EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
UAP56-interacting factor (Forty-two-three domain-containing protein 1) (Protein 40-2-3)Fyttd1 UifQ91Z494
Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1)Ubqln1 Plic1Q8R3174
Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.4.19.12) (Deubiquitinating enzyme 19) (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19)Usp19 Kiaa0891Q3UJD64
Ubiquitin-60S ribosomal protein L40 (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; 60S ribosomal protein L40 (CEP52)]Uba52 Ubcep2P629844
Ubiquitin-conjugating enzyme E2 variant 2 (Ubc-like protein MMS2)Ube2v2 Mms2 Uev2Q9D2M84
Ubiquitin-like protein FUBI (Monoclonal non-specific suppressor factor beta) (MNSF-beta)FauP355454
Ubl carboxyl-terminal hydrolase 18 (EC 3.4.19.-) (43 kDa ISG15-specific protease) (ISG15-specific-processing protease) (Ubl thioesterase 18)Usp18 Ubp43Q9WTV64
UDP-xylose and UDP-N-acetylglucosamine transporter (Solute carrier family 35 member B4)Slc35b4 MNCb-4414Q8CIA54
Uncharacterized protein C15orf41 homolog0Q3U4G04
Uncharacterized protein C17orf80 homologD11Wsu47eQ6PIX94
Uncharacterized protein C3orf18 homolog0Q8BGK94
Uncharacterized protein C3orf38 homolog0Q3TTL04
Uncharacterized protein C4orf32 homolog0Q9CZL24
Uncharacterized protein C9orf40 homolog0Q8VCE44
UPF0469 protein KIAA0907Kiaa0907Q3TCX34
UPF0501 protein KIAA1430Kiaa1430Q6ZPR14
UPF0505 protein C16orf62 homolog0Q8BWQ64
UV excision repair protein RAD23 homolog B (HR23B) (mHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58)Rad23b Mhr23bP547284
V-type proton ATPase 16 kDa proteolipid subunit (V-ATPase 16 kDa proteolipid subunit) (PL16) (Vacuolar proton pump 16 kDa proteolipid subunit)Atp6v0c Atp6c Atp6l Atpl MvpP630824
V-type proton ATPase subunit F (V-ATPase subunit F) (V-ATPase 14 kDa subunit) (Vacuolar proton pump subunit F)Atp6v1f Atp6s14 VatfQ9D1K24
V-type proton ATPase subunit G 1 (V-ATPase subunit G 1) (V-ATPase 13 kDa subunit 1) (Vacuolar proton pump subunit G 1)Atp6v1g1 Atp6g1Q9CR514
Vacuolar protein sorting-associated protein 18 homologVps18Q8R3074
Vacuolar protein-sorting-associated protein 36 (ESCRT-II complex subunit VPS36)Vps36Q91XD64
Vascular cell adhesion protein 1 (V-CAM 1) (VCAM-1) (CD antigen CD106)Vcam1 Vcam-1P295334
Vascular endothelial growth factor C (VEGF-C) (Flt4 ligand) (Flt4-L) (Vascular endothelial growth factor-related protein) (VRP)VegfcP979534
Vasculin-like protein 1 (GC-rich promoter-binding protein 1-like 1)Gpbp1l1Q6NZP24
Vasopressin V1a receptor (V1aR) (AVPR V1a) (Antidiuretic hormone receptor 1a) (Vascular/hepatic-type arginine vasopressin receptor)Avpr1aQ624634
WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21) (WW domain-containing-binding protein 4)Wbp4 Fbp21 Fnbp21Q610484
Zinc finger protein 18 (Zinc finger protein 535) (Zinc finger protein with KRAB and SCAN domains 6)Znf18 Zfp535 Zkscan6Q810A14
Zinc finger protein 706Znf706 Zfp706Q9D1154
Zinc finger protein 830 (Coiled-coil domain-containing protein 16) (Ovus mutant candidate gene 1 protein)Znf830 Ccdc16 Omcg1 Zfp830Q8R1N04
Zinc finger protein basonuclin-2Bnc2Q8BMQ34
Zinc finger protein Helios (Ikaros family zinc finger protein 2)Ikzf2 Helios Zfpn1a2 Znfn1a2P811834
Zinc finger protein with KRAB and SCAN domains 1Zkscan1Q8BGS34
Zinc finger protein ZPR1 (Zinc finger protein 259)Znf259 Zfp259 Zpr1Q623844
Zinc finger X-chromosomal proteinZfxP170124
Zinc transporter 4 (ZnT-4) (Lethal milk protein) (Solute carrier family 30 member 4)Slc30a4 Lm Znt4O351494
Zinc transporter 6 (ZnT-6) (Solute carrier family 30 member 6)Slc30a6 Znt6Q8BJM54
ZW10 interactor (ZW10-interacting protein 1) (Zwint-1)Zwint D10Ertd749eQ9CQU54
[Protein ADP-ribosylarginine] hydrolase-like protein 1 (EC 3.2.-.-) (ADP-ribosylhydrolase 2)Adprhl1 Arh2Q8BGK24
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) (Acireductone dioxygenase (Fe(2+)-requiring)) (ARD) (Fe-ARD) (Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1) (MTCBP-1)Adi1 Mtcbp1Q99JT93
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 4) (1-AGP acyltransferase 4) (1-AGPAT 4) (Lysophosphatidic acid acyltransferase delta) (LPAAT-delta)Agpat4Q8K4X73
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)Plcb1 PlcbQ9Z1B33
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-2) (Phospholipase C-beta-2) (PLC-beta-2)Plcb2A3KGF73
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-gamma-2) (PLC-gamma-2)Plcg2Q8CIH53
14-3-3 protein gamma [Cleaved into: 14-3-3 protein gamma, N-terminally processed]YwhagP619823
24-hydroxycholesterol 7-alpha-hydroxylase (EC 1.14.13.99) (Cytochrome P450 39A1) (mCYP39A1) (Oxysterol 7-alpha-hydroxylase)Cyp39a1Q9JKJ93
26S protease regulatory subunit 10B (26S proteasome AAA-ATPase subunit RPT4) (Proteasome 26S subunit ATPase 6) (Proteasome subunit p42)Psmc6 Sug2P623343
28S ribosomal protein S36, mitochondrial (MRP-S36) (S36mt)Mrps36Q9CQX83
3-hydroxybutyrate dehydrogenase type 2 (EC 1.1.1.-) (EC 1.1.1.30) (Dehydrogenase/reductase SDR family member 6) (R-beta-hydroxybutyrate dehydrogenase)Bdh2 Dhrs6Q8JZV93
3-ketoacyl-CoA thiolase A, peroxisomal (EC 2.3.1.16) (Acetyl-CoA acyltransferase A) (Beta-ketothiolase A) (Peroxisomal 3-oxoacyl-CoA thiolase A)Acaa1a Acaa1Q921H83
3-ketodihydrosphingosine reductase (KDS reductase) (EC 1.1.1.102) (3-dehydrosphinganine reductase) (Follicular variant translocation protein 1 homolog) (FVT-1)Kdsr Fvt1Q6GV123
39S ribosomal protein L2, mitochondrial (L2mt) (MRP-L2)Mrpl2Q9D7733
39S ribosomal protein L20, mitochondrial (L20mt) (MRP-L20)Mrpl20Q9CQL43
39S ribosomal protein L30, mitochondrial (L30mt) (MRP-L30)Mrpl30Q9D7N63
39S ribosomal protein L32, mitochondrial (L32mt) (MRP-L32) (Heart-expressed gene 1 protein)Mrpl32 Heg1Q9DCI93
39S ribosomal protein L37, mitochondrial (L37mt) (MRP-L37)Mrpl37Q921S73
39S ribosomal protein L42, mitochondrial (L42mt) (MRP-L42) (28S ribosomal protein S32, mitochondrial) (MRP-S32) (S32mt) (39S ribosomal protein L31, mitochondrial) (L31mt) (MRP-L31)Mrpl42 D10Ertd322e Mrps32Q9CPV33
39S ribosomal protein L9, mitochondrial (L9mt) (MRP-L9)Mrpl9Q99N943
40S ribosomal protein S3Rps3P629083
5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)Prkaa2Q8BRK83
5'-AMP-activated protein kinase subunit gamma-1 (AMPK gamma1) (AMPK subunit gamma-1) (AMPKg)Prkag1 PrkaacO549503
5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1)Azi1 Az1 AziQ620363
5-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) (Serotonin receptor 3A) (Serotonin-gated ion channel receptor)Htr3a 5ht3 Htr3P239793
5-hydroxytryptamine receptor 7 (5-HT-7) (5-HT7) (5-HT-X) (Serotonin receptor 7)Htr7P323043
6-phosphofructokinase type C (EC 2.7.1.11) (Phosphofructo-1-kinase isozyme C) (PFK-C) (Phosphofructokinase 1) (Phosphohexokinase)Pfkp PfkcQ9WUA33
60S acidic ribosomal protein P2Rplp2P990273
60S ribosomal protein L17 (MCG123291, isoform CRA_d) (MCG50776) (Ribosomal protein L17)Rpl17 mCG_123291 mCG_50776Q6ZWZ73
60S ribosomal protein L18aRpl18aP627173
60S ribosomal protein L22-like 1Rpl22l1Q9D7S73
60S ribosomal protein L28Rpl28P411053
60S ribosomal protein L36Rpl36 mCG_20352Q6ZWZ43
A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAM-TS 2) (ADAM-TS2) (ADAMTS-2) (EC 3.4.24.14) (Procollagen I N-proteinase) (PC I-NP) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen N-endopeptidase) (pNPI)Adamts2Q8C9W33
A-kinase-interacting protein 1 (Breast cancer-associated gene 3 protein) (PKA-interacting protein) (Proline-rich protein BCA3)Akip1 Bca3Q9JJR53
Abhydrolase domain-containing protein 1 (EC 3.1.1.-) (Lung alpha/beta hydrolase 1) (MmLABH1)Abhd1 Labh1Q9QZC83
Abl interactor 1 (Abelson interactor 1) (Abi-1) (Ablphilin-1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Spectrin SH3 domain-binding protein 1) (e3B1)Abi1 Ssh3bp1Q8CBW33
Acetolactate synthase-like protein (EC 2.2.1.-) (IlvB-like protein)IlvblQ8BU333
Acetylcholinesterase collagenic tail peptide (AChE Q subunit) (Acetylcholinesterase-associated collagen)ColqO353483
Actin, cytoplasmic 2 (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]Actg1 ActgP632603
Actin-related protein 2/3 complex subunit 3 (Arp2/3 complex 21 kDa subunit) (p21-ARC)Arpc3Q9JM763
Actin-related protein 2/3 complex subunit 4 (Arp2/3 complex 20 kDa subunit) (p20-ARC)Arpc4 Arc20P599993
Activated RNA polymerase II transcriptional coactivator p15 (Positive cofactor 4) (PC4) (SUB1 homolog) (Single-stranded DNA-binding protein p9) (p14)Sub1 Pc4 Rpo2tc1P110313
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (EC 2.3.1.-)Lpgat1 Fam34aQ91YX53
Acyl-coenzyme A synthetase ACSM1, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 1) (Butyrate--CoA ligase 1) (Butyryl-coenzyme A synthetase 1) (Lipoate-activating enzyme) (Middle-chain acyl-CoA synthetase 1)Acsm1 Bucs1 Lae Macs1Q91VA03
ADAM DEC1 (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin-1) (ADAM-like protein decysin-1)Adamdec1Q9R0X23
Adaptin ear-binding coat-associated protein 1 (NECAP endocytosis-associated protein 1) (NECAP-1)Necap1Q9CR953
Adaptin ear-binding coat-associated protein 2 (NECAP endocytosis-associated protein 2) (NECAP-2)Necap2Q9D1J13
Adenosine 3'-phospho 5'-phosphosulfate transporter 2 (PAPS transporter 2) (Solute carrier family 35 member B3)Slc35b3Q922Q53
Adenosine receptor A1Adora1Q606123
Adenylate cyclase type 10 (EC 4.6.1.1) (Germ cell soluble adenylyl cyclase) (sAC) (Testicular soluble adenylyl cyclase)Adcy10 Sac SacyQ8C0T93
Adiponectin receptor protein 1Adipor1Q91VH13
Adrenodoxin, mitochondrial (Adrenal ferredoxin) (Ferredoxin-1)Fdx1P466563
Akirin-2Akirin2B1AXD83
Alcohol dehydrogenase class-3 (EC 1.1.1.1) (Alcohol dehydrogenase 2) (Alcohol dehydrogenase 5) (Alcohol dehydrogenase B2) (ADH-B2) (Alcohol dehydrogenase class-III) (Glutathione-dependent formaldehyde dehydrogenase) (FALDH) (FDH) (GSH-FDH) (EC 1.1.1.-) (S-(hydroxymethyl)glutathione dehydrogenase) (EC 1.1.1.284)Adh5 Adh-2 Adh2P284743
Aldehyde dehydrogenase family 16 member A1Aldh16a1Q571I93
Aldehyde dehydrogenase family 3 member B1 (EC 1.2.1.5) (Aldehyde dehydrogenase 7)Aldh3b1 Aldh7Q80VQ03
Aldo-keto reductase family 1, member C19 (Protein Akr1c19)Akr1c19 mCG_114463G3X9Y63
Alkaline ceramidase 2 (AlkCDase 2) (Alkaline CDase 2) (maCER2) (EC 3.5.1.23) (Acylsphingosine deacylase 3-like) (Cancer-related gene liver 1 protein) (CRG-L1) (N-acylsphingosine amidohydrolase 3-like)Acer2 Asah3lQ8VD533
Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Alkylglycerone-phosphate synthase)AgpsQ8C0I13
Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1)Aif1 Iba1O702003
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