EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
Cullin-1 (CUL-1)CUL1Q1361682
DNA replication licensing factor MCM6 (EC (p105MCM)MCM6Q1456682
Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]HNRNPH2 FTP3 HNRPH2P5579582
Integrin alpha-1 (CD49 antigen-like family member A) (Laminin and collagen receptor) (VLA-1) (CD antigen CD49a)ITGA1P5619982
Integrin alpha-IIb (GPalpha IIb) (GPIIb) (Platelet membrane glycoprotein IIb) (CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2]ITGA2B GP2B ITGABP0851482
Niemann-Pick C1 proteinNPC1O1511882
Nuclear protein localization protein 4 homolog (Protein NPL4)NPLOC4 KIAA1499 NPL4Q8TAT682
Prefoldin subunit 1PFDN1 PFD1O6092582
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (EC (Lysyl hydroxylase 2) (LH2)PLOD2O0046982
Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog)SUGT1Q9Y2Z082
Reticulocalbin-1RCN1 RCNQ1529382
Retinoid-inducible serine carboxypeptidase (EC 3.4.16.-) (Serine carboxypeptidase 1)SCPEP1 RISC SCP1 MSTP034 UNQ265/PRO302Q9HB4082
SH3 domain-binding protein 4 (EH-binding protein 10) (Transferrin receptor-trafficking protein)SH3BP4 BOG25 EHB10 TTPQ9P0V382
Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter) (Solute carrier family 5 member 6)SLC5A6 SMVTQ9Y28982
Tax1-binding protein 3 (Glutaminase-interacting protein 3) (Tax interaction protein 1) (TIP-1) (Tax-interacting protein 1)TAX1BP3 TIP1O1490782
Zyxin (Zyxin-2)ZYXQ1594282
Actin, aortic smooth muscle (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein)ACTA2 ACTSA ACTVS GIG46P6273681
ADP-ribosylation factor-like protein 8A (ADP-ribosylation factor-like protein 10B) (Novel small G protein indispensable for equal chromosome segregation 2)ARL8A ARL10B GIE2Q96BM981
Calponin-3 (Calponin, acidic isoform)CNN3Q1541781
Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2)EEA1 ZFYVE2Q1507581
Fumarylacetoacetase (FAA) (EC (Beta-diketonase) (Fumarylacetoacetate hydrolase)FAHP1693081
HLA class I histocompatibility antigen, Cw-7 alpha chain (MHC class I antigen Cw*7)HLA-C HLACP1032181
Katanin p60 ATPase-containing subunit A-like 2 (Katanin p60 subunit A-like 2) (EC (p60 katanin-like 2)KATNAL2Q8IYT481
Kinesin-like protein KIF14KIF14 KIAA0042Q1505881
Protein unc-45 homolog A (Unc-45A) (GCUNC-45) (Smooth muscle cell-associated protein 1) (SMAP-1)UNC45A SMAP1Q9H3U181
Ras-related protein Rab-27A (Rab-27) (GTP-binding protein Ram)RAB27A RAB27P5115981
Ras-related protein Rab-32RAB32Q1363781
Septin-8SEPT8 KIAA0202Q9259981
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)SRSF6 SFRS6 SRP55Q1324781
Serine/threonine-protein kinase TAO1 (EC (Kinase from chicken homolog B) (hKFC-B) (MARK Kinase) (MARKK) (Prostate-derived sterile 20-like kinase 2) (PSK-2) (PSK2) (Prostate-derived STE20-like kinase 2) (Thousand and one amino acid protein kinase 1) (TAOK1) (hTAOK1)TAOK1 KIAA1361 MAP3K16 MARKKQ7L7X381
Sorting nexin-5SNX5Q9Y5X381
Splicing factor 3B subunit 6 (Pre-mRNA branch site protein p14) (SF3b 14 kDa subunit) (SF3B14a) (Spliceosome-associated protein, 14-kDa) (Splicing factor 3b, subunit 6, 14kDa)SF3B6 SAP14 SF3B14 SF3B14A CGI-110 HSPC175 HT006Q9Y3B481
Tyrosine-protein phosphatase non-receptor type 11 (EC (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3)PTPN11 PTP2C SHPTP2Q0612481
U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (Small nuclear ribonuclear protein D homolog) (snRNP core Sm-like protein Sm-x5)LSM2 C6orf28 G7BQ9Y33381
Ubiquitin carboxyl-terminal hydrolase 7 (EC (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)USP7 HAUSPQ9300981
Vesicle-associated membrane protein 7 (VAMP-7) (Synaptobrevin-like protein 1) (Tetanus-insensitive VAMP) (Ti-VAMP)VAMP7 SYBL1P5180981
5'-AMP-activated protein kinase subunit gamma-1 (AMPK gamma1) (AMPK subunit gamma-1) (AMPKg)PRKAG1P5461980
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)COPS2 CSN2 TRIP15P6120180
Cullin-3 (CUL-3)CUL3 KIAA0617Q1361880
Cystatin-A (Cystatin-AS) (Stefin-A) [Cleaved into: Cystatin-A, N-terminally processed]CSTA STF1 STFAP0104080
Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va)COX5AP2067480
Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic) (LIC-2) (LIC53/55)DYNC1LI2 DNCLI2 LIC2O4323780
Fibrillin-1 [Cleaved into: Asprosin]FBN1 FBNP3555580
Ganglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Sphingolipid activator protein 3) (SAP-3) [Cleaved into: Ganglioside GM2 activator isoform short]GM2AP1790080
Immunoglobulin heavy constant gamma 3 (HDC) (Heavy chain disease protein) (Ig gamma-3 chain C region)IGHG3P0186080
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)IGF2BP3 IMP3 KOC1 VICKZ3O0042580
Mannan-binding lectin serine protease 1 (EC 3.4.21.-) (Complement factor MASP-3) (Complement-activating component of Ra-reactive factor) (Mannose-binding lectin-associated serine protease 1) (MASP-1) (Mannose-binding protein-associated serine protease) (Ra-reactive factor serine protease p100) (RaRF) (Serine protease 5) [Cleaved into: Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain]MASP1 CRARF CRARF1 PRSS5P4874080
Protein CYR61 (CCN family member 1) (Cysteine-rich angiogenic inducer 61) (Insulin-like growth factor-binding protein 10) (IBP-10) (IGF-binding protein 10) (IGFBP-10) (Protein GIG1)CYR61 CCN1 GIG1 IGFBP10O0062280
Protein FAM234A (Protein ITFG3)FAM234A C16orf9 ITFG3Q9H0X480
Protein NDRG3 (N-myc downstream-regulated gene 3 protein)NDRG3Q9UGV280
Protein tyrosine phosphatase type IVA 1 (EC (PTP(CAAXI)) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1)PTP4A1 PRL1 PTPCAAX1Q9309680
Pterin-4-alpha-carbinolamine dehydratase (PHS) (EC (4-alpha-hydroxy-tetrahydropterin dehydratase) (Dimerization cofactor of hepatocyte nuclear factor 1-alpha) (DCoH) (Dimerization cofactor of HNF1) (Phenylalanine hydroxylase-stimulating protein) (Pterin carbinolamine dehydratase) (PCD)PCBD1 DCOH PCBDP6145780
Ras-related protein Rab-3BRAB3BP2033780
RNA-binding protein Raly (Autoantigen p542) (Heterogeneous nuclear ribonucleoprotein C-like 2) (hnRNP core protein C-like 2) (hnRNP associated with lethal yellow protein homolog)RALY HNRPCL2 P542Q9UKM980
Transmembrane 9 superfamily member 2 (p76)TM9SF2Q9980580
Vacuolar-sorting protein SNF8 (ELL-associated protein of 30 kDa) (ESCRT-II complex subunit VPS22) (hVps22)SNF8 EAP30Q96H2080
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)VAMP2 SYB2P6302780
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (EC (Phosphoinositide phospholipase C-beta-3) (Phospholipase C-beta-3) (PLC-beta-3)PLCB3Q0197079
Carboxymethylenebutenolidase homolog (EC 3.1.-.-)CMBLQ96DG679
CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1) (Negative regulator of transcription subunit 1 homolog) (NOT1H) (hNOT1)CNOT1 CDC39 KIAA1007 NOT1 AD-005A5YKK679
Citron Rho-interacting kinase (CRIK) (EC (Serine/threonine-protein kinase 21)CIT CRIK KIAA0949 STK21O1457879
Cold shock domain-containing protein E1 (N-ras upstream gene protein) (Protein UNR)CSDE1 D1S155E KIAA0885 NRU UNRO7553479
Cysteine-rich protein 2 (CRP-2) (Protein ESP1)CRIP2 CRP2P5294379
Cytoskeleton-associated protein 5 (Colonic and hepatic tumor overexpressed gene protein) (Ch-TOG)CKAP5 KIAA0097Q1400879
IgGFc-binding protein (Fcgamma-binding protein antigen) (FcgammaBP)FCGBPQ9Y6R779
Lymphocyte function-associated antigen 3 (Ag3) (Surface glycoprotein LFA-3) (CD antigen CD58)CD58 LFA3P1925679
Mannose-1-phosphate guanyltransferase beta (EC (GDP-mannose pyrophosphorylase B) (GTP-mannose-1-phosphate guanylyltransferase beta)GMPPBQ9Y5P679
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (NHE3 kinase A regulatory protein E3KARP) (SRY-interacting protein 1) (SIP-1) (Sodium-hydrogen exchanger regulatory factor 2) (Solute carrier family 9 isoform A3 regulatory factor 2) (Tyrosine kinase activator protein 1) (TKA-1)SLC9A3R2 NHERF2Q1559979
PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein)PDLIM5 ENH L9Q96HC479
Peptidyl-prolyl cis-trans isomerase-like 1 (PPIase) (EC (Rotamase PPIL1)PPIL1 CYPL1 CGI-124 UNQ2425/PRO4984Q9Y3C679
Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif)ANKFY1 ANKHZN KIAA1255Q9P2R379
Rho-related GTP-binding protein RhoF (Rho family GTPase Rif) (Rho in filopodia)RHOF ARHF RIFQ9HBH079
Signal recognition particle 9 kDa protein (SRP9)SRP9P4945879
Thrombospondin-2THBS2 TSP2P3544279
Transmembrane emp24 domain-containing protein 7 (p24 family protein gamma-3) (p24gamma3) (p27)TMED7 CGI-109Q9Y3B379
3-hydroxybutyrate dehydrogenase type 2 (EC 1.1.1.-) (EC (Dehydrogenase/reductase SDR family member 6) (Oxidoreductase UCPA) (R-beta-hydroxybutyrate dehydrogenase) (Short chain dehydrogenase/reductase family 15C member 1)BDH2 DHRS6 SDR15C1 UNQ6308/PRO20933Q9BUT178
ATP synthase F(0) complex subunit B1, mitochondrial (ATP synthase proton-transporting mitochondrial F(0) complex subunit B1) (ATP synthase subunit b) (ATPase subunit b)ATP5F1P2453978
COMM domain-containing protein 3 (Protein Bup) (Protein PIL)COMMD3 BUP C10orf8Q9UBI178
Cyclin-Y (Cyc-Y) (Cyclin box protein 1) (Cyclin fold protein 1) (cyclin-X)CCNY C10orf9 CBCP1 CFP1Q8ND7678
Delta-1-pyrroline-5-carboxylate synthase (P5CS) (Aldehyde dehydrogenase family 18 member A1) [Includes: Glutamate 5-kinase (GK) (EC (Gamma-glutamyl kinase); Gamma-glutamyl phosphate reductase (GPR) (EC (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)]ALDH18A1 GSAS P5CS PYCSP5488678
Dihydropyrimidinase-related protein 3 (DRP-3) (Collapsin response mediator protein 4) (CRMP-4) (Unc-33-like phosphoprotein 1) (ULIP-1)DPYSL3 CRMP4 DRP3 ULIP ULIP1Q1419578
Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)MAP2K2 MEK2 MKK2 PRKMK2P3650778
Eukaryotic translation initiation factor 1 (eIF1) (A121) (Protein translation factor SUI1 homolog) (Sui1iso1)EIF1 SUI1P4156778
Kinesin light chain 1 (KLC 1)KLC1 KLC KNS2Q0786678
Methylosome protein 50 (MEP-50) (Androgen receptor cofactor p44) (WD repeat-containing protein 77) (p44/Mep50)WDR77 MEP50 WD45 HKMT1069 Nbla10071Q9BQA178
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC (Peptidyl-prolyl cis-trans isomerase Pin1) (PPIase Pin1) (Rotamase Pin1)PIN1Q1352678
Proteasome subunit beta type-9 (EC (Low molecular mass protein 2) (Macropain chain 7) (Multicatalytic endopeptidase complex chain 7) (Proteasome chain 7) (Proteasome subunit beta-1i) (Really interesting new gene 12 protein)PSMB9 LMP2 PSMB6i RING12P2806578
Protein 4.1 (P4.1) (4.1R) (Band 4.1) (EPB4.1)EPB41 E41PP1117178
Selenium-binding protein 1 (56 kDa selenium-binding protein) (SBP56) (SP56)SELENBP1 SBPQ1322878
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)SRSF10 FUSIP1 FUSIP2 SFRS13A TASRO7549478
U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A)SNRPAP0901278
Urokinase plasminogen activator surface receptor (U-PAR) (uPAR) (Monocyte activation antigen Mo3) (CD antigen CD87)PLAUR MO3 UPARQ0340578
72 kDa type IV collagenase (EC (72 kDa gelatinase) (Gelatinase A) (Matrix metalloproteinase-2) (MMP-2) (TBE-1) [Cleaved into: PEX]MMP2 CLG4AP0825377
Arginase-1 (EC (Liver-type arginase) (Type I arginase)ARG1P0508977
Bone morphogenetic protein 1 (BMP-1) (EC (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP)BMP1 PCOLCP1349777
Cytochrome b reductase 1 (EC 1.-.-.-) (Duodenal cytochrome b) (Ferric-chelate reductase 3)CYBRD1 DCYTB FRRS3Q53TN477
E3 ubiquitin-protein ligase RNF213 (EC (EC 3.6.4.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213) (RING-type E3 ubiquitin transferase RNF213)RNF213 ALO17 C17orf27 KIAA1554 KIAA1618 MYSTRQ63HN877
H/ACA ribonucleoprotein complex subunit 4 (EC 5.4.99.-) (CBF5 homolog) (Dyskerin) (Nopp140-associated protein of 57 kDa) (Nucleolar protein NAP57) (Nucleolar protein family A member 4) (snoRNP protein DKC1)DKC1 NOLA4O6083277
Histone H2A.Z (H2A/z)H2AFZ H2AZP0C0S577
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