EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


The downloaded CSV file is not exactly the same as the displayed table. Opening CSV file with Excel can impair its content.

Protein name Gene symbol UniProt accession Identification number
Neuronal proto-oncogene tyrosine-protein kinase Src (EC (Proto-oncogene c-Src) (pp60c-src) (p60-Src)SrcP0548014
Nucleolar RNA helicase 2 (EC (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)Ddx21Q9JIK514
PDZ domain-containing protein GIPC1 (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (RGS19-interacting protein 1) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1) (Synectin)Gipc1 Gipc Rgs19ip1 Semcap1Q9Z0G014
Periostin (PN) (Osteoblast-specific factor 2) (OSF-2)Postn Osf2Q6200914
Plasminogen activator inhibitor 1 RNA-binding protein (PAI1 RNA-binding protein 1) (PAI-RBP1) (SERPINE1 mRNA-binding protein 1)Serbp1 Pairbp1Q9CY5814
Platelet glycoprotein 4 (Glycoprotein IIIb) (GPIIIB) (PAS IV) (PAS-4) (Platelet glycoprotein IV) (GPIV) (CD antigen CD36)Cd36Q0885714
Proteasome activator complex subunit 1 (11S regulator complex subunit alpha) (REG-alpha) (Activator of multicatalytic protease subunit 1) (Proteasome activator 28 subunit alpha) (PA28a) (PA28alpha)Psme1P9737114
Proteasome activator complex subunit 2 (11S regulator complex subunit beta) (REG-beta) (Activator of multicatalytic protease subunit 2) (Proteasome activator 28 subunit beta) (PA28b) (PA28beta)Psme2 Pa28b1P9737214
Protein EFR3 homolog A (Protein EFR3-like)Efr3a Kiaa0143Q8BG6714
Protein scribble homolog (Scribble) (Protein LAP4)Scrib Kiaa0147 Lap4 Scrib1Q80U7214
Pyridoxal kinase (EC (Pyridoxine kinase)Pdxk PkhQ8K18314
Rac GTPase-activating protein 1 (Male germ cell RacGap) (MgcRacGAP)Racgap1 MgcracgapQ9WVM114
Ras-related GTP-binding protein A (Rag A) (RagA)RragaQ80X9514
Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC PtpkP3582214
Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC (PTPNU-3) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma)PtprsB0V2N114
Serine hydroxymethyltransferase (EC
Serine hydroxymethyltransferase, cytosolic (SHMT) (EC (Glycine hydroxymethyltransferase) (Serine methylase)Shmt1 ShmtP5043114
Serine/threonine-protein kinase TAO1 (EC (Thousand and one amino acid protein 1)Taok1 Kiaa1361Q5F2E814
Solute carrier family 2, facilitated glucose transporter member 3 (Glucose transporter type 3, brain) (GLUT-3)Slc2a3 Glut-3 Glut3P3203714
Sorting nexin-2Snx2Q9CWK814
Sorting nexin-5Snx5Q9D8U814
Splicing factor 3B subunit 4Sf3b4Q8QZY914
Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Chromosome segregation protein SmcB) (Sb1.8)Smc1a Sb1.8 Smc1 Smc1l1 SmcbQ9CU6214
Structural maintenance of chromosomes protein 4 (SMC protein 4) (SMC-4) (Chromosome-associated polypeptide C) (XCAP-C homolog)Smc4 Capc Smc4l1Q8CG4714
Syntaxin-binding protein 1 (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A)Stxbp1O0859914
Tenascin (TN) (Hexabrachion) (Tenascin-C) (TN-C)Tnc HxbQ80YX114
Transmembrane 9 superfamily member 3Tm9sf3 SmbpQ9ET3014
Tubulin beta-4A chain (Tubulin beta-4 chain)Tubb4a Tubb4Q9D6F914
Tubulointerstitial nephritis antigen-like (Adrenocortical zonation factor 1) (AZ-1) (Androgen-regulated gene 1 protein) (Tubulointerstitial nephritis antigen-related protein) (TARP)Tinagl1 Arg1 Lcn7 TinaglQ99JR514
Twinfilin-2 (A6-related protein) (mA6RP) (Twinfilin-1-like protein)Twf2 Ptk9lQ9Z0P514
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)Snrnp70 Snrp70Q6237614
Ubiquitin carboxyl-terminal hydrolase 15 (EC (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15)Usp15 Kiaa0529Q8R5H114
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (mAGP7) (Ubiquitin-activating enzyme E1-like protein)Atg7 Apg7lQ9D90614
UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC
3-ketoacyl-CoA thiolase A, peroxisomal (EC (Acetyl-CoA acyltransferase A) (Beta-ketothiolase A) (Peroxisomal 3-oxoacyl-CoA thiolase A)Acaa1a Acaa1Q921H813
3-ketoacyl-CoA thiolase, mitochondrial (EC (Acetyl-CoA acyltransferase) (Beta-ketothiolase) (Mitochondrial 3-oxoacyl-CoA thiolase)Acaa2Q8BWT113
40S ribosomal protein S15 (RIG protein)Rps15 RigP6284313
60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (TROVE domain family member 2)Trove2 Ssa2O0884813
60S ribosomal protein L10a (CSA-19) (Neural precursor cell expressed developmentally down-regulated protein 6) (NEDD-6)Rpl10a Nedd-6 Nedd6P5302613
Actin, aortic smooth muscle (Alpha-actin-2)Acta2 Actsa ActvsP6273713
Acylamino-acid-releasing enzyme (AARE) (EC (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase)ApehQ8R14613
ADP-ribosylation factor 2Arf2Q8BSL713
ADP-ribosylation factor-like protein 1Arl1P6121113
Alpha-2-HS-glycoprotein (Countertrypin) (Fetuin-A)Ahsg FetuaP2969913
Amino acid transporterSlc1a5 mCG_2082Q9ESU713
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43) [Cleaved into: Endothelial monocyte-activating polypeptide 2 (EMAP-2) (Endothelial monocyte-activating polypeptide II) (EMAP-II) (Small inducible cytokine subfamily E member 1)]Aimp1 Emap2 Scye1P3123013
AP-1 complex subunit mu-1 (AP-mu chain family member mu1A) (Adaptor protein complex AP-1 subunit mu-1) (Adaptor-related protein complex 1 subunit mu-1) (Clathrin assembly protein complex 1 mu-1 medium chain 1) (Clathrin coat assembly protein AP47) (Clathrin coat-associated protein AP47) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Mu-adaptin 1) (Mu1A-adaptin)Ap1m1 CltnmP3558513
AP-3 complex subunit beta-1 (Adaptor protein complex AP-3 subunit beta-1) (Adaptor-related protein complex 3 subunit beta-1) (Beta-3A-adaptin) (Clathrin assembly protein complex 3 beta-1 large chain)Ap3b1Q9Z1T113
Apoptosis regulator BAXBaxQ0781313
C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-)Ctbp1O8871213
Calcineurin B homologous protein 1 (Calcineurin B-like protein) (Calcium-binding protein CHP) (Calcium-binding protein p22) (EF-hand calcium-binding domain-containing protein p22) (Sid 470) (p24)Chp1 Chp Sid470P6102213
Calcyclin-binding protein (CacyBP) (Siah-interacting protein)Cacybp SipQ9CXW313
Caprin-1 (Cytoplasmic activation- and proliferation-associated protein 1) (GPI-anchored membrane protein 1) (GPI-anchored protein p137) (GPI-p137) (p137GPI) (Membrane component chromosome 11 surface marker 1) (RNA granule protein 105)Caprin1 Gpiap Gpiap1 Gpip137 M11s1 Rng105 G5E5Q6086513
Caspase-3 (CASP-3) (EC (Apopain) (Cysteine protease CPP32) (CPP-32) (LICE) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]Casp3 Cpp32P7067713
Caveolin-1Cav1 CavP4981713
CD109 antigen (GPI-anchored alpha-2 macroglobulin-related protein) (CD antigen CD109)Cd109Q8R42213
Charged multivesicular body protein 6 (Chromatin-modifying protein 6)Chmp6P0C0A313
Coiled-coil and C2 domain-containing protein 1A (Five prime repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1)Cc2d1aQ8K1A613
Complement C1s-A subcomponent (EC (C1 esterase) (Complement component 1 subcomponent s-A) [Cleaved into: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain]C1sa C1sQ8CG1413
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (Cytochrome c oxidase polypeptide IV) (Cytochrome c oxidase subunit IV isoform 1) (COX IV-1)Cox4i1 Cox4 Cox4aP1978313
Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va)Cox5aP1278713
Delta-aminolevulinic acid dehydratase (ALADH) (EC (Porphobilinogen synthase)Alad LvP1051813
Developmentally-regulated GTP-binding protein 2 (DRG-2)Drg2Q9QXB913
Disintegrin and metalloproteinase domain-containing protein 9 (ADAM 9) (EC 3.4.24.-) (Meltrin-gamma) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase)Adam9 Kiaa0021 Mdc9 MltngQ6107213
DNA replication licensing factor MCM2 (EC (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)Mcm2 Bm28 Cdcl1 Kiaa0030 Mcmd2P9731013
DNA replication licensing factor MCM4 (EC (CDC21 homolog) (P1-CDC21)Mcm4 Cdc21 Mcmd4P4971713
DNA replication licensing factor MCM6 (EC (Mis5 homolog)Mcm6 Mcmd6 Mis5P9731113
E3 ubiquitin-protein ligase RNF213 (EC (EC 3.6.4.-) (Mysterin) (RING finger protein 213) (RING-type E3 ubiquitin transferase RNF213)Rnf213 MystrE9Q55513
E3 ubiquitin-protein ligase TRIP12 (EC (HECT-type E3 ubiquitin transferase TRIP12) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12)Trip12G5E87013
Elongation factor Tu, mitochondrialTufmQ8BFR513
Elongin-C (EloC) (Elongin 15 kDa subunit) (RNA polymerase II transcription factor SIII subunit C) (SIII p15) (Stromal membrane-associated protein SMAP1B homolog) (Transcription elongation factor B polypeptide 1)Eloc Tceb1P8394013
Ephrin-B1 (CEK5 receptor ligand) (CEK5-L) (ELK ligand) (ELK-L) (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) (Stimulated by retinoic acid gene 1 protein)Efnb1 Epl2 Eplg2 Lerk2 Stra1P5279513
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a) (eRF3a) (G1 to S phase transition protein 1 homolog)Gspt1 Erf3aQ8R05013
Formin-like protein 2 (Protein Man)Fmnl2 Kiaa1902 ManA2APV213
Fructose-bisphosphate aldolase (EC mCG_22383A6ZI4413
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC (Serine/threonine-protein kinase GSK3B) (EC
GMP synthase [glutamine-hydrolyzing] (EC (GMP synthetase) (Glutamine amidotransferase)GmpsQ3THK713
Golgi apparatus protein 1 (E-selectin ligand 1) (ESL-1) (Selel) (Golgi sialoglycoprotein MG-160)Glg1 Esl1 Mg160 SelelQ6154313
GTPase NRas (Transforming protein N-Ras)NrasP0855613
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (Adenylate cyclase-stimulating G alpha protein)Gnas Gnas1 MNCb-5546P6309413
H/ACA ribonucleoprotein complex subunit 4 (EC 5.4.99.-) (Dyskerin) (Nopp140-associated protein of 57 kDa) (Nucleolar protein NAP57) (Nucleolar protein family A member 4) (snoRNP protein DKC1)Dkc1Q9ESX513
Heat shock 70 kDa protein 1-like (Heat shock 70 kDa protein 1L) (Heat shock 70 kDa-like protein 1) (Spermatid-specific heat shock protein 70)Hspa1l Hsc70tP1662713
HemopexinHpx HpxnQ91X7213
Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0)Hnrnpa0 Hnrpa0Q9CX8613
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (MLF1-associated nuclear protein)Hnrnpul2 Hnrpul2 ManpQ00PI913
Histone deacetylase 1 (HD1) (EC
Histone H2A type 1-FHist1h2afQ8CGP513
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)Rbbp7 Rbap46Q6097313
Ig kappa chain C region0P0183713
Importin-4 (Imp4) (Importin-4a) (Imp4a) (Ran-binding protein 4) (RanBP4)Ipo4 Imp4a Ranbp4Q8VI7513
Inosine triphosphate pyrophosphatase (ITPase) (Inosine triphosphatase) (EC (Non-canonical purine NTP pyrophosphatase) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase)ItpaQ9D89213
Keratin 78Krt78E9Q0F013
Keratin, type II cytoskeletal 71 (Cytokeratin-6G) (CK-6G) (Cytokeratin-71) (CK-71) (Keratin-6G) (K6G) (Keratin-71) (K71) (Type II inner root sheath-specific keratin-K6irs1) (mK6irs) (mK6irs1/Krt2-6g) (Type-II keratin Kb34)Krt71 K6irs1 Kb34 Krt2-6g Krt6gQ9R0H513
Lethal(2) giant larvae protein homolog 1 (LLGL) (Mgl-1) (Mlgl)Llgl1 LlglhQ80Y1713
Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1)Ppfibp1 Kiaa1230Q8C8U013
Lysosomal alpha-glucosidase (EC (Acid maltase)GaaP7069913
Lysosomal alpha-mannosidase (Laman) (EC (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B)Man2b1 Laman Man2b ManbO0915913
MCG124046 (Protease, serine 1 (trypsin 1)) (Protease, serine, 1 (Trypsin 1)) (Trypsinogen 16)Prss1 Trygn16 trypsinogen mCG_124046Q9Z1R913
Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1)Mta2 Mta1l1Q9R19013
MIT domain-containing protein 1Mitd1Q8VDV813
< [12] [13] [14] [15] [16] [17] [18] [19] [20] [21] >