesicle protein sorting 29)VPS29 DC15 DC7 MDS007Q9UBQ0128
cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue-specific extinguisher 1) (TSE1) [Cleaved into: cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed]PRKAR1A PKR1 PRKAR1 TSE1P10644127
Histone H3.3H3F3A H3.3A H3F3 PP781; H3F3B H3.3BP84243127
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTULQ14160127
Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho)LAMTOR1 C11orf59 PDRO PP7157Q6IAA8127
Tenascin (TN) (Cytotactin) (GMEM) (GP 150-225) (Glioma-associated-extracellular matrix antigen) (Hexabrachion) (JI) (Myotendinous antigen) (Neuronectin) (Tenascin-C) (TN-C)TNC HXBP24821127
40S ribosomal protein S27 (Metallopan-stimulin 1) (MPS-1) (Small ribosomal subunit protein eS27)RPS27 MPS1P42677126
Adenylosuccinate synthetase isozyme 2 (AMPSase 2) (AdSS 2) (EC (Adenylosuccinate synthetase, acidic isozyme) (Adenylosuccinate synthetase, liver isozyme) (L-type adenylosuccinate synthetase) (IMP--aspartate ligase 2)ADSS ADSS2P30520126
Amyloid beta A4 protein (ABPP) (APPI) (APP) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Beta-amyloid precursor protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID(50)) (Gamma-CTF(50)); C31]APP A4 AD1P05067126
Gamma-glutamylcyclotransferase (EC (Cytochrome c-releasing factor 21)GGCT C7orf24 CRF21O75223126
GTP-binding protein Rheb (Ras homolog enriched in brain)RHEB RHEB2Q15382126
Immunoglobulin heavy constant gamma 1 (Ig gamma-1 chain C region) (Ig gamma-1 chain C region EU) (Ig gamma-1 chain C region KOL) (Ig gamma-1 chain C region NIE)IGHG1P01857126
Laminin subunit beta-2 (Laminin B1s chain) (Laminin-11 subunit beta) (Laminin-14 subunit beta) (Laminin-15 subunit beta) (Laminin-3 subunit beta) (Laminin-4 subunit beta) (Laminin-7 subunit beta) (Laminin-9 subunit beta) (S-laminin subunit beta) (S-LAM beta)LAMB2 LAMSP55268126
Myotrophin (Protein V-1)MTPNP58546126
Proteasome subunit beta type-7 (EC (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z)PSMB7 ZQ99436126
ADP-ribosylation factor-like protein 3ARL3 ARFL3P36405125
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43) [Cleaved into: Endothelial monocyte-activating polypeptide 2 (EMAP-2) (Endothelial monocyte-activating polypeptide II) (EMAP-II) (Small inducible cytokine subfamily E member 1)]AIMP1 EMAP2 SCYE1Q12904125
Cathepsin B (EC (APP secretase) (APPS) (Cathepsin B1) [Cleaved into: Cathepsin B light chain; Cathepsin B heavy chain]CTSB CPSBP07858125
DnaJ homolog subfamily B member 1 (DnaJ protein homolog 1) (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40) (Human DnaJ protein 1) (hDj-1)DNAJB1 DNAJ1 HDJ1 HSPF1P25685125
General vesicular transport factor p115 (Protein USO1 homolog) (Transcytosis-associated protein) (TAP) (Vesicle-docking protein)USO1 VDPO60763125
GTP-binding protein SAR1a (COPII-associated small GTPase)SAR1A SAR1 SARA SARA1Q9NR31125
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas)GNAS GNAS1Q5JWF2125
Histone H2B type 2-E (Histone H2B-GL105) (Histone H2B.q) (H2B/q)HIST2H2BE H2BFQQ16778125
Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK-6A) (Cytokeratin-6D) (CK-6D) (Keratin-6A) (K6A) (Type-II keratin Kb6) (allergen Hom s 5)KRT6A K6A KRT6DP02538125
Phospholipid scramblase 3 (PL scramblase 3) (Ca(2+)-dependent phospholipid scramblase 3)PLSCR3Q9NRY6125
Prohibitin-2 (B-cell receptor-associated protein BAP37) (D-prohibitin) (Repressor of estrogen receptor activity)PHB2 BAP REAQ99623125
Transmembrane emp24 domain-containing protein 9 (GMP25) (Glycoprotein 25L2) (p24 family protein alpha-2) (p24alpha2) (p25)TMED9 GP25L2Q9BVK6125
Vacuolar protein-sorting-associated protein 25 (hVps25) (Dermal papilla-derived protein 9) (ELL-associated protein of 20 kDa) (ESCRT-II complex subunit VPS25)VPS25 DERP9 EAP20Q9BRG1125
60S ribosomal protein L32 (Large ribosomal subunit protein eL32)RPL32 PP9932P62910124
Collagen alpha-1(I) chain (Alpha-1 type I collagen)COL1A1P02452124
D-dopachrome decarboxylase (EC (D-dopachrome tautomerase) (Phenylpyruvate tautomerase II)DDTP30046124
E3 ubiquitin-protein ligase HUWE1 (EC (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (HECT-type E3 ubiquitin transferase HUWE1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1)HUWE1 KIAA0312 KIAA1578 UREB1 HSPC272Q7Z6Z7124
Eukaryotic translation elongation factor 1 epsilon-1 (Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3) (Elongation factor p18) (Multisynthase complex auxiliary component p18)EEF1E1 AIMP3 P18O43324124
Glutaredoxin-3 (PKC-interacting cousin of thioredoxin) (PICOT) (PKC-theta-interacting protein) (PKCq-interacting protein) (Thioredoxin-like protein 2)GLRX3 PICOT TXNL2 HUSSY-22O76003124
Lamin-B1LMNB1 LMN2 LMNBP20700124
Lupus La protein (La autoantigen) (La ribonucleoprotein) (Sjoegren syndrome type B antigen) (SS-B)SSBP05455124
Rho GTPase-activating protein 1 (CDC42 GTPase-activating protein) (GTPase-activating protein rhoGAP) (Rho-related small GTPase protein activator) (Rho-type GTPase-activating protein 1) (p50-RhoGAP)ARHGAP1 CDC42GAP RHOGAP1Q07960124
S-adenosylhomocysteine hydrolase-like protein 1 (DC-expressed AHCY-like molecule) (IP(3)Rs binding protein released with IP(3)) (IRBIT) (Putative adenosylhomocysteinase 2) (S-adenosyl-L-homocysteine hydrolase 2) (AdoHcyase 2)AHCYL1 DCAL IRBIT XPVKONAO43865124
Tubulointerstitial nephritis antigen-like (Glucocorticoid-inducible protein 5) (Oxidized LDL-responsive gene 2 protein) (OLRG-2) (Tubulointerstitial nephritis antigen-related protein) (TIN Ag-related protein) (TIN-Ag-RP)TINAGL1 GIS5 LCN7 OLRG2 TINAGL PP6614 PSEC0088 UNQ204/PRO230Q9GZM7124
Vacuolar protein sorting-associated protein 26A (Vesicle protein sorting 26A) (hVPS26)VPS26A VPS26O75436124
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (Multisynthase complex auxiliary component p38) (Protein JTV-1)AIMP2 JTV1 PRO0992Q13155123
Anoctamin-6 (Small-conductance calcium-activated nonselective cation channel) (SCAN channel) (Transmembrane protein 16F)ANO6 TMEM16FQ4KMQ2123
Aspartate aminotransferase, mitochondrial (mAspAT) (EC (EC (Fatty acid-binding protein) (FABP-1) (Glutamate oxaloacetate transaminase 2) (Kynurenine aminotransferase 4) (Kynurenine aminotransferase IV) (Kynurenine--oxoglutarate transaminase 4) (Kynurenine--oxoglutarate transaminase IV) (Plasma membrane-associated fatty acid-binding protein) (FABPpm) (Transaminase A)GOT2P00505123
Cyclin-dependent kinase 1 (CDK1) (EC (EC (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)CDK1 CDC2 CDC28A CDKN1 P34CDC2P06493123
DnaJ homolog subfamily C member 5 (Ceroid-lipofuscinosis neuronal protein 4) (Cysteine string protein) (CSP)DNAJC5 CLN4Q9H3Z4123
EF-hand domain-containing protein D2 (Swiprosin-1)EFHD2 SWS1Q96C19123
Eukaryotic translation initiation factor 5 (eIF-5)EIF5P55010123
Glucosidase 2 subunit beta (80K-H protein) (Glucosidase II subunit beta) (Protein kinase C substrate 60.1 kDa protein heavy chain) (PKCSH)PRKCSH G19P1P14314123
Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1)KIF23 KNSL5 MKLP1Q02241123
Pre-mRNA-processing factor 19 (EC (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)PRPF19 NMP200 PRP19 SNEVQ9UMS4123
Tripeptidyl-peptidase 1 (TPP-1) (EC (Cell growth-inhibiting gene 1 protein) (Lysosomal pepstatin-insensitive protease) (LPIC) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase I) (TPP-I)TPP1 CLN2 GIG1 UNQ267/PRO304O14773123
Tubulin beta-1 chainTUBB1Q9H4B7123
ATP-dependent RNA helicase DDX1 (EC (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB)DDX1Q92499122
Basic leucine zipper and W2 domain-containing protein 1 (Protein Orf)BZW1 BZAP45 KIAA0005Q7L1Q6122
Gamma-glutamyl hydrolase (EC (Conjugase) (GH) (Gamma-Glu-X carboxypeptidase)GGHQ92820122
Glutamate dehydrogenase 1, mitochondrial (GDH 1) (EC GLUDP00367122
Integral membrane protein 2B (Immature BRI2) (imBRI2) (Protein E25B) (Transmembrane protein BRI) (Bri) [Cleaved into: BRI2, membrane form (Mature BRI2) (mBRI2); BRI2 intracellular domain (BRI2 ICD); BRI2C, soluble form; Bri23 peptide (Bri2-23) (ABri23) (C-terminal peptide) (P23 peptide)]ITM2B BRI BRI2Q9Y287122
Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC (ICD-M) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)IDH2P48735122
Membrane cofactor protein (TLX) (Trophoblast leukocyte common antigen) (CD antigen CD46)CD46 MCP MIC10P15529122
Protein flightless-1 homologFLII FLILQ13045122
Rho GDP-dissociation inhibitor 2 (Rho GDI 2) (Ly-GDI) (Rho-GDI beta)ARHGDIB GDIA2 GDID4 RAP1GN1P52566122
Ribose-phosphate pyrophosphokinase 1 (EC (PPRibP) (Phosphoribosyl pyrophosphate synthase I) (PRS-I)PRPS1P60891122
Serine protease HTRA1 (EC 3.4.21.-) (High-temperature requirement A serine peptidase 1) (L56) (Serine protease 11)HTRA1 HTRA PRSS11Q92743122
< [9] [10] [11] [12] [13] [14] [15] [16] [17] [18] >