EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Interleukin enhancer-binding factor 3 (Nuclear factor 90)Ilf3Q45VK52
Interleukin-1 family member 10 (IL-1F10)Il1f10Q8R4592
Interleukin-1 receptor accessory proteinIl1rapG3UY132
Interleukin-1 receptor type 2 (IL-1R-2) (IL-1RT-2) (IL-1RT2) (CD121 antigen-like family member B) (IL-1 type II receptor) (Interleukin-1 receptor beta) (IL-1R-beta) (Interleukin-1 receptor type II) (CD antigen CD121b) [Cleaved into: Interleukin-1 receptor type 2, membrane form (mIL-1R2) (mIL-1RII); Interleukin-1 receptor type 2, soluble form (sIL-1R2) (sIL-1RII)]Il1r2 Il-1r2 Il1rbP279312
Interleukin-1 receptor-associated kinase 3 (IRAK-3) (EC 2.7.11.1) (IL-1 receptor-associated kinase M) (IRAK-M)Irak3Q8K4B22
Interleukin-6 receptor subunit betaIl6stV9GX002
Interleukin-7 receptor subunit alpha (IL-7 receptor subunit alpha) (IL-7R subunit alpha) (IL-7R-alpha) (IL-7RA) (CD antigen CD127)Il7rP168722
Intersectin-2 (EH domain and SH3 domain regulator of endocytosis 2) (EH and SH3 domains protein 2) (SH3 domain-containing protein 1B)Itsn2 Ese2 Sh3d1BQ9Z0R62
Intron-binding protein aquariusAqrA2AQA72
Inward rectifier potassium channel 2 (Inward rectifier K(+) channel Kir2.1) (IRK-1) (Potassium channel, inwardly rectifying subfamily J member 2)Kcnj2 Irk1P355612
IQ domain-containing protein GIqcgQ80W322
IQ motif and SEC7 domain-containing protein 1Iqsec1 Kiaa0763Q8R0S22
IQ motif-containing GTPase-activating protein 3 (Putative uncharacterized protein)Iqgap3Q3UQP12
Islet cell autoantigen 1 (Fragment)Ica1D3Z3762
Isochorismatase domain-containing protein 1Isoc1Q91V642
Josephin-1 (EC 3.4.19.12) (Josephin domain-containing protein 1)Josd1Q9DBJ62
JouberinAhi1E9QP542
Kallikrein 6, isoform CRA_a (Kallikrein-related-peptidase 6) (Klk6 protein) (Neurosin) (Putative uncharacterized protein)Klk6 Prss18 mCG_133315Q91Y822
Kelch domain-containing protein 4Klhdc4Q921I22
Kelch-like protein 20 (Kelch-like ECT2-interacting protein)Klhl20 Kiaa4210 KleipQ8VCK52
Kelch-like protein 22Klhl22 KelchlQ99JN22
Keratin 83Krt83 5430421N21RikE9Q1Y92
Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2) (Keratin-32) (K32)Krt32 Hka2 Krt1-2 Krtha2Q621682
Keratin, type I cuticular Ha3-II (Hair keratin, type I Ha3) (Keratin, type I cuticular Ha3) (Keratin-33B) (K33B)Krt33b Hka3 Krt1-3Q618972
Keratin, type I cuticular Ha6 (Keratin-36) (K36) (Keratin-5) (MHRa-1) (Type I keratin 48 kDa)Krt36 Hra-1 Krt1-22 Krt1-5B1AQ752
Keratin, type I cytoskeletal 27 (Cytokeratin-27) (CK-27) (Keratin complex-1, acidic, gene C29) (Keratin-27) (K27) (Type I inner root sheath-specific keratin-K25irs3)Krt27 c29 Krt1-c29Q9Z3202
Keratin, type I cytoskeletal 28 (Cytokeratin-28) (CK-28) (Keratin-25D) (K25D) (Keratin-28) (K28) (Type I inner root sheath-specific keratin-K25irs4)Krt28 Krt25dA6BLY72
Keratin, type I cytoskeletal 40 (Cytokeratin-40) (CK-40) (Keratin-40) (K40) (Type I hair keratin Ka36)Krt40 Ka36Q6IFX32
Keratin, type II cuticular Hb1 (Keratin-81) (K81) (Type II hair keratin Hb1)Krt81 Krt2-19Q9ERE22
Keratin, type II cuticular Hb2 (Keratin-82) (K82) (Type II hair keratin Hb2) (Type-II keratin Kb22)Krt82 Krt2-20 Krthb2Q99M742
Keratin, type II cuticular Hb6 (Keratin-86) (K86) (Type II hair keratin Hb6) (Type-II keratin Kb26)Krt86 Krt2-10 Krthb6P978612
Keratin, type II cytoskeletal 74 (Keratin-74) (K74) (Type-II keratin Kb37)Krt74 Kb37Q6IFZ92
Kinesin light chain 1Klc1E9Q7C92
Kinesin-like protein KIF18BKif18bQ6PFD62
Kinesin-like protein KIF21AKif21aF8WGN62
Kinesin-like protein KIF21B (Kinesin-like protein KIF6)Kif21b Kif6Q9QXL12
Kinetochore protein Nuf2 (Cell division cycle-associated protein 1)Nuf2 Cdca1 Nuf2rQ99P692
Kinetochore protein Spc24Spc24 Spbc24Q9D0832
KxDL motif-containing protein 1 (Fragment)Kxd1 2810422J05RikE9Q4P02
L-lactate dehydrogenase (EC 1.1.1.27) (Fragment)LdhbD3Z7F02
L-selectin (CD62 antigen-like family member L) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (Lymph node homing receptor) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (CD antigen CD62L)Sell Lnhr Ly-22 Ly22P183372
La-related protein 4Larp4E9Q0662
Lamin tail domain-containing protein 2Lmntd2Q0VET52
Laminin subunit gamma-3 (Laminin-12 subunit gamma) (Laminin-14 subunit gamma) (Laminin-15 subunit gamma)Lamc3Q9R0B62
Large neutral amino acids transporter small subunit 3 (L-type amino acid transporter 3) (Solute carrier family 43 member 1)Slc43a1 Lat3Q8BSM72
Late secretory pathway protein AVL9 homologAvl9 Kiaa0241Q80U562
Latent-transforming growth factor beta-binding protein 2Ltbp2E9QNQ32
Latent-transforming growth factor beta-binding protein 3 (LTBP-3)Ltbp3Q618102
Leiomodin-3Lmod3E9QA622
Leucine rich repeat containing 40, isoform CRA_a (Leucine-rich repeat-containing protein 40)Lrrc40 mCG_11659A0A0R4J0W62
Leucine zipper putative tumor suppressor 2 (Protein LAPSER1)Lzts2 Kiaa1813 Lapser1Q91YU62
Leucine-rich HEV glycoprotein (Leucine-rich alpha-2-glycoprotein) (Leucine-rich alpha-2-glycoprotein 1)Lrg1 Lrg lrhg mCG_22979Q91XL12
Leucine-rich repeat transmembrane protein FLRT3 (Fibronectin leucine rich transmembrane protein 3)Flrt3 Kiaa1469Q8BGT12
Leucine-rich repeat-containing G-protein coupled receptor 4 (G-protein coupled receptor 48)Lgr4 Gpr48A2ARI42
Leucine-rich repeat-containing protein 41 (Protein Muf1)Lrrc41 Muf1Q8K1C92
Leucine-rich repeat-containing protein 4B (Netrin-G3 ligand) (NGL-3)Lrrc4b Lrig4P0C1922
Leucine-rich repeat-containing protein 57 (Fragment)Lrrc57A2AKH72
Leucine-rich repeat-containing protein 58Lrrc58Q3UGP92
Leukocyte elastase inhibitor B (Serine protease inhibitor EIB) (Serpin B1b)Serpinb1bQ8VHP72
LeupaxinLpxnQ99N692
LIM and cysteine-rich domains protein 1Lmcd1Q8VEE12
LIM and senescent cell antigen-like-containing domain proteinLims1 mCG_19016Q9D7B22
LIM domain-containing protein 1Limd1Q9QXD82
Limb and neural patterns, isoform CRA_c (Lunapark, ER junction formation factor)Lnpk Lnp Lnpk1 mCG_13964A2ASL82
Limbic system-associated membrane protein (LSAMP)LsampQ8BLK32
Linker for activation of T-cells family member 1 (36 kDa phospho-tyrosine adapter protein) (pp36) (p36-38)LatO549572
Lipase maturation factor 1 (Transmembrane protein 112)Lmf1 Tmem112Q3U3R42
Lipase maturation factor 2 (Transmembrane protein 112B) (Transmembrane protein 153)Lmf2 Tmem112b Tmem153Q8C3X82
Lipoma HMGIC fusion partner-like 2 proteinLhfpl2Q8BGA22
Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog (LPS-induced TNF-alpha factor homolog) (Estrogen-enhanced transcript protein) (mEET) (LITAF-like protein) (NEDD4 WW domain-binding protein 3)Litaf N4wbp3 Tbx1Q9JLJ02
Liprin-alpha 1Ppfia1 ppfia1B8QI332
LisH domain and HEAT repeat-containing protein KIAA1468Kiaa1468Q148V72
Lon protease homolog 2, peroxisomal (EC 3.4.21.-) (Lon protease-like protein 2) (Lon protease 2) (Peroxisomal Lon protease)Lonp2Q9DBN52
Long-chain-fatty-acid--CoA ligase 3Acsl3E9PUC22
Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 5) (LACS 5)Acsl5 Facl5Q8JZR02
Long-chain-fatty-acid--CoA ligase ACSBG1 (EC 6.2.1.3) (Acyl-CoA synthetase bubblegum family member 1) (mBG1) (Gonadotropin-regulated long chain acyl CoA synthetase) (GR-LACS) (Lipidosin)Acsbg1 Kiaa0631 LpdQ99PU52
Long-chain-specific acyl-CoA dehydrogenase, mitochondrialAcadlA0A0R4J0832
Low affinity immunoglobulin gamma Fc region receptor III (IgG Fc receptor III) (Fc-gamma RIII) (FcRIII) (CD antigen CD16)Fcgr3P085082
Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7) (Lr3)Lrp5 Lrp7Q91VN02
LRRN4 C-terminal-like proteinLrrn4clQ3TYX22
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae), isoform CRA_b (Lsm4 protein) (Putative uncharacterized protein) (U6 snRNA-associated Sm-like protein LSm4)Lsm4 mCG_14793Q9CY462
Ly6/PLAUR domain-containing protein 3 (GPI-anchored metastasis-associated protein C4.4A homolog)Lypd3 C4.4aQ91YK82
Lymphocyte antigen 6A-2/6E-1 (Ly-6A.2/Ly-6E.1) (Stem cell antigen 1) (SCA-1) (T-cell-activating protein) (TAP)Ly6a Ly6P055332
Lymphocyte antigen 6C2 (Ly-6C2)Ly6c2 Ly6cP0CW032
Lymphocyte antigen 6G (Ly-6G) (Ly-6G.1) (Fragment)Ly6gP354612
Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76)Lcp2Q607872
Lymphocyte-specific protein 1 (52 kDa phosphoprotein) (pp52) (Lymphocyte-specific antigen WP34) (S37 protein)Lsp1 Pp52 S37 Wp34P199732
Lysine--tRNA ligase (EC 6.1.1.6) (Lysyl-tRNA synthetase)Kars mCG_141545Q8R2P82
Lysine-specific demethylase 2A (EC 1.14.11.27) (F-box and leucine-rich repeat protein 11) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A)Kdm2a Fbxl11 Jhdm1a Kiaa1004P599972
Lysine-specific demethylase 3A (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 2A) (Jumonji domain-containing protein 1A)Kdm3a Jhdm2a Jmjd1a Kiaa0742Q6PCM12
Lysine-specific demethylase PHF2 (EC 1.14.11.-) (GRC5) (PHD finger protein 2)Phf2 Kiaa0662Q9WTU02
Lysine-specific histone demethylase 1AKdm1aA3KG932
Lysocardiolipin acyltransferase 1 (EC 2.3.1.-) (EC 2.3.1.51) (Acyl-CoA:lysocardiolipin acyltransferase 1)Lclat1 Alcat1 Gm91 LycatQ3UN022
Lysosomal membrane glycoprotein 1, isoform CRA_a (Putative uncharacterized protein)Lamp1 mCG_3708Q9DC132
Lysosomal thioesterase PPT2 (Fragment)Ppt2E9PVM92
Lysosomal-associated transmembrane protein 5 (Lysosomal-associated multitransmembrane protein 5) (Retinoic acid-inducible E3 protein)Laptm5Q611682
Macoilin (Brain-specific adapter protein C61) (Transmembrane protein 57)Tmem57Q7TQE62
Maestro heat-like repeat family member 1Mroh1 Heatr7aE0CZ222
Magnesium transporter protein 1 (Fragment)Magt1F6TBV12
Magnesium transporter protein 1 (MagT1) (Implantation-associated protein) (IAP)Magt1 Iag2Q9CQY52
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