EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Signal peptidase complex catalytic subunit SEC11 (EC 3.4.21.89)Sec11aD3YWT02
Signal peptidase complex catalytic subunit SEC11 (EC 3.4.21.89) (Fragment)Sec11a Sec11l1Q6PET32
Signal peptidase complex subunit 1 (EC 3.4.-.-) (Microsomal signal peptidase 12 kDa subunit) (SPase 12 kDa subunit)Spcs1 Spc12Q9D9582
Signal recognition particle 19 kDa protein (Signal recognition particle 19, isoform CRA_b)Srp19 mCG_121501G5E8T32
Signal recognition particle 19 kDa protein (SRP19)Srp19Q9D7A62
Signal recognition particle 54A (Fragment)Srp54aA0A1W2P8092
Signal transducer and activator of transcriptionStat1A0A087WSP52
Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2)Sipa1l2 Kiaa0545Q80TE42
Signal-induced proliferation-associated 1-like protein 3 (SIPA1-like protein 3) (SPA-1-like protein 3)Sipa1l3 Spal3G3X9J02
Signal-induced proliferation-associated protein 1Sipa1E9Q0Y42
Signal-transducing adaptor protein 1 (STAP-1) (Stem cell adaptor protein 1)Stap1Q9JM902
Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8)Sigirr Tir8Q9JLZ82
Sister chromatid cohesion protein PDS5 homolog APds5aE9QPI52
Sjoegren syndrome/scleroderma autoantigen 1 homolog (Autoantigen p27 homolog) (Protein C184L)Sssca1 C184lP568732
Slc2a6 protein (Solute carrier family 2 (facilitated glucose transporter), member 6)Slc2a6A2AR262
Small membrane A-kinase anchor protein (Small membrane AKAP) (smAKAP)0Q9CPS82
Small nuclear ribonucleoprotein ESnrpeE9Q0W82
Small ubiquitin-related modifier 1 (SUMO-1) (SMT3 homolog 3) (Ubiquitin-homology domain protein PIC1) (Ubiquitin-like protein SMT3C) (Smt3C)Sumo1 Smt3c Smt3h3 Ubl1P631662
Small ubiquitin-related modifier 2 (SUMO-2) (SMT3 homolog 2) (Ubiquitin-like protein SMT3B) (Smt3B)Sumo2 Smt3b Smt3h2P619572
SmoothelinSmtn SmsmoQ921U82
SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski-interacting protein)Snw1 SkiipQ9CSN12
Sodium-coupled neutral amino acid transporter 9 (Solute carrier family 38 member 9)Slc38a9Q8BGD62
Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10)Slc4a10 Kiaa4136 NcbeQ5DTL92
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 (Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 1) (Protein FAM77C)Nkain1 Fam77cQ9D0352
Solute carrier family 12 member 6Slc12a6A2AGJ92
Solute carrier family 22 member 23Slc22a23Q3UHH22
Solute carrier family 35 member D3 (Fringe connection-like protein 1)Slc35d3 Frcl1Q8BGF82
Solute carrier organic anion transporter family member 2A1 (Prostaglandin transporter) (PGT) (Solute carrier family 21 member 2)Slco2a1 Oatp2a1 Slc21a2Q9EPT52
Son of sevenless homolog 2 (SOS-2) (mSOS-2)Sos2Q023842
Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)Sorbs1 Kiaa1296 Sh3d5Q624172
Sorting nexin-14Snx14Q8BHY82
Sorting nexin-25Snx25Q3ZT312
Spermatogenesis-associated protein 7 homologSpata7Q80VP22
Sphingolipid delta(4)-desaturase DES1 (EC 1.14.19.17) (Degenerative spermatocyte homolog 1)Degs1 Degs Des1 MdesO090052
Sphingomyelin phosphodiesterase (EC 3.1.4.12) (Acid sphingomyelinase) (ASMase)Smpd1 AsmQ045192
Sphingosine-1-phosphate lyase 1Sgpl1D6REF72
Splicing factor 1 (CW17) (Mammalian branch point-binding protein) (BBP) (mBBP) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Zinc finger protein 162)Sf1 Zfm1 Zfp162Q642132
Splicing factor 3A subunit 2 (Splicing factor 3a, subunit 2, isoform CRA_b)Sf3a2 mCG_12094G3UVU22
Splicing factor U2AF 65 kDa subunit (U2af2 protein)U2af2Q3KQM42
SR-related CTD-associated factor 4 (Splicing factor, arginine/serine-rich 15)Scaf4 Sfrs15 Srsf15Q6PFF02
StAR-related lipid transfer protein 3 (Protein ES 64) (Protein MLN 64) (START domain-containing protein 3) (StARD3)Stard3 Es64 Mln64Q615422
Stefin-2Stfa2 Stf-2 Stf2P351742
Sterile alpha motif domain-containing protein 9-likeSamd9lE9PX592
Sterol O-acyltransferase 1 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 1) (ACAT-1) (Cholesterol acyltransferase 1)Soat1 AcactQ612632
Stimulator of interferon genes protein (mSTING) (Endoplasmic reticulum interferon stimulator) (ERIS) (Mediator of IRF3 activation) (MMITA) (Transmembrane protein 173)Tmem173 Eris Mita Mpys StingQ3TBT32
Stonin-2 (Stoned B)Ston2 Stn2 StnbQ8BZ602
Stromal interaction molecule 1Stim1 SimP703022
Stromal membrane-associated protein 1Smap1Q91VZ62
Stromelysin-1 (SL-1) (EC 3.4.24.17) (EMS-2) (Matrix metalloproteinase-3) (MMP-3) (Transin-1)Mmp3P288622
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (Integral membrane protein CII-3) (QPs-1) (QPs1)SdhcQ9CZB02
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial (CybS) (CII-4) (QPs3) (Succinate dehydrogenase complex subunit D) (Succinate-ubiquinone oxidoreductase cytochrome b small subunit) (Succinate-ubiquinone reductase membrane anchor subunit)SdhdQ9CXV12
Succinate-semialdehyde dehydrogenase, mitochondrial (EC 1.2.1.24) (Aldehyde dehydrogenase family 5 member A1) (NAD(+)-dependent succinic semialdehyde dehydrogenase)Aldh5a1Q8BWF02
Sulfatase-modifying factor 1 (EC 1.8.99.-) (C-alpha-formylglycine-generating enzyme 1)Sumf1 FgeQ8R0F32
Sulfhydryl oxidase 2 (EC 1.8.3.2) (Quiescin Q6-like protein 1)Qsox2 Qscn6l1Q3TMX72
Sulfide:quinone oxidoreductase, mitochondrial (SQOR) (EC 1.8.5.-)SqrdlQ9R1122
SulfurtransferaseMpstQ3UW662
SUMO-conjugating enzyme UBC9 (Ube2i protein)Ube2iQ8CFZ02
SUN domain-containing protein 2 (Protein unc-84 homolog B) (Sad1/unc-84 protein-like 2)Sun2 Unc84bQ8BJS42
Superkiller viralicidic activity 2-like (S. cerevisiae)Skiv2lQ6NZR52
Supervillin (Archvillin) (p205/p250)SvilQ8K4L32
Suppressor APC domain-containing protein 2 (Protein Ang)Sapcd2Q9D8182
SuprabasinSbsnE9QPB22
Sushi domain-containing protein 6 (Drago)Susd6 Kiaa0247Q8BGE42
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom)Svep1A2AVA02
SUZ domain-containing protein 1 (Fragment)Szrd1 D4Ertd22eA2AA852
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12) (ATP-dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1)Smarcad1 Etl1 Kiaa1122Q046922
Synaptojanin-1Synj1D3Z6562
Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1)Synj1 Kiaa0910Q8CHC42
Synaptophysin-like proteinSyplD6RFU92
Synaptosomal-associated protein 25 (SNAP-25) (Super protein) (SUP) (Synaptosomal-associated 25 kDa protein)Snap25 SnapP608792
Synaptotagmin-11 (Synaptotagmin XI) (SytXI)Syt11Q9R0N32
Synaptotagmin-5 (Synaptotagmin IX) (Synaptotagmin V) (SytV)Syt5 Syt9Q9R0N52
Synaptotagmin-like protein 2 (Exophilin-4)Sytl2 Slp2Q99N502
Syndecan-2 (SYND2) (Fibroglycan) (Heparan sulfate proteoglycan core protein) (HSPG) (CD antigen CD362)Sdc2 Hspg1 Synd2P434072
SyntaphilinSnph Kiaa0374Q80U232
Syntaxin-11Stx11Q9D3G52
Syntaxin-binding protein 5 (Lethal(2) giant larvae protein homolog 3) (Tomosyn-1)Stxbp5 Kiaa4253 Llgl3Q8K4002
Syntenin-1 (Fragment)SdcbpH3BLG52
T-cell-specific surface glycoprotein CD28 (CD antigen CD28)Cd28P310412
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65-alpha) (PAF65-alpha)Taf6l Paf65aQ8R2K42
Target of rapamycin complex 2 subunit MAPKAP1 (TORC2 subunit MAPKAP1) (Mitogen-activated protein kinase 2-associated protein 1) (Stress-activated map kinase-interacting protein 1) (SAPK-interacting protein 1)Mapkap1 Mip1 Sin1Q8BKH72
Targeting protein for Xklp2Tpx2A2APB82
TBC1 domain family member 10B (Protein wz3-85)Tbc1d10bQ8BHL32
TBC1 domain family member 17Tbc1d17Q8BYH72
TBC1 domain family member 9BTbc1d9b Kiaa0676Q5SVR02
Tenascin-R (TN-R) (Janusin) (Neural recognition molecule J1-160/180) (Restrictin)TnrQ8BYI92
Teneurin-3 (Ten-3) (Protein Odd Oz/ten-m homolog 3) (Tenascin-M3) (Ten-m3) (Teneurin transmembrane protein 3)Tenm3 Kiaa1455 Odz3 Tnm3Q9WTS62
Teneurin-4 (Ten-4) (Downstream of CHOP4) (Protein Odd Oz/ten-m homolog 4) (Tenascin-M4) (Ten-m4) (Teneurin transmembrane protein 4)Tenm4 Doc4 Kiaa1302 Odz4 Tnm4Q3UHK62
TetraspaninCd37Q3U4292
TetraspaninCd63Q8BT062
TetraspaninCd81Q3UWG52
Tetraspanin (Fragment)Tspan9D3YXN72
Tetraspanin-5 (Tspan-5) (Tetraspan NET-4) (Transmembrane 4 superfamily member 9)Tspan5 Tm4sf9P620802
Tetratricopeptide repeat domain 13Ttc13D3YVV02
Tetratricopeptide repeat domain 7Ttc7D3Z0R82
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 1) (TGF-beta-activated kinase 1-binding protein 1) (TAK1-binding protein 1)Tab1 Map3k7ip1Q8CF892
Thimet oligopeptidase (Thimet oligopeptidase 1)Thop1 mCG_12096A0A0R4IZY02
Thioredoxin domain-containing protein 5Txndc5A0A0R4J1Y72
Thioredoxin-related transmembrane protein 2Tmx2D3Z2J62
Thrombomodulin (TM) (Fetomodulin) (CD antigen CD141)ThbdP153062
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