EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1)DIAPH1 DIAP1O60610113
Rho-associated protein kinase 2 (EC (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)ROCK2 KIAA0619O75116113
Sodium-coupled neutral amino acid transporter 2 (Amino acid transporter A2) (Protein 40-9-1) (Solute carrier family 38 member 2) (System A amino acid transporter 2) (System A transporter 1) (System N amino acid transporter 2)SLC38A2 ATA2 KIAA1382 SAT2 SNAT2Q96QD8113
Synaptogyrin-2 (Cellugyrin)SYNGR2 UNQ352/PRO615O43760113
UPF0568 protein C14orf166 (CLE7 homolog) (CLE)C14orf166 CGI-99Q9Y224113
Zinc-alpha-2-glycoprotein (Zn-alpha-2-GP) (Zn-alpha-2-glycoprotein)AZGP1 ZAG ZNGP1P25311113
60S ribosomal protein L29 (Cell surface heparin-binding protein HIP) (Large ribosomal subunit protein eL29)RPL29P47914112
Apolipoprotein D (Apo-D) (ApoD)APODP05090112
Cysteine-rich and transmembrane domain-containing protein 1CYSTM1 C5orf32 ORF1-FL49Q9H1C7112
Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220)EIF4G1 EIF4F EIF4G EIF4GIQ04637112
Inactive tyrosine-protein kinase 7 (Colon carcinoma kinase 4) (CCK-4) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7)PTK7 CCK4Q13308112
Leucine-rich PPR motif-containing protein, mitochondrial (130 kDa leucine-rich protein) (LRP 130) (GP130)LRPPRC LRP130P42704112
Leucine-rich repeat-containing protein 47LRRC47 KIAA1185Q8N1G4112
Lipolysis-stimulated lipoprotein receptorLSR LISCHQ86X29112
Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT) (Formylglycinamide ribotide amidotransferase)PFAS KIAA0361O15067112
Prolyl endopeptidase (PE) (EC (Post-proline cleaving enzyme)PREP PEPP48147112
Protein TFG (TRK-fused gene protein)TFGQ92734112
Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC (EC (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1)G3BP1 G3BPQ13283112
Small nuclear ribonucleoprotein E (snRNP-E) (Sm protein E) (Sm-E) (SmE)SNRPEP62304112
Sodium bicarbonate cotransporter 3 (Electroneutral Na/HCO(3) cotransporter) (Sodium bicarbonate cotransporter 2) (Sodium bicarbonate cotransporter 2b) (Bicarbonate transporter) (Solute carrier family 4 member 7)SLC4A7 BT NBC2 NBC2B NBC3 NBCn1 SBC2 SLC4A6Q9Y6M7112
Superoxide dismutase [Mn], mitochondrial (EC
Thioredoxin domain-containing protein 5 (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Thioredoxin-like protein p46)TXNDC5 TLP46 UNQ364/PRO700Q8NBS9112
Adenylate kinase 2, mitochondrial (AK 2) (EC (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) [Cleaved into: Adenylate kinase 2, mitochondrial, N-terminally processed]AK2 ADK2P54819111
Complement C1r subcomponent (EC (Complement component 1 subcomponent r) [Cleaved into: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain]C1RP00736111
Complement C4-B (Basic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3) [Cleaved into: Complement C4 beta chain; Complement C4-B alpha chain; C4a anaphylatoxin; C4b-B; C4d-B; Complement C4 gamma chain]C4B CO4 CPAMD3; C4B_2P0C0L5111
EGF-containing fibulin-like extracellular matrix protein 1 (Extracellular protein S1-5) (Fibrillin-like protein) (Fibulin-3) (FIBL-3)EFEMP1 FBLN3 FBNLQ12805111
Elongin-C (EloC) (Elongin 15 kDa subunit) (RNA polymerase II transcription factor SIII subunit C) (SIII p15) (Transcription elongation factor B polypeptide 1)ELOC TCEB1Q15369111
HLA class I histocompatibility antigen, A-24 alpha chain (Aw-24) (HLA class I histocompatibility antigen, A-9 alpha chain) (MHC class I antigen A*24)HLA-A HLAAP05534111
Polymerase I and transcript release factor (Cavin-1)PTRF FKSG13Q6NZI2111
S-methyl-5'-thioadenosine phosphorylase (EC (5'-methylthioadenosine phosphorylase) (MTA phosphorylase) (MTAP) (MTAPase)MTAP MSAPQ13126111
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)SQSTM1 ORCA OSILQ13501111
Apolipoprotein A-IV (Apo-AIV) (ApoA-IV) (Apolipoprotein A4)APOA4P06727110
Disintegrin and metalloproteinase domain-containing protein 9 (ADAM 9) (EC 3.4.24.-) (Cellular disintegrin-related protein) (Meltrin-gamma) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase)ADAM9 KIAA0021 MCMP MDC9 MLTNGQ13443110
Electron transfer flavoprotein subunit beta (Beta-ETF)ETFB FP585P38117110
Leucine-rich repeat-containing protein 59 (Ribosome-binding protein p34) (p34)LRRC59 PRO1855Q96AG4110
Ras-related protein Rab-23RAB23 HSPC137Q9ULC3110
Ubiquitin-conjugating enzyme E2 K (EC (E2 ubiquitin-conjugating enzyme K) (Huntingtin-interacting protein 2) (HIP-2) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-25 kDa) (Ubiquitin-conjugating enzyme E2(25K)) (Ubiquitin-conjugating enzyme E2-25K) (Ubiquitin-protein ligase)UBE2K HIP2 LIGP61086110
V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1)ATP6V0A1 ATP6N1 ATP6N1A VPP1Q93050110
26S proteasome non-ATPase regulatory subunit 8 (26S proteasome regulatory subunit RPN12) (26S proteasome regulatory subunit S14) (p31)PSMD8P48556109
Collagen alpha-2(IV) chain [Cleaved into: Canstatin]COL4A2P08572109
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1P63167109
Gamma-glutamyltranspeptidase 1 (GGT 1) (EC (Gamma-glutamyltransferase 1) (Glutathione hydrolase 1) (EC (Leukotriene-C4 hydrolase) (EC (CD antigen CD224) [Cleaved into: Gamma-glutamyltranspeptidase 1 heavy chain; Gamma-glutamyltranspeptidase 1 light chain]GGT1 GGTP19440109
Glyoxalase domain-containing protein 4GLOD4 C17orf25 CGI-150 My027Q9HC38109
GMP synthase [glutamine-hydrolyzing] (EC (GMP synthetase) (Glutamine amidotransferase)GMPSP49915109
High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter)SLC7A1 ATRC1 ERR REC1LP30825109
HornerinHRNR S100A18Q86YZ3109
Keratin, type I cytoskeletal 17 (39.1) (Cytokeratin-17) (CK-17) (Keratin-17) (K17)KRT17Q04695109
Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Type-II keratin Kb8)KRT8 CYK8P05787109
Mitotic checkpoint protein BUB3BUB3O43684109
Plasminogen activator inhibitor 1 RNA-binding protein (PAI1 RNA-binding protein 1) (PAI-RBP1) (SERPINE1 mRNA-binding protein 1)SERBP1 PAIRBP1 CGI-55Q8NC51109
Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220)PRPF8 PRPC8Q6P2Q9109
Prefoldin subunit 2PFDN2 PFD2 HSPC231Q9UHV9109
Protein ABHD14B (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 14B) (Abhydrolase domain-containing protein 14B) (CCG1-interacting factor B)ABHD14B CIBQ96IU4109
Protein AMBP [Cleaved into: Alpha-1-microglobulin (Protein HC) (Alpha-1 microglycoprotein) (Complex-forming glycoprotein heterogeneous in charge); Inter-alpha-trypsin inhibitor light chain (ITI-LC) (Bikunin) (EDC1) (HI-30) (Uronic-acid-rich protein); Trypstatin]AMBP HCP ITILP02760109
Protein FAM3C (Interleukin-like EMT inducer)FAM3C ILEI GS3786Q92520109
Rac GTPase-activating protein 1 (Male germ cell RacGap) (MgcRacGAP) (Protein CYK4 homolog) (CYK4) (HsCYK-4)RACGAP1 KIAA1478 MGCRACGAPQ9H0H5109
Solute carrier family 2, facilitated glucose transporter member 3 (Glucose transporter type 3, brain) (GLUT-3)SLC2A3 GLUT3P11169109
Trifunctional enzyme subunit alpha, mitochondrial (78 kDa gastrin-binding protein) (TP-alpha) [Includes: Long-chain enoyl-CoA hydratase (EC; Long chain 3-hydroxyacyl-CoA dehydrogenase (EC]HADHA HADHP40939109
Zinc transporter ZIP14 (LIV-1 subfamily of ZIP zinc transporter 4) (LZT-Hs4) (Solute carrier family 39 member 14) (Zrt- and Irt-like protein 14) (ZIP-14)SLC39A14 KIAA0062 ZIP14Q15043109
Beta-2-glycoprotein 1 (APC inhibitor) (Activated protein C-binding protein) (Anticardiolipin cofactor) (Apolipoprotein H) (Apo-H) (Beta-2-glycoprotein I) (B2GPI) (Beta(2)GPI)APOH B2G1P02749108
Complement decay-accelerating factor (CD antigen CD55)CD55 CR DAFP08174108
Cystatin-C (Cystatin-3) (Gamma-trace) (Neuroendocrine basic polypeptide) (Post-gamma-globulin)CST3P01034108
Dipeptidyl peptidase 1 (EC (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)]CTSC CPPIP53634108
Glucosamine-6-phosphate isomerase 1 (EC (Glucosamine-6-phosphate deaminase 1) (GNPDA 1) (GlcN6P deaminase 1) (Oscillin)GNPDA1 GNPI HLN KIAA0060P46926108
Integrin beta-4 (GP150) (CD antigen CD104)ITGB4P16144108
Interferon-induced transmembrane protein 3 (Dispanin subfamily A member 2b) (DSPA2b) (Interferon-inducible protein 1-8U)IFITM3Q01628108
Melanotransferrin (Melanoma-associated antigen p97) (CD antigen CD228)MELTF MAP97 MFI2P08582108
MOB kinase activator 1A (Mob1 alpha) (Mob1A) (Mob1 homolog 1B) (Mps one binder kinase activator-like 1B)MOB1A C2orf6 MOB4B MOBK1B MOBKL1BQ9H8S9108
Protein transport protein Sec24C (SEC24-related protein C)SEC24C KIAA0079P53992108
Translin (EC 3.1.-.-) (Component 3 of promoter of RISC) (C3PO)TSNQ15631108
Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13) (Zinc finger CCCH domain-containing protein 2) (Zinc finger antiviral protein) (ZAP)ZC3HAV1 ZC3HDC2 PRO1677Q7Z2W4108
Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146)MCAM MUC18P43121107
Glycylpeptide N-tetradecanoyltransferase 1 (EC (Myristoyl-CoA:protein N-myristoyltransferase 1) (NMT 1) (Type I N-myristoyltransferase) (Peptide N-myristoyltransferase 1)NMT1 NMTP30419107
Heat shock 70 kDa protein 1-like (Heat shock 70 kDa protein 1L) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom)HSPA1LP34931107
Peroxisomal multifunctional enzyme type 2 (MFE-2) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-bifunctional protein) (DBP) (Multifunctional protein 2) (MPF-2) (Short chain dehydrogenase/reductase family 8C member 1) [Cleaved into: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC (EC (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase)]HSD17B4 EDH17B4 SDR8C1P51659107
Phenylalanine--tRNA ligase beta subunit (EC (Phenylalanyl-tRNA synthetase beta subunit) (PheRS)FARSB FARSLB FRSB HSPC173Q9NSD9107
Protein ERGIC-53 (ER-Golgi intermediate compartment 53 kDa protein) (Gp58) (Intracellular mannose-specific lectin MR60) (Lectin mannose-binding 1)LMAN1 ERGIC53 F5F8DP49257107
Protein Niban (Cell growth-inhibiting gene 39 protein) (Protein FAM129A)FAM129A C1orf24 NIBAN GIG39Q9BZQ8107
Protein S100-A13 (S100 calcium-binding protein A13)S100A13Q99584107
Ran GTPase-activating protein 1 (RanGAP1)RANGAP1 KIAA1835 SDP46060107
Secretory carrier-associated membrane protein 2 (Secretory carrier membrane protein 2)SCAMP2O15127107
Syndecan-1 (SYND1) (CD antigen CD138)SDC1 SDCP18827107
Unconventional myosin-Ie (Myosin-Ic) (Unconventional myosin 1E)MYO1E MYO1CQ12965107
Beta-galactosidase (EC (Acid beta-galactosidase) (Lactase) (Elastin receptor 1)GLB1 ELNR1P16278106
Complement component 1 Q subcomponent-binding protein, mitochondrial (ASF/SF2-associated protein p32) (Glycoprotein gC1qBP) (C1qBP) (Hyaluronan-binding protein 1) (Mitochondrial matrix protein p32) (gC1q-R protein) (p33)C1QBP GC1QBP HABP1 SF2P32Q07021106
Cytochrome b-c1 complex subunit 2, mitochondrial (Complex III subunit 2) (Core protein II) (Ubiquinol-cytochrome-c reductase complex core protein 2)UQCRC2P22695106
DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8)DNAJC13 KIAA0678 RME8O75165106
ELAV-like protein 1 (Hu-antigen R) (HuR)ELAVL1 HURQ15717106
Heparin cofactor 2 (Heparin cofactor II) (HC-II) (Protease inhibitor leuserpin-2) (HLS2) (Serpin D1)SERPIND1 HCF2P05546106
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)RBBP4 RBAP48Q09028106
Inter-alpha-trypsin inhibitor heavy chain H1 (ITI heavy chain H1) (ITI-HC1) (Inter-alpha-inhibitor heavy chain 1) (Inter-alpha-trypsin inhibitor complex component III) (Serum-derived hyaluronan-associated protein) (SHAP)ITIH1 IGHEP1P19827106
Interleukin enhancer-binding factor 3 (Double-stranded RNA-binding protein 76) (DRBP76) (M-phase phosphoprotein 4) (MPP4) (Nuclear factor associated with dsRNA) (NFAR) (Nuclear factor of activated T-cells 90 kDa) (NF-AT-90) (Translational control protein 80) (TCP80)ILF3 DRBF MPHOSPH4 NF90Q12906106
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (DDAH-1) (Dimethylarginine dimethylaminohydrolase 1) (EC (DDAHI) (Dimethylargininase-1)DDAH1 DDAHO94760106
N-acetyl-D-glucosamine kinase (N-acetylglucosamine kinase) (EC (GlcNAc kinase)NAGKQ9UJ70106
Omega-amidase NIT2 (EC (Nitrilase homolog 2)NIT2 CUA002Q9NQR4106
Serine hydroxymethyltransferase, cytosolic (SHMT) (EC (Glycine hydroxymethyltransferase) (Serine methylase)SHMT1P34896106
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)TRIM28 KAP1 RNF96 TIF1BQ13263106
Twinfilin-1 (Protein A6) (Protein tyrosine kinase 9)TWF1 PTK9Q12792106
Acid ceramidase (AC) (ACDase) (Acid CDase) (EC (Acylsphingosine deacylase) (N-acylsphingosine amidohydrolase) (Putative 32 kDa heart protein) (PHP32) [Cleaved into: Acid ceramidase subunit alpha; Acid ceramidase subunit beta]ASAH1 ASAH HSD-33 HSD33Q13510105
Dipeptidyl peptidase 3 (EC (Dipeptidyl aminopeptidase III) (Dipeptidyl arylamidase III) (Dipeptidyl peptidase III) (DPP III) (Enkephalinase B)DPP3Q9NY33105
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