EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
Histone H1.5 (Histone H1a) (Histone H1b) (Histone H1s-3)HIST1H1B H1F5P16401140
Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)KRT19P08727140
Neuroplastin (Stromal cell-derived receptor 1) (SDR-1)NPTN SDFR1 SDR1Q9Y639140
Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1) (Erythrocyte phospholipid scramblase) (MmTRA1b)PLSCR1O15162140
Protein arginine N-methyltransferase 1 (EC (Histone-arginine N-methyltransferase PRMT1) (Interferon receptor 1-bound protein 4)PRMT1 HMT2 HRMT1L2 IR1B4Q99873140
Tyrosine--tRNA ligase, cytoplasmic (EC (Tyrosyl-tRNA synthetase) (TyrRS) [Cleaved into: Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed]YARSP54577140
Vacuolar protein sorting-associated protein 4A (EC (Protein SKD2) (VPS4-1) (hVPS4)VPS4A VPS4Q9UN37140
60S ribosomal protein L19 (Large ribosomal subunit protein eL19)RPL19P84098139
60S ribosomal protein L28 (Large ribosomal subunit protein eL28)RPL28P46779139
Activated RNA polymerase II transcriptional coactivator p15 (Positive cofactor 4) (PC4) (SUB1 homolog) (p14)SUB1 PC4 RPO2TC1P53999139
Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3)HNRNPA3 HNRPA3P51991139
Histidine triad nucleotide-binding protein 1 (EC 3.-.-.-) (Adenosine 5'-monophosphoramidase) (Protein kinase C inhibitor 1) (Protein kinase C-interacting protein 1) (PKCI-1)HINT1 HINT PKCI1 PRKCNH1P49773139
Integrin-linked protein kinase (EC (59 kDa serine/threonine-protein kinase) (ILK-1) (ILK-2) (p59ILK)ILK ILK1 ILK2Q13418139
Macrophage-capping protein (Actin regulatory protein CAP-G)CAPG AFCP MCPP40121139
Pigment epithelium-derived factor (PEDF) (Cell proliferation-inducing gene 35 protein) (EPC-1) (Serpin F1)SERPINF1 PEDF PIG35P36955139
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC (Protein phosphatase 1C catalytic subunit)PPP1CCP36873139
Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (Sm-D autoantigen) (snRNP core protein D1)SNRPD1P62314139
V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (32 kDa accessory protein) (V-ATPase 40 kDa accessory protein) (V-ATPase AC39 subunit) (p39) (Vacuolar proton pump subunit d 1)ATP6V0D1 ATP6D VPATPDP61421139
Aminopeptidase B (AP-B) (EC (Arginine aminopeptidase) (Arginyl aminopeptidase)RNPEP APBQ9H4A4138
Histone H2A type 2-BHIST2H2ABQ8IUE6138
Lactotransferrin (Lactoferrin) (EC 3.4.21.-) (Growth-inhibiting protein 12) (Talalactoferrin) [Cleaved into: Lactoferricin-H (Lfcin-H); Kaliocin-1; Lactoferroxin-A; Lactoferroxin-B; Lactoferroxin-C]LTF GIG12 LFP02788138
Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC (Leukotriene A(4) hydrolase)LTA4H LTA4P09960138
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC (ATP-dependent RNA helicase #46) (DEAH box protein 15)DHX15 DBP1 DDX15O43143138
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI-associated protein 2) (BAI1-associated protein 2) (Protein BAP2) (Fas ligand-associated factor 3) (FLAF3) (Insulin receptor substrate p53/p58) (IRS-58) (IRSp53/58) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53)BAIAP2Q9UQB8137
Caveolin-1CAV1 CAVQ03135137
Equilibrative nucleoside transporter 1 (Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter) (Equilibrative NBMPR-sensitive nucleoside transporter) (Nucleoside transporter, es-type) (Solute carrier family 29 member 1)SLC29A1 ENT1Q99808137
Glutathione synthetase (GSH synthetase) (GSH-S) (EC (Glutathione synthase)GSSP48637137
Histone H2A type 2-A (Histone H2A.2) (Histone H2A/o)HIST2H2AA3 H2AFO HIST2H2AA; HIST2H2AA4Q6FI13137
NAD(P)H dehydrogenase [quinone] 1 (EC (Azoreductase) (DT-diaphorase) (DTD) (Menadione reductase) (NAD(P)H:quinone oxidoreductase 1) (Phylloquinone reductase) (Quinone reductase 1) (QR1)NQO1 DIA4 NMOR1P15559137
Phosphate carrier protein, mitochondrial (Phosphate transport protein) (PTP) (Solute carrier family 25 member 3)SLC25A3 PHC OK/SW-cl.48Q00325137
Proteolipid protein 2 (Differentiation-dependent protein A4) (Intestinal membrane A4 protein)PLP2 A4Q04941137
Titin (EC (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)TTNQ8WZ42137
UMP-CMP kinase (EC (Deoxycytidylate kinase) (CK) (dCMP kinase) (Nucleoside-diphosphate kinase) (EC (Uridine monophosphate/cytidine monophosphate kinase) (UMP/CMP kinase) (UMP/CMPK)CMPK1 CMK CMPK UCK UMK UMPKP30085137
Vitamin D-binding protein (DBP) (VDB) (Gc protein-derived macrophage activating factor) (Gc-MAF) (GcMAF) (Gc-globulin) (Group-specific component) (Gc) (Vitamin D-binding protein-macrophage activating factor) (DBP-maf)GCP02774137
Biliverdin reductase A (BVR A) (EC (Biliverdin-IX alpha-reductase)BLVRA BLVR BVRP53004136
Immunoglobulin heavy constant alpha 1 (Ig alpha-1 chain C region) (Ig alpha-1 chain C region BUR) (Ig alpha-1 chain C region TRO)IGHA1P01876136
Myosin-14 (Myosin heavy chain 14) (Myosin heavy chain, non-muscle IIc) (Non-muscle myosin heavy chain IIc) (NMHC II-C)MYH14 KIAA2034 FP17425Q7Z406136
Pyridoxal kinase (EC (Pyridoxine kinase)PDXK C21orf124 C21orf97 PKH PNK PRED79O00764136
Syntaxin-binding protein 2 (Protein unc-18 homolog 2) (Unc18-2) (Protein unc-18 homolog B) (Unc-18B)STXBP2 UNC18BQ15833136
Thioredoxin-dependent peroxide reductase, mitochondrial (EC (Antioxidant protein 1) (AOP-1) (HBC189) (Peroxiredoxin III) (Prx-III) (Peroxiredoxin-3) (Protein MER5 homolog)PRDX3 AOP1P30048136
60S ribosomal protein L36 (Large ribosomal subunit protein eL36)RPL36Q9Y3U8135
AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1)AP1G1 ADTG CLAPG1O43747135
COP9 signalosome complex subunit 3 (SGN3) (Signalosome subunit 3) (JAB1-containing signalosome subunit 3)COPS3 CSN3Q9UNS2135
CTP synthase 1 (EC (CTP synthetase 1) (UTP--ammonia ligase 1)CTPS1 CTPSP17812135
EH domain-containing protein 3 (PAST homolog 3)EHD3 EHD2 PAST3Q9NZN3135
eIF-2-alpha kinase activator GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1)GCN1 GCN1L1 KIAA0219Q92616135
Endoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4)ERP44 KIAA0573 TXNDC4 UNQ532/PRO1075Q9BS26135
Farnesyl pyrophosphate synthase (FPP synthase) (FPS) (EC ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC (Farnesyl diphosphate synthase) (Geranyltranstransferase)FDPS FPS KIAA1293P14324135
Glutathione reductase, mitochondrial (GR) (GRase) (EC GLUR GRD1P00390135
Glypican-1 [Cleaved into: Secreted glypican-1]GPC1P35052135
Heterogeneous nuclear ribonucleoprotein L (hnRNP L)HNRNPL HNRPL P/OKcl.14P14866135
Immunoglobulin J chain (Joining chain of multimeric IgA and IgM)JCHAIN IGCJ IGJP01591135
Keratin, type I cytoskeletal 18 (Cell proliferation-inducing gene 46 protein) (Cytokeratin-18) (CK-18) (Keratin-18) (K18)KRT18 CYK18 PIG46P05783135
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (55 kDa nuclear protein) (DNA-binding p52/p100 complex, 52 kDa subunit) (NMT55) (p54(nrb)) (p54nrb)NONO NRB54Q15233135
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)SRSF3 SFRS3 SRP20P84103135
Ubiquitin-conjugating enzyme E2 L3 (EC (E2 ubiquitin-conjugating enzyme L3) (L-UBC) (UbcH7) (Ubiquitin carrier protein L3) (Ubiquitin-conjugating enzyme E2-F1) (Ubiquitin-protein ligase L3)UBE2L3 UBCE7 UBCH7P68036135
Xaa-Pro dipeptidase (X-Pro dipeptidase) (EC (Imidodipeptidase) (Peptidase D) (Proline dipeptidase) (Prolidase)PEPD PRDP12955135
Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G)EPB41L2O43491134
Ceruloplasmin (EC (Ferroxidase)CPP00450134
Complement C4-A (Acidic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2) [Cleaved into: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain]C4A CO4 CPAMD2P0C0L4134
Coronin-1B (Coronin-2)CORO1BQ9BR76134
Desmoglein-1 (Cadherin family member 4) (Desmosomal glycoprotein 1) (DG1) (DGI) (Pemphigus foliaceus antigen)DSG1 CDHF4Q02413134
DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe)DDB1 XAP1Q16531134
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (DDOST 48 kDa subunit) (Oligosaccharyl transferase 48 kDa subunit)DDOST KIAA0115 OST48 OK/SW-cl.45P39656134
Fumarate hydratase, mitochondrial (Fumarase) (EC
Nuclear transport factor 2 (NTF-2) (Placental protein 15) (PP15)NUTF2 NTF2P61970134
Ras-related protein Rab-18RAB18Q9NP72134
Renin receptor (ATPase H(+)-transporting lysosomal accessory protein 2) (ATPase H(+)-transporting lysosomal-interacting protein 2) (ER-localized type I transmembrane adaptor) (Embryonic liver differentiation factor 10) (N14F) (Renin/prorenin receptor) (Vacuolar ATP synthase membrane sector-associated protein M8-9) (ATP6M8-9) (V-ATPase M8.9 subunit)ATP6AP2 ATP6IP2 CAPER ELDF10 HT028 MSTP009 PSEC0072O75787134
Single-stranded DNA-binding protein, mitochondrial (Mt-SSB) (MtSSB) (PWP1-interacting protein 17)SSBP1 SSBPQ04837134
Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1) (TRAF6-regulated IKK activator 1 beta Uev1A)UBE2V1 CROC1 UBE2V UEV1 P/OKcl.19Q13404134
UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1) (hUGT1) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase) (UDP-glucose ceramide glucosyltransferase-like 1)UGGT1 GT UGCGL1 UGGT UGT1 UGTRQ9NYU2134
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)EFTUD2 KIAA0031 SNRP116Q15029133
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHA1) (p38)AHSA1 C14orf3 HSPC322O95433133
Adenosine kinase (AK) (EC (Adenosine 5'-phosphotransferase)ADKP55263133
Adenylosuccinate lyase (ADSL) (ASL) (EC (Adenylosuccinase) (ASase)ADSL AMPSP30566133
B-cell receptor-associated protein 31 (BCR-associated protein 31) (Bap31) (6C6-AG tumor-associated antigen) (Protein CDM) (p28)BCAP31 BAP31 DXS1357EP51572133
CD166 antigen (Activated leukocyte cell adhesion molecule) (CD antigen CD166)ALCAM MEMDQ13740133
Cysteine and glycine-rich protein 1 (Cysteine-rich protein 1) (CRP) (CRP1) (Epididymis luminal protein 141) (HEL-141)CSRP1 CSRP CYRPP21291133
EGF-like repeat and discoidin I-like domain-containing protein 3 (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1)EDIL3 DEL1O43854133
Electron transfer flavoprotein subunit alpha, mitochondrial (Alpha-ETF)ETFAP13804133
Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)FLNC ABPL FLN2Q14315133
Importin subunit alpha-1 (Karyopherin subunit alpha-2) (RAG cohort protein 1) (SRP1-alpha)KPNA2 RCH1 SRP1P52292133
Leukocyte elastase inhibitor (LEI) (Monocyte/neutrophil elastase inhibitor) (EI) (M/NEI) (Peptidase inhibitor 2) (PI-2) (Serpin B1)SERPINB1 ELANH2 MNEI PI2P30740133
Nuclear migration protein nudC (Nuclear distribution protein C homolog)NUDCQ9Y266133
Peroxidasin homolog (EC (Melanoma-associated antigen MG50) (Vascular peroxidase 1) (p53-responsive gene 2 protein)PXDN KIAA0230 MG50 PRG2 VPO VPO1Q92626133
Platelet-activating factor acetylhydrolase IB subunit gamma (EC (PAF acetylhydrolase 29 kDa subunit) (PAF-AH 29 kDa subunit) (PAF-AH subunit gamma) (PAFAH subunit gamma)PAFAH1B3 PAFAHGQ15102133
Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22)PPP1R7 SDS22Q15435133
Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1)RANBP1P43487133
Serpin B6 (Cytoplasmic antiproteinase) (CAP) (Peptidase inhibitor 6) (PI-6) (Placental thrombin inhibitor)SERPINB6 PI6 PTIP35237133
Small nuclear ribonucleoprotein Sm D2 (Sm-D2) (snRNP core protein D2)SNRPD2 SNRPD1P62316133
Spermidine synthase (SPDSY) (EC (Putrescine aminopropyltransferase)SRM SPS1 SRML1P19623133
Abl interactor 1 (Abelson interactor 1) (Abi-1) (Abl-binding protein 4) (AblBP4) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Nap1-binding protein) (Nap1BP) (Spectrin SH3 domain-binding protein 1) (e3B1)ABI1 SSH3BP1Q8IZP0132
Collagen alpha-1(XII) chainCOL12A1 COL12A1LQ99715132
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)DCTN1Q14203132
Glia-derived nexin (GDN) (Peptidase inhibitor 7) (PI-7) (Protease nexin 1) (PN-1) (Protease nexin I) (Serpin E2)SERPINE2 PI7 PN1P07093132
NADH-cytochrome b5 reductase 3 (B5R) (Cytochrome b5 reductase) (EC (Diaphorase-1) [Cleaved into: NADH-cytochrome b5 reductase 3 membrane-bound form; NADH-cytochrome b5 reductase 3 soluble form]CYB5R3 DIA1P00387132
Profilin-2 (Profilin II)PFN2P35080132
Protein S100-A16 (Aging-associated gene 13 protein) (Protein S100-F) (S100 calcium-binding protein A16)S100A16 S100F AAG13Q96FQ6132
Scavenger receptor class B member 1 (SRB1) (CD36 and LIMPII analogous 1) (CLA-1) (CD36 antigen-like 1) (Collagen type I receptor, thrombospondin receptor-like 1) (SR-BI) (CD antigen CD36)SCARB1 CD36L1 CLA1Q8WTV0132
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)SRSF1 ASF SF2 SF2P33 SFRS1 OK/SW-cl.3Q07955132
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