EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
N-alpha-acetyltransferase 11 (EC 2.3.1.255) (N-terminal acetyltransferase complex ARD1 subunit homolog B) (NatA catalytic subunit Naa11)Naa11 Ard1b Ard2Q3UX612
N-myc-interactor (Nmi) (N-myc and STAT interactor)NmiO353092
NAD-dependent protein deacetylase sirtuin-1 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (SIR2alpha) (Sir2) (mSIR2a) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)]Sirt1 Sir2l1Q923E42
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (Complex I-B14.7) (CI-B14.7) (NADH-ubiquinone oxidoreductase subunit B14.7)Ndufa11Q9D8B42
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (Complex I-B14.5a) (CI-B14.5a) (NADH-ubiquinone oxidoreductase subunit B14.5a)Ndufa7Q9Z1P62
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (Complex I-B18) (CI-B18) (NADH-ubiquinone oxidoreductase B18 subunit)Ndufb7Q9CR612
NADH dehydrogenase [ubiquinone] 1 subunit C2 (Complex I-B14.5b) (CI-B14.5b) (NADH-ubiquinone oxidoreductase subunit B14.5b)Ndufc2Q9CQ542
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrialNdufv1D3YUM12
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrialNdufs4E9QPX32
NADH-ubiquinone oxidoreductase chain 3 (EC 1.6.5.3) (NADH dehydrogenase subunit 3)Mtnd3 mt-Nd3 Nd3P038992
Nardilysin, N-arginine dibasic convertase, NRD convertase 1Nrd1A2A9Q22
NEDD8-activating enzyme E1 regulatory subunitNae1E0CZE02
Negative elongation factor D (NELF-D) (TH1-like protein)Nelfcd Nelfd Th1 Th1lQ922L62
NeogeninNeo1Q7TQG52
Nesprin-2Syne2E9QP462
Netrin-1Ntn1O091182
Netrin-3 (Netrin-2-like protein)Ntn3 Ntn2lQ9R1A32
Neudesin (Neuron-derived neurotrophic factor) (Secreted protein of unknown function) (SPUF protein)Nenf SpufQ9CQ452
Neural proliferation differentiation and control protein 1 (Fragment)Npdc1A2AJ232
Neuregulin 1 (Neuregulin-1 type I beta1-a)Nrg1Q6DR982
Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain]Notch3Q619822
Neuroguidin (EIF4E-binding protein)Ngdn NgdQ9DB962
Neuron navigator 2Nav2E9Q8422
Neuron navigator 3 (Pore membrane and/or filament-interacting-like protein 1)Nav3 Kiaa0938 Pomfil1Q80TN72
Neuron-specific calcium-binding protein hippocalcinHpcaP840752
Neutrophil cytosol factor 1Ncf1F8WH692
NF-kappa-B-activating proteinNkapQ9D0F42
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (HIRA-interacting protein 5) (mHIRIP5)Nfu1 Hirip5Q9QZ232
NHL repeat-containing protein 3Nhlrc3Q8CCH22
NicalinNclnD3YU172
Nitric oxide synthase (EC 1.14.13.39)Nos1S4R2552
Noelin (Neuronal olfactomedin-related ER localized protein) (Olfactomedin-1) (Pancortin)Olfm1 Noe1 Noel Noel1O889982
Nuclear cap-binding protein subunit 3Ncbp3Q8BZR92
Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein)NfiaQ027802
Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8)Ppp1r8 Nipp1Q8R3G12
Nuclear receptor 2C2-associated protein (TR4 orphan receptor-associated 16 kDa protein)Nr2c2ap Tra16Q3TV702
Nuclear receptor corepressor 2 (Fragment)Ncor2F6SK532
Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)Ncor2 SmrtQ9WU422
Nuclear RNA export factor 3 (Nuclear export factor 3)Nxf3 NXF3Q4ZGD92
Nucleobindin 1, isoform CRA_b (Nucleobindin-1)Nucb1 mCG_23163A0A1C7CYU32
Nucleolar protein 58Nop58A0A0A0MQ762
Nucleolar protein 7Nol7 MNCb-1192Q9D7Z32
Nucleolysin TIA-1 (Tia1 protein)Tia1Q8CII52
Nucleotide exchange factor SIL1Sil1Q9EPK62
Numb-like proteinNumbl NblO089192
NUT family member 1 (Nuclear protein in testis)Nutm1 NutQ8BHP22
O-phosphoseryl-tRNA(Sec) selenium transferase (EC 2.9.1.2) (Selenocysteine synthase) (Sec synthase) (Selenocysteinyl-tRNA(Sec) synthase) (Sep-tRNA:Sec-tRNA synthase) (SepSecS) (UGA suppressor tRNA-associated protein)Sepsecs D5Ertd135eQ6P6M72
OCIA domain-containing protein 1Ociad1 AsrijQ9CRD02
Ogdhl proteinOgdhlB2RXT32
Olfactory receptorOlfr599 mCG_1046593Q8VG012
OptineurinOptnQ8K3K82
Origin recognition complex subunit 4 (Fragment)Orc4A2AI402
Origin recognition complex subunit 5Orc5 Orc5lQ9WUV02
Osteopontin (Fragment)Spp1D3Z4N22
OTU domain-containing protein 4 (EC 3.4.19.12)Otud4 Kiaa1046B2RRE72
Out at first protein homologOaf D9Ucla1Q8QZR42
Outer dense fiber protein 2 (84 kDa outer dense fiber protein) (Cenexin) (Outer dense fiber of sperm tails protein 2)Odf2 Odf84A3KGV12
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (COX) (Coprogen oxidase) (Coproporphyrinogenase) (EC 1.3.3.3)Cpox CpoP365522
Oxysterol-binding proteinOsbpl9Q5FWX72
Oxysterol-binding protein-related protein 1 (ORP-1) (OSBP-related protein 1)Osbpl1a Orp1 Orp1a Orp1lQ91XL92
Oxysterol-binding protein-related protein 6 (ORP-6) (OSBP-related protein 6)Osbpl6Q8BXR92
P-selectin (CD62 antigen-like family member P) (Granule membrane protein 140) (GMP-140) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (Platelet activation dependent granule-external membrane protein) (PADGEM) (CD antigen CD62P)Selp GrmpQ011022
PAB-dependent poly(A)-specific ribonuclease subunit PAN2 (EC 3.1.13.4) (Inactive ubiquitin carboxyl-terminal hydrolase 52) (PAB1P-dependent poly(A)-nuclease) (PAN deadenylation complex catalytic subunit 2)Pan2 Kiaa0710 Usp52Q8BGF72
Palmitoleoyl-protein carboxylesterase NOTUM (EC 3.1.1.98)NotumQ8R1162
Palmitoyltransferase ZDHHC13 (EC 2.3.1.225) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Zinc finger DHHC domain-containing protein 13) (DHHC-13)Zdhhc13 Hip14lQ9CWU22
Palmitoyltransferase ZDHHC15 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 15) (DHHC-15)Zdhhc15Q8BGJ02
Pantothenate kinase 1 (mPank) (mPank1) (EC 2.7.1.33) (Pantothenic acid kinase 1)Pank1 PankQ8K4K62
Pantothenate kinase 2 (Pantothenate kinase 2 (Hallervorden-Spatz syndrome)) (Putative uncharacterized protein)Pank2Q3U4S02
Pappalysin 2Pappa2E9PZ872
Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A)PappaQ8R4K82
Partner of Y14 and mago (PYM homolog 1 exon junction complex-associated factor) (Protein wibg homolog)Pym1 Pym WibgQ8CHP52
Pcdhgc3 proteinPcdhgc3Q4KMN62
PCI domain-containing protein 2 (CSN12-like protein)Pcid2Q8BFV22
PDZ domain-containing protein 11Pdzd11 Pdzk11Q9CZG92
Pentatricopeptide repeat domain-containing protein 3, mitochondrial (28S ribosomal protein S39, mitochondrial) (MRP-S39)Ptcd3 Mrps39Q14C512
Peptidase inhibitor 16 (PI-16) (Cysteine-rich protease inhibitor)Pi16 CripiQ9ET662
Peptide deformylase (EC 3.5.1.88)PdfS4R2K02
Peptidoglycan recognition protein 3 (Peptidoglycan recognition protein I-alpha) (PGLYRPIalpha) (PGRP-I-alpha) (Peptidoglycan recognition protein intermediate alpha)Pglyrp3 Gm420 PgrpiaA1A5472
Peptidyl-glycine alpha-amidating monooxygenase (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (PHM) (EC 1.14.17.3); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)]PamP974672
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8)Ppia mCG_121511Q9CZK92
Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (mFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase)Fkbp8 Fkbp38 Sam11O354652
Peptidyl-prolyl cis-trans isomerase-like 3 (PPIase) (EC 5.2.1.8) (CYP10L) (Cyclophilin-like protein PPIL3) (Rotamase PPIL3)Ppil3 Cyp10lQ9D6L82
Peptidyl-tRNA hydrolase ICT1, mitochondrial (EC 3.1.1.29) (39S ribosomal protein L58, mitochondrial) (MRP-L58) (Immature colon carcinoma transcript 1 protein homolog)Mrpl58 Ict1Q8R0352
Peroxiredoxin-1 (Fragment)Prdx1B1AXW52
Peroxiredoxin-4 (Fragment)Prdx4B1AZS92
Peroxisomal acyl-coenzyme A oxidase 3 (EC 1.3.3.6) (Branched-chain acyl-CoA oxidase) (BRCACox) (Pristanoyl-CoA oxidase)Acox3Q9EPL92
Persulfide dioxygenase ETHE1, mitochondrial (EC 1.13.11.18) (Ethylmalonic encephalopathy protein 1 homolog) (Hepatoma subtracted clone one protein) (Sulfur dioxygenase ETHE1)Ethe1 HscoQ9DCM02
PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4)Psd4Q8BLR52
PHD finger protein 6Phf6 Kiaa1823Q9D4J72
Phosphatidylcholine translocator ABCB4 (ATP-binding cassette sub-family B member 4) (Multidrug resistance protein 2) (Multidrug resistance protein 3) (EC 3.6.3.44) (P-glycoprotein 2) (P-glycoprotein 3)Abcb4 Mdr2 Pgy-2 Pgy2P214402
Phosphatidylcholine-sterol acyltransferase (EC 2.3.1.43) (Lecithin-cholesterol acyltransferase) (Phospholipid-cholesterol acyltransferase)LcatP163012
Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta)Pik3r2O089082
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) (PI3K-gamma) (PI3Kgamma) (PtdIns-3-kinase subunit gamma) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma) (PtdIns-3-kinase subunit p110-gamma) (p110gamma) (Phosphoinositide-3-kinase catalytic gamma polypeptide) (Serine/threonine protein kinase PIK3CG) (EC 2.7.11.1) (p120-PI3K)Pik3cg Pi3kg1Q9JHG72
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alphaPik3c2aF8VPL22
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma (Fragment)Pik3c2gE9QQ352
Phosphoenolpyruvate carboxykinase [GTP], mitochondrialPck2A0A0R4J0G02
Phosphoglycerate mutase 2 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 2) (Muscle-specific phosphoglycerate mutase) (Phosphoglycerate mutase isozyme M) (PGAM-M)Pgam2O702502
Phosphoinositide 3-kinase adapter protein 1 (B-cell adapter for phosphoinositide 3-kinase) (B-cell phosphoinositide 3-kinase adapter protein 1)Pik3ap1 BcapQ9EQ322
Phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5) (PI3-kinase p101 subunit) (Phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit) (PtdIns-3-kinase regulatory subunit) (PtdIns-3-kinase p101) (p101-PI3K)Pik3r5Q5SW282
Phosphoinositide 3-kinase regulatory subunit 6 (Phosphoinositide 3-kinase gamma adapter protein of 87 kDa) (p84 PI3K adapter protein) (p84 PIKAP) (p87 PI3K adapter protein) (p87PIKAP)Pik3r6Q3U6Q42
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