EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
Rab9 effector protein with kelch motifsRabepkQ8VCH55
Ral GTPase-activating protein subunit beta (p170)Ralgapb Kiaa1219Q8BQZ45
Ras association domain-containing protein 1 (Protein 123F2)Rassf1Q99MK95
Ras-related protein Rab-11BRab11bP466385
Ras-related protein Rab-14Rab14Q91V415
Ras-related protein Rab-31Rab31Q921E25
Ras-related protein Rab-34 (Ras-related homolog) (Ras-related protein Rab-39) (Ras-related protein Rah)Rab34 Rab39 Rah Rah1Q640085
Ras-related protein Rab-7bRab7bQ8VEA85
Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC (PTPNU-3) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma)PtprsB0V2N15
Regulator of G-protein signaling 16 (RGS16) (A28-RGS14P) (Retinal-specific RGS) (RGS-r) (Retinally abundant regulator of G-protein signaling)Rgs16 RgsrP974285
Regulator of G-protein signaling 2 (RGS2)Rgs2O088495
Replication factor C subunit 1 (A1-P145) (Activator 1 140 kDa subunit) (A1 140 kDa subunit) (Activator 1 large subunit) (Activator 1 subunit 1) (Differentiation-specific element-binding protein) (ISRE-binding protein) (Replication factor C 140 kDa subunit) (RF-C 140 kDa subunit) (RFC140) (Replication factor C large subunit)Rfc1 Ibf-1 Recc1P356015
Retinitis pigmentosa 9 protein homolog (Pim-1-associated protein) (PAP-1)rp9 Rp9hP977625
Retinoid-inducible serine carboxypeptidase (EC 3.4.16.-) (Serine carboxypeptidase 1)Scpep1 RiscQ920A55
Retinol dehydrogenase 11 (EC (Androgen-regulated short-chain dehydrogenase/reductase 1) (Cell line MC/9.IL4-derived protein 1) (M42C60) (Prostate short-chain dehydrogenase/reductase 1) (Retinal reductase 1) (RalR1) (Short-chain aldehyde dehydrogenase) (SCALD)Rdh11 Arsdr1 Mdt1 Psdr1Q9QYF15
Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein homolog)Rhobtb2 Dbc2Q91V935
Ribosome production factor 1 (Brix domain-containing protein 5) (Ribosome biogenesis protein RPF1)Rpf1 Bxdc5Q7TND55
Ribosome-recycling factor, mitochondrial (RRF) (Ribosome-releasing factor, mitochondrial)MrrfQ9D6S75
RING finger and CHY zinc finger domain-containing protein 1 (EC 6.3.2.-) (Androgen receptor N-terminal-interacting protein) (CH-rich-interacting match with PLAG1) (E3 ubiquitin-protein ligase Pirh2) (Zinc finger protein 363)Rchy1 Arnip Chimp Zfp363 Znf363Q9CR505
RING finger protein 10 (Sid 2705)Rnf10 Kiaa0262 Rie2 Sid2705Q3UIW55
RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1)Rexo1 Kiaa1138 Tceb3bp1Q7TT285
RNA-binding motif, single-stranded-interacting protein 2Rbms2Q8VC705
RNMT-activating mini protein (RAM) (Protein FAM103A1)Fam103a1Q9CQY25
S-adenosylmethionine decarboxylase proenzyme 1 (AdoMetDC 1) (SAMDC 1) (EC [Cleaved into: S-adenosylmethionine decarboxylase 1 alpha chain; S-adenosylmethionine decarboxylase 1 beta chain]Amd1P311545
SAFB-like transcription modulator (Modulator of estrogen-induced transcription) (SAF-like transcription modulator)Sltm MetQ8CH255
Sel1 repeat-containing protein 1 (Beta-lactamase hcp-like protein)Selrc1Q921H95
Serine-threonine kinase receptor-associated protein (UNR-interacting protein)Strap UnripQ9Z1Z25
Serine/threonine-protein kinase PDIK1L (EC (PDLIM1-interacting kinase 1-like)Pdik1lQ8QZR75
Serine/threonine-protein kinase RIO3 (EC (RIO kinase 3)Riok3Q9DBU35
Serine/threonine-protein phosphatase 6 regulatory subunit 3 (SAPS domain family member 3)Ppp6r3 D19Ertd703e Kiaa1558 Pp6r3 Saps3Q922D45
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC (EC
Short-chain dehydrogenase/reductase family 9C member 7 (EC 1.1.1.-) (Orphan short-chain dehydrogenase/reductase) (SDR-O) (RDH-S)Sdr9c7 Rdhs SdroQ8K3P05
Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Solute carrier family 17 member 5) (Vesicular H(+)/Aspartate-glutamate cotransporter)Slc17a5Q8BN825
Signal peptide peptidase-like 3 (SPP-like 3) (EC 3.4.23.-) (Intramembrane protease 2) (IMP-2) (Presenilin-like protein 4)Sppl3 Imp2 Psl4 Usmg3Q9CUS95
Single-stranded DNA-binding protein, mitochondrial (Mt-SSB) (MtSSB)Ssbp1Q9CYR05
SLAIN motif-containing protein 2Slain2 Kiaa1458Q8CI085
Smad nuclear-interacting protein 1Snip1Q8BIZ65
SNF-related serine/threonine-protein kinase (EC (SNF1-related kinase)SnrkQ8VDU55
Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6)Slc6a6 TautO353165
Sodium/hydrogen exchanger 8 (Na(+)/H(+) exchanger 8) (NHE-8) (Solute carrier family 9 member 8)Slc9a8 Nhe8Q8R4D15
Sodium/potassium-transporting ATPase subunit beta-1 (Sodium/potassium-dependent ATPase subunit beta-1)Atp1b1 Atp4bP140945
Solute carrier family 25 member 39Slc25a39 D11Ertd333eQ9D8K85
Sorting nexin-10Snx10Q9CWT35
Spastin (EC Kiaa1083 Spg4Q9QYY85
Speckle-type POZ protein (HIB homolog 1) (PDX-1 C-terminal-interacting factor 1)Spop Pcif1Q6ZWS85
Spermine synthase (SPMSY) (EC (Spermidine aminopropyltransferase)SmsP973555
Splicing factor 1Sf1E9Q4Q25
Sprouty-related, EVH1 domain-containing protein 1 (Spred-1)Spred1Q924S85
Sterol 26-hydroxylase, mitochondrial (EC (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) (Cytochrome P-450C27/25) (Cytochrome P450 27) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase)Cyp27a1Q9DBG15
STIP1 homology and U box-containing protein 1 (EC 6.3.2.-) (Carboxy terminus of Hsp70-interacting protein) (E3 ubiquitin-protein ligase CHIP)Stub1 ChipQ9WUD15
Stress-associated endoplasmic reticulum protein 1 (Ribosome-attached membrane protein 4)Serp1 D3Ucla1 Ramp4Q9Z1W55
Suppressor of cytokine signaling 6 (SOCS-6) (Cytokine-inducible SH2 protein 4) (CIS-4) (Suppressor of cytokine signaling 4) (SOCS-4)Socs6 Cis4 Cish4 Socs4Q9JLY05
Synaptosomal-associated protein 47 (SNAP-47) (Synaptosomal-associated 47 kDa protein)Snap47Q8R5705
Synembryn-A (Protein Ric-8A)Ric8a Ric8Q3TIR35
T-lymphocyte activation antigen CD86 (Activation B7-2 antigen) (Early T-cell costimulatory molecule 1) (ETC-1) (CD antigen CD86)Cd86P420825
Telomerase-binding protein EST1A (EC 3.1.-.-) (EST1-like protein A) (Ever shorter telomeres 1A) (Smg-6 homolog) (Telomerase subunit EST1A)Smg6 Est1a Kiaa0732P614065
THAP domain-containing protein 4Thap4Q6P3Z35
TM2 domain-containing protein 1 (Beta-amyloid-binding protein) (mBBP)Tm2d1 BbpQ99MB35
Transcription factor MafG (V-maf musculoaponeurotic fibrosarcoma oncogene homolog G)MafgO547905
Transcription factor RFX3 (Regulatory factor X 3)Rfx3P483815
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 6.3.2.-) (KRAB-A-interacting protein) (KRIP-1) (Tripartite motif-containing protein 28)Trim28 Krip1 Tif1bQ623185
Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (Silica-induced gene 41 protein) (SIG-41) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B)Tra2b Sfrs10 Silg41P629965
Translocating chain-associated membrane protein 1Tram1Q91V045
Translocation protein SEC63 homologSec63 Sec63lQ8VHE05
Transmembrane protein 41BTmem41b D7Ertd743e Kiaa0033Q8K1A55
Trinucleotide repeat-containing gene 6B proteinTnrc6b Kiaa1093Q8BKI25
tRNA selenocysteine 1-associated protein 1 (SECp43) (tRNA selenocysteine-associated protein 1)Trnau1ap Secp43 Trspap1Q80VC65
Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod)Tmod3Q9JHJ05
Tubulin alpha-4A chain (Alpha-tubulin 4) (Alpha-tubulin isotype M-alpha-4) (Tubulin alpha-4 chain)Tuba4a Tuba4P683685
Tubulin beta-2A chainTubb2a Tubb2Q7TMM95
Tubulin beta-5 chainTubb5P990245
Tyrosine-protein phosphatase non-receptor type 2 (Protein-tyrosine phosphatase PTP-2) (EC (MPTP)Ptpn2 PtptQ061805
U6 snRNA-associated Sm-like protein LSm4Lsm4Q9QXA55
Ubiquinol-cytochrome c reductase complex chaperone CBP3 homolog (Basic FGF-repressed Zic-binding protein) (mbFZb)Uqcc BfzbQ9CWU65
Ubiquitin-conjugating enzyme E2 B (EC (E214K) (RAD6 homolog B) (HR6B) (mHR6B) (Ubiquitin carrier protein B) (Ubiquitin-protein ligase B)Ube2b Rad6bP631475
Ubiquitin-conjugating enzyme E2 J2 (EC (Non-canonical ubiquitin-conjugating enzyme 2) (NCUBE-2)Ube2j2 Ncube2Q6P0735
Ubiquitin-conjugating enzyme E2 R2 (EC (Ubiquitin carrier protein R2) (Ubiquitin-conjugating enzyme E2-CDC34B) (Ubiquitin-protein ligase R2)Ube2r2 Cdc34b Ubc3bQ6ZWZ25
Ubiquitin-like-conjugating enzyme ATG3 (EC 6.3.2.-) (Autophagy-related protein 3) (APG3-like)Atg3 Apg3lQ9CPX65
UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT) (mUGT1)Slc35a2 Ugt1Q9R0M85
UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase) (UDP-glucose ceramide glucosyltransferase-like 1)Uggt1 Gt Ugcgl1 Uggt Ugt1 UgtrQ6P5E45
UMP-CMP kinase (EC (Deoxycytidylate kinase) (CK) (dCMP kinase) (Nucleoside-diphosphate kinase) (EC (Uridine monophosphate/cytidine monophosphate kinase) (UMP/CMP kinase) (UMP/CMPK)Cmpk1 Cmk Cmpk Uck Umk UmpkQ9DBP55
Uncharacterized protein C12orf4 homologD6Wsu163eQ91YN05
Uncharacterized protein C12orf43 homolog0Q3UY345
Uncharacterized protein C16orf90 homolog0Q8BT885
Uncharacterized protein C8orf47 homolog0Q8K0S25
UPF0184 protein C9orf16 homolog0P586865
UPF0461 protein C5orf24 homolog0Q80X325
UPF0471 protein C1orf63 homologD4Wsu53e MNCb-0169Q3UC655
UPF0538 protein C2orf76 homolog0Q9CRW35
Upstream stimulatory factor 2 (Major late transcription factor 2) (Upstream transcription factor 2)Usf2Q647055
V-type proton ATPase subunit C 1 (V-ATPase subunit C 1) (Vacuolar proton pump subunit C 1)Atp6v1c1 Atp6c Atp6c1 VatcQ9Z1G35
Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R)VldlrP981565
Very-long-chain enoyl-CoA reductase (EC (Synaptic glycoprotein SC2) (Trans-2,3-enoyl-CoA reductase) (TER)Tecr Gpsn2Q9CY275
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1-like protein 1)Vkorc1l1Q6TEK55
WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2)Wipi2Q80W475
WD repeat-containing protein mioMiosQ8VE195
WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed]Smu1Q3UKJ75
WW domain binding protein 1-like (Outcome predictor in acute leukemia 1 homolog)Wbp1l D19Wsu162e Opal1Q8BGW25
Zinc finger and BTB domain-containing protein 20 (BTB/POZ domain zinc finger factor HOF) (Zinc finger protein 288)Zbtb20 Zfp288Q8K0L95
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