EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
COP9 signalosome complex subunit 7b (SGN7b) (Signalosome subunit 7b) (JAB1-containing signalosome subunit 7b)Cops7b Csn7bQ8BV133
Copine-4 (Copine IV)Cpne4Q8BLR23
Copine-5 (Copine V)Cpne5Q8JZW43
Copine-8 (Copine VIII)Cpne8Q9DC533
Copper-transporting ATPase 1 (EC 3.6.3.54) (Copper pump 1) (Menkes disease-associated protein homolog)Atp7a MnkQ644303
Coproporphyrinogen-III oxidase, mitochondrial (COX) (Coprogen oxidase) (Coproporphyrinogenase) (EC 1.3.3.3)Cpox CpoP365523
CorneodesmosinCdsnQ7TPC13
Coronin-1C (Coronin-3)Coro1cQ9WUM43
COUP transcription factor 1 (COUP-TF1) (COUP transcription factor I) (COUP-TF I) (Nuclear receptor subfamily 2 group F member 1) (V-erbA-related protein 3) (EAR-3)Nr2f1 Erbal3 Tfcoup1Q606323
COUP transcription factor 2 (COUP-TF2) (Apolipoprotein AI regulatory protein 1) (ARP-1) (COUP transcription factor II) (COUP-TF II) (Nuclear receptor subfamily 2 group F member 2)Nr2f2 Aporp1 Arp-1 Arp1 Tfcoup2P431353
CREB-regulated transcription coactivator 3 (Transducer of regulated cAMP response element-binding protein 3) (TORC-3) (Transducer of CREB protein 3)Crtc3 Torc3Q91X843
CRKD-binding protein (Protein B430306N03Rik) (Triggering receptor expressed on myeloid cells-like 6)B430306N03Rik Crkr Treml6Q6QX363
CUE domain-containing protein 2Cuedc2Q9CXX93
Cyclin-D-binding Myb-like transcription factor 1 (Cyclin-D-interacting Myb-like protein 1) (mDmp1)Dmtf1 Dmp1Q8CE223
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)Cdk1 Cdc2 Cdc2a Cdkn1P114403
Cyclin-dependent kinase 2-associated protein 2 (CDK2-associated protein 2) (DOC-1-related protein) (DOC-1R)Cdk2ap2 D19Ertd144e Doc1rQ9CPY43
Cyclin-dependent kinase 4 (EC 2.7.11.22) (CRK3) (Cell division protein kinase 4) (PSK-J3)Cdk4 Crk3P302853
Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57Kip2)Cdkn1c Kip2P499193
Cyclin-dependent kinases regulatory subunit 1 (CKS-1) (Sid 1334)Cks1b Cks1 Sid1334P610253
Cyclin-FCcnfP519443
Cyclin-KCcnkQ3U3M53
Cyclin-T1 (CycT1) (Cyclin-T)Ccnt1Q9QWV93
Cystathionine beta-synthase (EC 4.2.1.22) (Beta-thionase) (Serine sulfhydrase)CbsQ91WT93
Cystatin-C (Cystatin-3)Cst3P214603
Cysteine-rich hydrophobic domain 1 protein (Brain X-linked protein)Chic1 BrxQ8CBW73
Cysteine-rich with EGF-like domain protein 1Creld1Q91XD73
Cysteine-rich with EGF-like domain protein 2Creld2Q9CYA03
Cysteinyl leukotriene receptor 2 (CysLTR2)Cysltr2 Cyslt2Q920A13
CystinosinCtnsP577573
Cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminic acid hydroxylase) (EC 1.14.18.2) (CMP-N-acetylneuraminate monooxygenase) (CMP-Neu5Ac hydroxylase) (CMP-NeuAc hydroxylase)CmahQ614193
Cytochrome b5Cyb5a Cyb5P563953
Cytochrome b5 reductase 4 (EC 1.6.2.2) (Flavohemoprotein b5/b5R) (b5+b5R) (N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein) (cb5/cb5R)Cyb5r4 Ncb5orQ3TDX83
Cytochrome c oxidase assembly protein 3 homolog, mitochondrial (Coiled-coil domain-containing protein 56)Coa3 Ccdc56Q9D2R63
Cytochrome c oxidase assembly protein COX14Cox14Q8BH513
Cytochrome c oxidase assembly protein COX19Cox19Q8K0C83
Cytochrome c oxidase protein 20 homologCox20 Fam36aQ9D7J43
Cytochrome c oxidase subunit 6C (Cytochrome c oxidase polypeptide VIc)Cox6cQ9CPQ13
Cytochrome c1, heme protein, mitochondrial (Complex III subunit 4) (Complex III subunit IV) (Cytochrome b-c1 complex subunit 4) (Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit) (Cytochrome c-1)Cyc1Q9D0M33
Cytochrome P450 2D9 (EC 1.14.14.1) (CYPIID9) (Cytochrome P450-16-alpha) (Cytochrome P450CA) (Testosterone 16-alpha hydroxylase)Cyp2d9 Cyp2d-9P117143
Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1)Cyp4b1Q644623
Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)Cyp4x1Q6A1523
Cytochrome P450 CYP4F16 (Cytochrome P450, family 4, subfamily f, polypeptide 16) (MCG14244, isoform CRA_a) (Protein Cyp4f16)Cyp4f16 mCG_14244Q99N173
Cytokine receptor-like factor 2 (Cytokine receptor-like molecule 2) (CRLM-2) (Thymic stromal lymphopoietin protein receptor) (TSLP receptor) (Type I cytokine receptor delta 1)Crlf2 Crlm2 Tpte2 TslprQ8CII93
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)Nck2 Grb4O550333
Cytosolic 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) (FDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L1)Aldh1l1 FthfdQ8R0Y63
Cytosolic 5'-nucleotidase 3A (EC 3.1.3.5) (Cytosolic 5'-nucleotidase 3) (Cytosolic 5'-nucleotidase III) (cN-III) (Lupin) (Pyrimidine 5'-nucleotidase 1) (P5'N-1) (P5N-1) (PN-I)Nt5c3a Nt5c3Q9D0203
DAZ-associated protein 2 (Deleted in azoospermia-associated protein 2) (Proline-rich protein expressed in brain)Dazap2 PrtbQ9DCP93
DCN1-like protein 5 (DCUN1 domain-containing protein 5) (Defective in cullin neddylation protein 1-like protein 5)Dcun1d5Q9CXV93
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)Dcaf7 Han11 Wdr68P619633
Dead end protein homolog 1 (RNA-binding motif, single-stranded-interacting protein 4)Dnd1 Rbms4 TerQ6VY053
Decidual PRL-related protein (Decidual/trophoblast prolactin-related protein, isoform CRA_a) (Protein Prl8a2)Prl8a2 dPRP Dtprp mCG_4896O548323
Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-)Dhrs1 D14ertd484eQ99L043
Delta(24)-sterol reductase (EC 1.3.1.72) (24-dehydrocholesterol reductase) (3-beta-hydroxysterol delta-24-reductase)Dhcr24 Kiaa0018Q8VCH63
Delta-aminolevulinic acid dehydratase (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase)Alad LvP105183
DENN domain-containing protein 1C (Connecdenn 3)Dennd1cQ8CFK63
Deoxynucleotidyltransferase terminal-interacting protein 1 (Terminal deoxynucleotidyltransferase-interacting factor 1) (TdIF1) (TdT-interacting factor 1)Dnttip1 Tdif1Q99LB03
Dephospho-CoA kinase domain-containing proteinDcakdQ8BHC43
Desmocollin-3Dsc3P558503
Destrin (Actin-depolymerizing factor) (ADF) (Sid 23)Dstn Dsn Sid23Q9R0P53
DET1- and DDB1-associated protein 1Dda1Q9D9Z53
Deubiquitinating protein VCIP135 (EC 3.4.19.12) (Valosin-containing protein p97/p47 complex-interacting protein 1) (Valosin-containing protein p97/p47 complex-interacting protein p135)Vcpip1 Vcip135Q8CDG33
Developmental pluripotency-associated protein 2 (Embryonic stem cell-associated transcript 15-2 protein) (ECAT15-2) (Pluripotent embryonic stem cell-related gene 1 protein)Dppa2 Phsecrg1Q9CWH03
Developmental pluripotency-associated protein 5A (mDppa5) (ES cell-associated transcript 2 protein) (Embryonal stem cell-specific gene 1 protein) (ESG-1) (Protein pH 34)Dppa5a Dppa5 Ecat2 Esg1 Ph34Q9CQS73
Diacylglycerol O-acyltransferase 2 (EC 2.3.1.20) (Acyl-CoA retinol O-fatty-acyltransferase) (ARAT) (Retinol O-fatty-acyltransferase) (EC 2.3.1.76) (Diglyceride acyltransferase 2)Dgat2Q9DCV33
Dihydrofolate reductase (EC 1.5.1.3)DhfrP003753
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2)DlatQ8BMF43
Dihydropteridine reductase (EC 1.5.1.34) (HDHPR) (Quinoid dihydropteridine reductase)Qdpr DhprQ8BVI43
Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC 1.14.13.8) (Dimethylaniline oxidase 1) (Hepatic flavin-containing monooxygenase 1) (FMO 1)Fmo1 Fmo-1P502853
Dipeptidyl peptidase 3 (EC 3.4.14.4) (Dipeptidyl aminopeptidase III) (Dipeptidyl arylamidase III) (Dipeptidyl peptidase III) (DPP III) (Enkephalinase B)Dpp3Q99KK73
Dipeptidyl peptidase 8 (DP8) (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DPP VIII)Dpp8Q80YA73
Diphosphomevalonate decarboxylase (EC 4.1.1.33) (Mevalonate (diphospho)decarboxylase) (MDDase) (Mevalonate pyrophosphate decarboxylase)MvdQ99JF53
Diphthamide biosynthesis protein 2 (DPH2 homolog) (Diphthamide biosynthesis protein 2 homolog-like 2) (DPH2-like 2) (MmDph2)Dph2 Dph2l2Q9CR253
DIS3-like exonuclease 2 (EC 3.1.13.-)Dis3l2Q8CI753
Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein)Dab2 Doc2P980783
Disco-interacting protein 2 homolog B (DIP2 homolog B)Dip2b Kiaa1463Q3UH603
Disintegrin and metalloproteinase domain-containing protein 15 (ADAM 15) (EC 3.4.24.-) (AD56) (Metalloprotease RGD disintegrin protein) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15) (MDC-15) (Metargidin)Adam15 Mdc15O888393
Disintegrin and metalloproteinase domain-containing protein 23 (ADAM 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3)Adam23 Mdc3Q9R1V73
DmX-like protein 1 (X-like 1 protein)Dmxl1Q6PNC03
DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (EC 2.1.1.37) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA)Dnmt3aO885083
DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2)Ddb2Q99J793
DNA methyltransferase 1-associated protein 1 (DNMAP1) (DNMT1-associated protein 1) (MAT1-mediated transcriptional repressor)Dmap1 MmtrQ9JI443
DNA mismatch repair protein Msh6 (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS-alpha 160 kDa subunit) (p160)Msh6 GtmbpP542763
DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A)Pole Pole1Q9WVF73
DNA polymerase epsilon subunit 4 (EC 2.7.7.7) (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12)Pole4Q9CQ363
DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein homolog)Polh Rad30a XpvQ9JJN03
DNA polymerase sigma (EC 2.7.7.7) (PAP-associated domain-containing protein 7)Papd7 PolsQ6PB753
DNA primase large subunit (EC 2.7.7.-) (DNA primase 58 kDa subunit) (p58)Prim2P336103
DNA repair protein-complementing XP-G cells homologErcc5E9QM613
DNA replication licensing factor MCM5 (Minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)) (Minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae), isoform CRA_a)Mcm5 mCG_14998Q52KC33
DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme)Top2a Top-2 Top2Q013203
DNA-3-methyladenine glycosylase (EC 3.2.2.21) (3-alkyladenine DNA glycosylase) (3-methyladenine DNA glycosidase) (ADPG) (N-methylpurine-DNA glycosylase)Mpg Mid1Q048413
DNA-binding protein Ikaros (Zinc finger protein, subfamily 1A, 1 (Ikaros), isoform CRA_a)Ikzf1 Zfpn1a1 mCG_3994G5E8H33
DNA-binding protein inhibitor ID-2 (Inhibitor of DNA binding 2)Id2 Id-2 Idb2P411363
DNA-binding protein RFXANK (Ankyrin repeat-containing adapter protein Tvl-1) (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein)Rfxank Rfxb Tvl1Q9Z2053
DNA-directed RNA polymerase I subunit RPA49 (RNA polymerase I subunit A49) (DNA-directed RNA polymerase I subunit E) (RNA polymerase I-associated factor 1) (RNA polymerase I-associated factor 53)Polr1e Paf53 Praf1Q8K2023
DNA-directed RNA polymerase III subunit RPC6 (RNA polymerase III subunit C6) (DNA-directed RNA polymerase III subunit F)Polr3fQ921X63
DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RNA polymerases I, II, and III subunit ABC1) (DNA-directed RNA polymerase II subunit E) (RPB5 homolog)Polr2eQ80UW83
DNA/RNA-binding protein KIN17 (Binding to curved DNA) (KIN, antigenic determinant of recA protein)Kin Btcd Kin17Q8K3393
DnaJ homolog subfamily A member 4 (MmDjA4)Dnaja4Q9JMC33
DnaJ homolog subfamily B member 12 (mDj10)Dnajb12Q9QYI43
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