EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Phosphoinositide phospholipase C (EC 3.1.4.11)Plcg1 mCG_15356A2A4A62
Phospholipase A1 member A (EC 3.1.1.-) (Phosphatidylserine-specific phospholipase A1) (PS-PLA1)Pla1a Pspla1Q8VI782
Phospholipase C, beta 4 (Fragment)Plcb4A2AT932
Phosphomevalonate kinase (PMKase) (EC 2.7.4.2)PmvkD3YXP62
Phosphoprotein-enriched in astrocytes 15A (Fragment)Pea15aD3Z3752
Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta)PhkbQ7TSH22
Phytanoyl-CoA hydroxylase-interacting protein-likePhyhiplQ8BGT82
Placenta-specific protein 9Plac9Q8K2622
Plakophilin 2Pkp2E0CX592
Plakophilin-1Pkp1P973502
Plastin-3 (Fragment)Pls3A0A1C7CYV02
Platelet endothelial aggregation receptor 1 (mPEAR1) (Jagged and Delta protein) (Protein Jedi) (Multiple epidermal growth factor-like domains protein 12) (Multiple EGF-like domains protein 12)Pear1 Jedi Megf12Q8VIK52
Platelet glycoprotein Ib alpha chain (GP-Ib alpha) (GPIb-alpha) (GPIbA) (Glycoprotein Ibalpha) (CD antigen CD42b)Gp1baO359302
Platelet glycoprotein V (Fragment)Gp5Q9QZU32
Platelet-activating factor acetylhydrolase 2, cytoplasmic (EC 3.1.1.47) (Serine-dependent phospholipase A2) (SD-PLA2)Pafah2Q8VDG72
Platelet-derived growth factor C (PDGF-C) (Fallotein) (Spinal cord-derived growth factor) (SCDGF) (VEGF-E) [Cleaved into: Platelet-derived growth factor C, latent form (PDGFC latent form); Platelet-derived growth factor C, receptor-binding form (PDGFC receptor-binding form)]Pdgfc ScdgfQ8CI192
Pleckstrin homology domain-containing family F member 2 (Fragment)Plekhf2A8Y5N82
PlectinPlecE9Q3W42
Plexin domain-containing protein 2 (Tumor endothelial marker 7-related protein)Plxdc2 Tem7rQ9DC112
Plexin-A3Plxna3P702082
Plexin-C1 (Virus-encoded semaphorin protein receptor) (CD antigen CD232)Plxnc1 VesprQ9QZC22
PodocanPodnQ7TQ622
Poly [ADP-ribose] polymerase (PARP) (EC 2.4.2.30)Parp1Q3TF182
Polyadenylate-binding protein (PABP)Gm10110D3Z5M22
Polyadenylate-binding protein (PABP)Pabpc1l EpabA2A5N32
Polyadenylate-binding protein 1 (Fragment)Pabpc1F6ZAX12
Polyadenylate-binding protein 2 (Fragment)Pabpn1D3YUB92
Polyadenylate-binding protein-interacting protein 1Paip1G3UYE52
Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1) (PAIP-1) (Poly(A)-binding protein-interacting protein 1)Paip1Q8VE622
Polycomb group RING finger protein 6 (Mel18 and Bmi1-like RING finger) (RING finger protein 134)Pcgf6 Mblr Rnf134Q99NA92
Polymerase delta-interacting protein 3 (S6K1 Aly/REF-like target) (SKAR)Poldip3Q8BG812
Polypeptide N-acetylgalactosaminyltransferase (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase) (Fragment)Galnt2Q3UM522
Polypeptide N-acetylgalactosaminyltransferase 6 (EC 2.4.1.41) (Polypeptide GalNAc transferase 6) (GalNAc-T6) (pp-GaNTase 6) (Protein-UDP acetylgalactosaminyltransferase 6) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 6)Galnt6Q8C7U72
Polypyrimidine tract-binding protein 2 (Brain-enriched polypyrimidine tract-binding protein) (Brain-enriched PTB) (Neural polypyrimidine tract-binding protein) (RRM-type RNA-binding protein brPTB)Ptbp2 Brptb NptbQ91Z312
Potassium-transporting ATPase alpha chain 1 (EC 3.6.3.10) (Gastric H(+)/K(+) ATPase subunit alpha) (Proton pump)Atp4aQ644362
Pre-mRNA-splicing regulator WTAP (Female-lethal(2)D homolog) (WT1-associated protein) (Wilms tumor 1-associating protein)WtapQ9ER692
Prefoldin subunit 3 (Putative uncharacterized protein)Vbp1Q3TIR62
Presenilin-2 (PS-2) (EC 3.4.23.-) [Cleaved into: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit]Psen2 Ad4h Alg3 Ps-2 Psnl2Q611442
PRKC apoptosis WT1 regulator protein (Prostate apoptosis response 4 protein) (Par-4)Pawr Par4Q925B02
Probable 18S rRNA (guanine-N(7))-methyltransferase (EC 2.1.1.-) (Bud site selection protein 23 homolog) (Williams-Beuren syndrome chromosomal region 22 protein homolog) (rRNA methyltransferase and ribosome maturation factor)Bud23 Wbscr22Q9CY212
Probable aminopeptidase NPEPL1 (EC 3.4.11.-) (Aminopeptidase-like 1)Npepl1Q6NSR82
Probable ATP-dependent RNA helicase DDX10 (EC 3.6.4.13) (DEAD box protein 10)Ddx10Q80Y442
Probable ATP-dependent RNA helicase DHX40 (EC 3.6.4.13) (DEAH box protein 40)Dhx40Q6PE542
Probable E3 ubiquitin-protein ligase RNF217 (EC 2.3.2.-) (IBR domain-containing protein 1) (RING finger protein 217)Rnf217 Ibrdc1D3YYI72
Probable ergosterol biosynthetic protein 28ORF11Q9ERY92
Probable helicase with zinc finger domain (EC 3.6.4.-)Helz Kiaa0054Q6DFV52
Probable histidine--tRNA ligase, mitochondrial (EC 6.1.1.21) (Histidine--tRNA ligase-like) (Histidyl-tRNA synthetase) (HisRS)Hars2 HarslQ99KK92
Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 8) (DHHC-8)Zdhhc8Q5Y5T52
Probable threonine protease PRSS50 (EC 3.4.25.-) (Serine protease 50) (Testis-specific protease-like protein 50)Prss50 Tsp50Q8BLH52
Probable tRNA(His) guanylyltransferase (EC 2.7.7.79) (tRNA-histidine guanylyltransferase)Thg1lQ9CY522
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (Fragment)Usp9xG3UY522
Processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae) (Putative uncharacterized protein)Pop1Q9D4G52
Proepiregulin [Cleaved into: Epiregulin (EPR)]EregQ615212
Prolyl 3-hydroxylase 3 (EC 1.14.11.7) (Leprecan-like protein 2) (Protein B)P3h3 Leprel2Q8CG702
Prolyl 3-hydroxylase OGFOD1 (EC 1.14.11.-) (2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1)Ogfod1 Kiaa1612Q3U0K82
Prolyl endopeptidase FAP (EC 3.4.21.26) (Dipeptidyl peptidase FAP) (EC 3.4.14.5) (Fibroblast activation protein alpha) (FAPalpha) (Gelatine degradation protease FAP) (EC 3.4.21.-) (Integral membrane serine protease) (Post-proline cleaving enzyme) (Serine integral membrane protease) (SIMP) (Surface-expressed protease) (Seprase) [Cleaved into: Antiplasmin-cleaving enzyme FAP, soluble form (APCE) (EC 3.4.14.5) (EC 3.4.21.-) (EC 3.4.21.26)]FapP973212
Proprotein convertase subtilisin/kexin type 6Pcsk6F6XJP72
Prostacyclin synthase (EC 5.3.99.4) (Prostaglandin I2 synthase)Ptgis Cyp8O350742
Prostaglandin reductase-3 (PTGR-3) (EC 1.3.1.48) (15-oxoprostaglandin 13-reductase) (Zinc-binding alcohol dehydrogenase domain-containing protein 2)Zadh2 Ptgr3Q8BGC42
Prostaglandin-H2 D-isomerase (EC 5.3.99.2) (Glutathione-independent PGD synthase) (Lipocalin-type prostaglandin-D synthase) (Prostaglandin-D2 synthase) (L-PGDS) (PGD2 synthase) (PGDS2)PtgdsO091142
Prostate stem cell antigenPscaP570962
Prostatic acid phosphatase (EC 3.1.3.2) (5'-nucleotidase) (5'-NT) (EC 3.1.3.5) (Ecto-5'-nucleotidase) (Fluoride-resistant acid phosphatase) (FRAP) (Thiamine monophosphatase) (TMPase)AcppQ8CE082
Protease, serine, 3Prss3 Gm10334B9EJ352
Proteasome activator complex subunit 1Psme1G3X9K92
Proteasome activator complex subunit 3 (Fragment)Psme3A2A4J32
Proteasome subunit alpha type (EC 3.4.25.1)Psma2Q3UWT62
Protein AATF (Apoptosis-antagonizing transcription factor) (Rb-binding protein Che-1) (Traube protein)Aatf Che1 TrbQ9JKX42
Protein bicaudal D homolog 2 (Bic-D 2)Bicd2 Kiaa0699Q921C52
Protein BUD31 homologBud31E0CX202
Protein BUD31 homolog (Protein G10 homolog)Bud31Q6PGH12
Protein chibby homolog 1 (Cytosolic leucine-rich protein) (PIGEA-14) (PKD2 interactor, Golgi and endoplasmic reticulum-associated 1)Cby1 Cby Pgea1Q9D1C22
Protein diaphanous homolog 1Diaph1E9PV412
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 72)Pdia4A0A0R4J0Z12
Protein disulfide-isomerase A5 (EC 5.3.4.1) (Protein disulfide isomerase-related protein)Pdia5 PdirQ921X92
Protein Dr1 (Down-regulator of transcription 1) (Negative cofactor 2-beta) (NC2-beta) (TATA-binding protein-associated phosphoprotein)Dr1Q91WV02
Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)Ect2 mKIAA4037Q071392
Protein enabled homologEnahE9QLZ92
Protein eva-1 homolog A (Fragment)Eva1a Fam176aD3Z5112
Protein EVI2A (Ecotropic viral integration site 2A protein) (EVI-2A)Evi2a Evi-2 Evi-2a Evi2P209342
Protein EVI2B (Ecotropic viral integration site 2B protein) (EVI-2B) (CD antigen CD361)Evi2bQ8VD582
Protein FAM114A2Fam114a2Q8VE882
Protein FAM168AFam168a Kiaa0280Q8BGZ22
Protein fem-1 homolog C (FEM1c) (FEM1-gamma)Fem1c Kiaa1785Q8CEF12
Protein HEG homolog 1Heg1E9Q4402
Protein IMPACT (Imprinted and ancient gene protein)ImpactO550912
Protein Jumonji (Jumonji/ARID domain-containing protein 2)Jarid2 JmjQ623152
Protein kinase C (EC 2.7.11.13)Prkca mCG_140727Q4VA932
Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)Prkcb Pkcb Prkcb1P684042
Protein kishTmem167 mCG_116561E0CY072
Protein LLP homolog (Protein LAPS18-like)LlphQ9D9452
Protein LSM14 homolog A (Protein FAM61A) (RNA-associated protein 55A) (mRAP55A)Lsm14a Fam61a Rap55aQ8K2F82
Protein LSM14 homolog B (Protein FAM61B) (RNA-associated protein 55B) (mRAP55B)Lsm14b Fam61b Rap55bQ8CGC42
Protein LTV1 homologLtv1Q6NSQ72
Protein mago nashi homolog 2MagohbG3UZW72
Protein MAL2Mal2Q8BI082
Protein myomaker (Transmembrane protein 8C)Tmem8cQ9D1N42
Protein NDRG2 (N-myc downstream-regulated gene 2 protein) (Protein Ndr2)Ndrg2 Kiaa1248 Ndr2Q9QYG02
Protein NEDD1 (Neural precursor cell expressed developmentally down-regulated protein 1) (NEDD-1)Nedd1 Nedd-1P332152
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-)Pomgnt1Q91X882
Protein phosphatase 1 regulatory inhibitor subunit 16B (CAAX box protein TIMAP) (TGF-beta-inhibited membrane-associated protein)Ppp1r16bQ8VHQ32
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