EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial (Complex I-KFYI) (CI-KFYI) (NADH-ubiquinone oxidoreductase KFYI subunit)Ndufc1Q9CQY912
Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein)NfiaQ0278012
Nucleoporin GLE1 (GLE1-like protein)Gle1 Gle1lQ8R32212
Nucleosome assembly protein 1-like 1 (Brain protein DN38) (NAP-1-related protein)Nap1l1 NrpP2865612
Peroxisomal membrane protein 11A (Peroxin-11A) (Peroxisomal biogenesis factor 11A) (Protein PEX11 homolog alpha) (PEX11-alpha)Pex11aQ9Z21112
Protein quaking (MqkI) (qkI)Qki Qk Qk1 Qka1Q9QYS912
Serine incorporator 3 (Axotomy-induced glyco/Golgi protein 1) (AIGP-1) (Axotomy-induced glycoprotein 1) (Membrane protein TMS-1) (Tumor differentially expressed protein 1)Serinc3 Aigp1 Diff33 Tde1 Tms1Q9QZI912
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha)Ppp2r1aQ76MZ312
Signal recognition particle 9 kDa protein (SRP9)Srp9P4996212
Transmembrane emp24 domain-containing protein 2 (COPI-coated vesicle membrane protein p24) (Membrane protein p24A) (Sid 394) (p24 family protein beta-1) (p24beta1)Tmed2 Rnp24 Sid394Q9R0Q312
Tyrosine-protein phosphatase non-receptor type 11 (EC (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2)Ptpn11P3523512
UHRF1-binding protein 1-likeUhrf1bp1l Kiaa0701A2RSJ412
Uncharacterized protein C1orf43 homolog0Q8R09212
Vascular endothelial growth factor A (VEGF-A) (Vascular permeability factor) (VPF)Vegfa VegfQ0073112
40S ribosomal protein S13Rps13P6230111
40S ribosomal protein S15 (RIG protein)Rps15 RigP6284311
60S ribosomal protein L29Rpl29 Rpl43P4791511
60S ribosomal protein L37aRpl37aP6151411
Abl interactor 2 (Abelson interactor 2) (Abi-2)Abi2P6248411
Acyl carrier protein, mitochondrial (ACP) (CI-SDAP) (NADH-ubiquinone oxidoreductase 9.6 kDa subunit)Ndufab1Q9CR2111
BET1-like protein (Golgi SNARE with a size of 15 kDa) (GOS-15) (GS15) (Vesicle transport protein GOS15)Bet1l Gs15O3515311
Caspase-3 (CASP-3) (EC (Apopain) (Cysteine protease CPP32) (CPP-32) (LICE) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]Casp3 Cpp32P7067711
Cell division cycle 5-like protein (Cdc5-like protein)Cdc5l Kiaa0432Q6A06811
Clathrin light chain A (Clathrin, light polypeptide (Lca), isoform CRA_c)Clta mCG_16456B1AWD811
Coactosin-like proteinCotl1 ClpQ9CQI611
Collagen alpha-1(I) chain (Alpha-1 type I collagen)Col1a1 Cola1P1108711
Cytochrome c oxidase subunit 5B, mitochondrial (Cytochrome c oxidase, subunit Vb) (MCG17741, isoform CRA_d) (MCG23026) (Protein Gm11273)Cox5b Gm11273 mCG_17741 mCG_23026Q9D88111
DnaJ homolog subfamily C member 11Dnajc11Q5U45811
E3 SUMO-protein ligase EGR2 (EC 6.3.2.-) (Early growth response protein 2) (EGR-2) (Zinc finger protein Krox-20)Egr2 Egr-2 Krox-20 Zfp-25P0815211
Elongation factor 2 (EF-2)Eef2P5825211
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)Eif3i Eif3s2 Trip1Q9QZD911
Fibronectin (FN) [Cleaved into: Anastellin]Fn1P1127611
GTP-binding protein 2 (GTP-binding-like protein 2)Gtpbp2Q3UJK411
H-2 class I histocompatibility antigen, D-B alpha chain (H-2D(B))H2-D1P0189911
HBS1-like proteinHbs1l Hbs1 Kiaa1038Q69ZS711
Insulin-induced gene 2 protein (INSIG-2)Insig2Q91WG111
Insulin-like growth factor I (IGF-I) (Somatomedin)Igf1 Igf-1P0501711
Insulin-like growth factor II (IGF-II) (Multiplication-stimulating polypeptide) [Cleaved into: Insulin-like growth factor II; Preptin]Igf2 Igf-2P0953511
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68)Khdrbs1Q6074911
Kinesin-1 heavy chain (Conventional kinesin heavy chain) (Ubiquitous kinesin heavy chain) (UKHC)Kif5b Khcs Kns1Q6176811
Kinesin-like protein KIF1BKif1bQ6057511
LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)Lasp1 Mln50Q6179211
Lipoma-preferred partner homologLppQ8BFW711
Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (MNK1) (Microtubule-associated protein 2 kinase) (p44-ERK1)Mapk3 Erk1 Prkm3Q6384411
Mitogen-activated protein kinase kinase kinase 12 (EC (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)Map3k12 ZpkQ6070011
Myeloid differentiation primary response protein MyD88Myd88P2236611
NHL repeat-containing protein 2Nhlrc2Q8BZW811
Non-specific lipid-transfer protein (NSL-TP) (EC (Propanoyl-CoA C-acyltransferase) (SCP-chi) (SCPX) (Sterol carrier protein 2) (SCP-2) (Sterol carrier protein X) (SCP-X)Scp2 Scp-2P3202011
Nuclear factor 1 B-type (NF1-B) (Nuclear factor 1/B) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/B) (NF-I/B) (NFI-B) (TGGCA-binding protein)NfibP9786311
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (NF-kappa-B1 p84/NF-kappa-B1 p98) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]Nfkb1P2579911
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)Pabpc1 Pabp1P2934111
Porphobilinogen deaminase (PBG-D) (EC (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase)Hmbs Uros1P2290711
Pre-mRNA-processing factor 19 (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (Senescence evasion factor)Prpf19 Prp19 SnevQ99KP611
Prelamin-A/C [Cleaved into: Lamin-A/C]Lmna Lmn1P4867811
Protein angel homolog 2Angel2 D1Ertd396e D1Ertd654e MNCb-4273Q8K1C011
Protein CBFA2T1 (Protein MTG8)Runx1t1 Cbfa2t1 Cbfa2t1h Mtg8Q6190911
Protein phosphatase 1A (EC (Protein phosphatase 2C isoform alpha) (PP2C-alpha) (Protein phosphatase IA)Ppm1a Pppm1aP4944311
Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2)G3bp2P9737911
RecQ-mediated genome instability protein 1Rmi1Q9D4G911
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC Ppp1aP6213711
Signal transducer and transcription activator 6Stat6P5263311
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (EC (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s)Oxct1 Oxct ScotQ9D0K211
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)Rela Nfkb3Q0420711
Transmembrane 9 superfamily member 1Tm9sf1Q9DBU011
Tyrosine-protein phosphatase non-receptor type 12 (EC (MPTP-PEST) (Protein-tyrosine phosphatase P19) (P19-PTP)Ptpn12P3583111
28S ribosomal protein S29, mitochondrial (MRP-S29) (S29mt) (Death-associated protein 3) (DAP-3)Dap3 Mrps29Q9ER8810
40S ribosomal protein S29Rps29P6227410
40S ribosomal protein S8Rps8P6224210
60S ribosomal protein L22 (Heparin-binding protein HBp15)Rpl22P6798410
60S ribosomal protein L9Rpl9P5141010
Acyl-CoA-binding protein (ACBP) (Diazepam-binding inhibitor) (DBI) (Endozepine) (EP)DbiP3178610
Amyloid beta A4 protein (ABPP) (APP) (Alzheimer disease amyloid A4 protein homolog) (Amyloidogenic glycoprotein) (AG) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (APP-C59) (Amyloid intracellular domain 59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (APP-C57) (Amyloid intracellular domain 57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AID(50)) (Gamma-CTF(50)); C31]AppP1202310
Annexin A8 (Annexin VIII) (Annexin-8)Anxa8 Anx8O3564010
Apolipoprotein E (Apo-E)ApoeP0822610
Apoptosis regulator BAXBaxQ0781310
Aspartyl aminopeptidase (EC
ATM interactor (ATM/ATR-substrate CHK2-interacting zinc finger protein) (ASCIZ)Atmin Kiaa0431Q6P9S110
ATP synthase subunit d, mitochondrial (ATPase subunit d)Atp5hQ9DCX210
ATP synthase-coupling factor 6, mitochondrial (ATPase subunit F6)Atp5jP9745010
Bteb1 protein (Klf9 protein) (Krueppel-like factor 9) (Kruppel-like factor 9)Klf9 Bteb1 mCG_5314Q8CEC410
C-C chemokine receptor type 9 (C-C CKR-9) (CC-CKR-9) (CCR-9) (Chemokine C-C receptor 10) (CD antigen CDw199)Ccr9 Cmkbr10Q9WUT710
C-C motif chemokine 2 (Monocyte chemoattractant protein 1) (Monocyte chemotactic protein 1) (MCP-1) (Platelet-derived growth factor-inducible protein JE) (Small-inducible cytokine A2)Ccl2 Je Mcp1 Scya2P1014810
Casein kinase 1, alpha 1 (Casein kinase 1, alpha 1, isoform CRA_a)Csnk1a1 mCG_12653Q6PJ8710
Citrate synthase, mitochondrial (EC
Collagen alpha-1(II) chain (Alpha-1 type II collagen) [Cleaved into: Collagen alpha-1(II) chain; Chondrocalcin]Col2a1P2848110
Complement C3 (HSE-MSF) [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Acylation stimulating protein (ASP) (C3adesArg); Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2]C3P0102710
CUGBP Elav-like family member 1 (CELF-1) (50 kDa nuclear polyadenylated RNA-binding protein) (Brain protein F41) (Bruno-like protein 2) (CUG triplet repeat RNA-binding protein 1) (CUG-BP1) (CUG-BP- and ETR-3-like factor 1) (Deadenylation factor CUG-BP) (Deadenylation factor EDEN-BP) (Embryo deadenylation element-binding protein homolog) (EDEN-BP homolog) (RNA-binding protein BRUNOL-2)Celf1 Brunol2 Cugbp Cugbp1P2865910
Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4a) (p16-INK4)Cdkn2a P16ink4aP5148010
Cytochrome c oxidase subunit 6B1 (Cytochrome c oxidase subunit VIb isoform 1) (COX VIb-1)Cox6b1 Cox6bP5639110
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC (p460)Prkdc Xrcc7P9731310
Dynactin subunit 2 (50 kDa dynein-associated polypeptide) (Dynactin complex 50 kDa subunit) (DCTN-50) (Growth cone membrane protein 23-48K) (GMP23-48K) (p50 dynamitin)Dctn2Q99KJ810
Eukaryotic translation initiation factor 3 subunit E (eIF3e) (Eukaryotic translation initiation factor 3 subunit 6) (MMTV integration site 6) (Mammary tumor-associated protein INT-6) (Viral integration site protein INT-6) (eIF-3 p48)Eif3e Eif3s6 Int6P6022910
Fibroblast growth factor 10 (FGF-10) (Keratinocyte growth factor 2)Fgf10O3556510
Gamma-secretase subunit APH-1A (APH-1a) (Aph-1alpha)Aph1aQ8BVF710
Glutathione S-transferase A4 (EC (GST A4-4) (GSTA4-4) (GST class-alpha member 4) (Glutathione S-transferase 5.7) (GST 5.7)Gsta4 GstaP2447210
Guanidinoacetate N-methyltransferase (EC
Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8)Hspa8 Hsc70 Hsc73P6301710
Hematological and neurological expressed 1 protein [Cleaved into: Hematological and neurological expressed 1 protein, N-terminally processed]Hn1P9782510
Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (CArG-binding factor-A) (CBF-A)Hnrnpab Cbf-a Cgbfa HnrpabQ9902010
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (HDP-1) (Helix-destabilizing protein) (Single-strand-binding protein) (Topoisomerase-inhibitor suppressed) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]Hnrnpa1 Fli-2 Hnrpa1 TisP4931210
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